| Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane J Yin, KYM Chen, MJ Clark, M Hijazi, P Kumari, X Bai, RK Sunahara, ... Nature 584 (7819), 125-129, 2020 | 192 | 2020 |
| Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma C Santiskulvong, GE Konecny, M Fekete, KYM Chen, A Karam, ... Clinical Cancer Research 17 (8), 2373-2384, 2011 | 131 | 2011 |
| Computational design of G Protein-Coupled Receptor allosteric signal transductions KYM Chen, D Keri, P Barth Nature Chemical Biology 16 (1), 77-86, 2020 | 65 | 2020 |
| Naturally evolved G protein-coupled receptors adopt metastable conformations KYM Chen, F Zhou, BG Fryszczyn, P Barth Proceedings of the National Academy of Sciences 109 (33), 13284-13289, 2012 | 53 | 2012 |
| Reciprocal H3. 3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling KY Chen, K Bush, RH Klein, V Cervantes, N Lewis, A Naqvi, ... Communications biology 3 (1), 363, 2020 | 46 | 2020 |
| Computational design of ligand-binding membrane receptors with high selectivity X Feng, J Ambia, KYM Chen, M Young, P Barth Nature chemical biology 13 (7), 715-723, 2017 | 42 | 2017 |
| High-resolution modeling of transmembrane helical protein structures from distant homologues KYM Chen, J Sun, JS Salvo, D Baker, P Barth PLoS computational biology 10 (5), e1003636, 2014 | 40 | 2014 |
| Induction of neurite outgrowth from chick embryonic ganglia explants by activators of protein kinase C L Hsu, AY Jeng, KY Chen Neuroscience letters 99 (3), 257-262, 1989 | 35 | 1989 |
| To CRISPR and beyond: the evolution of genome editing in stem cells KY Chen, PS Knoepfler Regenerative medicine 11 (8), 801-816, 2016 | 22 | 2016 |
| Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways M Young, T Dahoun, B Sokrat, C Arber, KM Chen, M Bouvier, P Barth Proceedings of the National Academy of Sciences 115 (27), 7051-7056, 2018 | 14 | 2018 |
| Nicotinannide and PI3K inhibitors suppression of senescent cell phenotypes involving autophagy signaling. K Matuoka, K Sasaki, KY Chen MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
| Requirement for the functions of NF-Y transcription factor A, B and C subunits and p38 MAP kinase in neurite outgrowth in PC12 cells. K Matuoka, K Sasaki, S Imaizumi, KY Chen MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
| Nicotinamide reverses senescent cell phenotype: possible differential role of phosphatidylinositol 3-kinase subtype enzymes. K Matuoka, K Sasaki, K Nakanishi, T Ilda, KY Chen MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |
| Modeling Membrane Protein Structures from Distant Homologues with Near-Atomic Accuracy: 712 K Chen, J Sun, S Salvo, D Baker, P Barth Protein Science 22, 2013 | | 2013 |
| Reprogramming the Conformational Regulation of G Protein-Coupled Receptor Signaling: 429 KY Chen, P Barth Protein Science 22, 2013 | | 2013 |
| Involvement of phosphatidylinositol 3-kinase signaling in nicotinamide suppression of senescent cell phenotypes K Matuoka, K Sasaki, K Nakanishi, KY Chen MOLECULAR BIOLOGY OF THE CELL 24, 2013 | | 2013 |
| Suppression of neurite elongation in PC12 cells due to NF-YA and NF-YC knockdown. K Matuoka, K Sasaki, KY Chen MOLECULAR BIOLOGY OF THE CELL 23, 2012 | | 2012 |
