Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ... Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019 | 129 | 2019 |
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ... Cell host & microbe 16 (1), 128-140, 2014 | 127 | 2014 |
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3 RJ Wall, E Rico, I Lukac, F Zuccotto, S Elg, IH Gilbert, Y Freund, ... Proceedings of the National Academy of Sciences 115 (38), 9616-9621, 2018 | 113 | 2018 |
Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes M Roques, RJ Wall*, AP Douglass, A Ramaprasad, DJP Ferguson, ... PLoS pathogens 11 (11), e1005273 *Joint first author, 2015 | 66 | 2015 |
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite B Poulin, EM Patzewitz, D Brady, O Silvie, MH Wright, DJP Ferguson, ... Biology open 2 (11), 1160-1170, 2013 | 65 | 2013 |
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani V Corpas-Lopez, S Moniz, M Thomas, RJ Wall, LS Torrie, D Zander-Dinse, ... ACS infectious diseases 5 (1), 111-122, 2018 | 63 | 2018 |
An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission EM Patzewitz, DS Guttery, B Poulin, C Ramakrishnan, DJP Ferguson, ... Cell reports 3 (3), 622-629, 2013 | 57 | 2013 |
The Repeat Region of the Circumsporozoite Protein is Critical for Sporozoite Formation and Maturation in Plasmodium DJP Ferguson, AE Balaban, EM Patzewitz, RJ Wall, CS Hopp, B Poulin, ... PloS one 9 (12), e113923, 2014 | 56 | 2014 |
Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility JL Green, RJ Wall, J Vahokoski, NA Yusuf, MAM Ridzuan, RR Stanway, ... Journal of Biological Chemistry 292 (43), 17857-17875, 2017 | 42 | 2017 |
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis CE Mowbray, S Braillard, PA Glossop, GA Whitlock, RT Jacobs, J Speake, ... Journal of Medicinal Chemistry 64 (21), 16159–16176, 2021 | 41 | 2021 |
SAS6-like protein in Plasmodium indicates that conoid-associated apical complex proteins persist in invasive stages within the mosquito vector RJ Wall, M Roques, NJ Katris, L Koreny, RR Stanway, D Brady, RF Waller, ... Scientific reports 6 (1), 28604, 2016 | 40 | 2016 |
Characterisation of chlorinated, brominated and mixed halogenated dioxins, furans and biphenyls as potent and as partial agonists of the Aryl hydrocarbon receptor RJ Wall, A Fernandes, M Rose, DR Bell, IR Mellor Environment international 76, 49-56, 2015 | 40 | 2015 |
The Plasmodium class XIV myosin, MyoB, has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain NA Yusuf, JL Green, RJ Wall, E Knuepfer, RW Moon, C Schulte-Huxel, ... Journal of Biological Chemistry 290 (19), 12147-12164, 2015 | 38 | 2015 |
Systematic analysis of Plasmodium myosins reveals differential expression, localization and function in invasive and proliferative parasite stages RJ Wall, M Zeeshan, NJ Katris, R Limenitakis, E Rea, J Stock, D Brady, ... Cellular microbiology 21 (10), e13082, 2019 | 36 | 2019 |
Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis RJ Wall, DJP Ferguson, A Freville, B Franke-Fayard, D Brady, M Zeeshan, ... Scientific Reports 8 (1), 5610, 2018 | 36 | 2018 |
The role of folate transport in antifolate drug action in Trypanosoma brucei S Dewar, N Sienkiewicz, HB Ong, RJ Wall, D Horn, AH Fairlamb Journal of Biological Chemistry 291 (47), 24768-24778, 2016 | 27 | 2016 |
Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission R Pandey, S Abel, M Boucher, RJ Wall, M Zeeshan, E Rea, A Freville, ... Cell reports 30, 1-15, 2020 | 26 | 2020 |
The Qi site of cytochrome b is a promiscuous drug target in Trypanosoma cruzi and Leishmania donovani RJ Wall, S Carvalho, R Milne, JA Bueren-Calabuig, S Moniz, ... ACS infectious diseases 6 (3), 515-528, 2020 | 25 | 2020 |
Mixed halogenated dioxins/furans (PXDD/Fs) and biphenyls (PXBs) in food: occurrence and toxic equivalent exposure using specific relative potencies AR Fernandes, D Mortimer, RJ Wall, DR Bell, M Rose, M Carr, S Panton, ... Environment international 73, 104-110, 2014 | 24 | 2014 |
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context RJ Wall, G He, MS Denison, C Congiu, V Onnis, A Fernandes, DR Bell, ... Toxicology 297 (1-3), 26-33, 2012 | 20 | 2012 |