Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection S Seal, J Carreras-Puigvert, MA Trapotsi, H Yang, O Spjuth, A Bender Communications Biology 5 (1), 858, 2022 | 47* | 2022 |
Comparison of cellular morphological descriptors and molecular fingerprints for the prediction of cytotoxicity-and proliferation-related assays S Seal, H Yang, L Vollmers, A Bender Chemical Research in Toxicology 34 (2), 422-437, 2021 | 35 | 2021 |
Using chemical and biological data to predict drug toxicity A Liu, S Seal, H Yang, A Bender SLAS Discovery 28 (3), 53-64, 2023 | 24 | 2023 |
Merging bioactivity predictions from cell morphology and chemical fingerprint models using similarity to training data S Seal, H Yang, MA Trapotsi, S Singh, J Carreras-Puigvert, O Spjuth, ... Journal of Cheminformatics 15 (1), 56, 2023 | 21 | 2023 |
From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretability S Seal, J Carreras-Puigvert, S Singh, AE Carpenter, O Spjuth, A Bender Molecular Biology of the Cell 35 (3), mr2, 2024 | 8 | 2024 |
Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank S Seal, O Spjuth, L Hosseini-Gerami, M García-Ortegón, S Singh, ... Journal of Chemical Information and Modeling 64 (4), 1172-1186, 2024 | 7 | 2024 |
Using generative modeling to endow with potency initially inert compounds with good bioavailability and low toxicity RI Horne, J Wilson-Godber, A González Díaz, ZF Brotzakis, S Seal, ... Journal of Chemical Information and Modeling 64 (3), 590-596, 2024 | 6 | 2024 |
Improved Detection of Drug-Induced Liver Injury by Integrating Predicted In Vivo and In Vitro Data S Seal, D Williams, L Hosseini-Gerami, M Mahale, AE Carpenter, ... Chemical Research in Toxicology, 2024 | 3 | 2024 |
PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules S Seal, M Trapotsi, V Subramanian, O Spjuth, N Greene, A Bender bioRxiv, 2024.02. 02.578658, 2024 | 2 | 2024 |
A Decade in a Systematic Review: The Evolution and Impact of Cell Painting S Seal, MA Trapotsi, O Spjuth, S Singh, J Carreras-Puigvert, N Greene, ... ArXiv, 2024 | 1 | 2024 |
Understanding Biology in the Age of Artificial Intelligence E Lawrence, A El-Shazly, S Seal, CK Joshi, P Liò, S Singh, A Bender, ... arXiv preprint arXiv:2403.04106, 2024 | 1 | 2024 |
Calibrated prediction of scarce adverse drug reaction labels with conditional neural processes M Garcia Ortegon, S Seal, S Singh, A Bender, S Bacallado ICLR 2024 DMLR Workshop, 2024 | 1 | 2024 |
Learning Molecular Representation in a Cell G Liu, S Seal, J Arevalo, Z Liang, AE Carpenter, M Jiang, S Singh arXiv preprint arXiv:2406.12056, 2024 | | 2024 |
Step Forward Cross Validation for Bioactivity Prediction: Out of Distribution Validation in Drug Discovery US Saha, M Vendruscolo, AE Carpenter, S Singh, A Bender, S Seal bioRxiv, 2024.07. 02.601740, 2024 | | 2024 |
Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection S Seal, J Carreras-Puigvert, MA Trapotsi, H Yang, O Spjuth, A Bender Communications Biology 5 (1), 858, 2022 | | 2022 |