A biomimetic approach for enhancing the in vivo half-life of peptides SC Penchala, MR Miller, A Pal, J Dong, NR Madadi, J Xie, H Joo, J Tsai, ... Nature chemical biology 11 (10), 793-798, 2015 | 129 | 2015 |
Enthalpy-driven stabilization of transthyretin by AG10 mimics a naturally occurring genetic variant that protects from transthyretin amyloidosis M Miller, A Pal, W Albusairi, H Joo, B Pappas, MT Haque Tuhin, D Liang, ... Journal of medicinal chemistry 61 (17), 7862-7876, 2018 | 69 | 2018 |
Phytochemical Screening and In vitro Evaluation of Pharmacological Activities of Aphanamixis polystachya (Wall) Parker Fruit Extracts AS Apu, FA Chowdhury, F Khatun, ATM Jamaluddin, AH Pathan, A Pal Tropical Journal of Pharmaceutical Research 12 (1), 111-116, 2013 | 50 | 2013 |
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug R Rais, KM Lemberg, L Tenora, ML Arwood, A Pal, J Alt, Y Wu, J Lam, ... Science advances 8 (46), eabq5925, 2022 | 47 | 2022 |
A comparative study of the antioxidant, antimicrobial and thrombolytic activity of the bark and leaves of Lannea coromandelica (Anacardiaceae) MK Manik, MA Wahid, SMA Islam, A Pal, KT Ahmed International Journal of Pharmaceutical Sciences and Research 4 (7), 2609, 2013 | 41 | 2013 |
Nipping disease in the bud: nSMase2 inhibitors as therapeutics in extracellular vesicle-mediated diseases C Tallon, KR Hollinger, A Pal, BJ Bell, R Rais, T Tsukamoto, KW Witwer, ... Drug discovery today 26 (7), 1656-1668, 2021 | 25 | 2021 |
Hydrophilic small molecules that harness transthyretin to enhance the safety and efficacy of targeted chemotherapeutic agents A Pal, W Albusairi, F Liu, MTH Tuhin, M Miller, D Liang, H Joo, TU Amin, ... Molecular Pharmaceutics 16 (7), 3237-3252, 2019 | 21 | 2019 |
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury C Tallon, S Picciolini, SW Yoo, AG Thomas, A Pal, J Alt, C Carlomagno, ... Biochemical pharmacology 194, 114796, 2021 | 17 | 2021 |
Evaluation of antinociceptive, antidiarrheal and antimicrobial activities of leaf extracts of Clerodendrum indicum A Pal, Z Al Mahmud, N Akter, S Islam, SC Bachar Pharmacognosy Journal 4 (30), 41-46, 2012 | 16 | 2012 |
Dendrimer-conjugated nSMase2 inhibitor reduces tau propagation in mice C Tallon, BJ Bell, A Sharma, A Pal, MM Malvankar, AG Thomas, SW Yoo, ... Pharmaceutics 14 (10), 2066, 2022 | 9 | 2022 |
Analysis of cytotypes of Dioscorea and scope of increasing the diosgenin content [tropical and subtropical genus; yam; sapogenin; diosgenin drug; contraceptives]. A Pal, AK Sharma Cellule 73, 1980 | 9 | 1980 |
Discovery of orally bioavailable and brain-penetrable prodrugs of the potent nSmase2 inhibitor DPTIP A Pal, S Gori, S Yoo, AG Thomas, Y Wu, J Friedman, L Tenora, H Bhasin, ... Journal of medicinal chemistry 65 (16), 11111-11125, 2022 | 8 | 2022 |
Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand TU Amin, R Emara, A Pal, H Aldawod, G Jiang, D Liang, MT Haque Tuhin, ... Journal of Medicinal Chemistry 65 (22), 15473-15486, 2022 | 5 | 2022 |
Glutamine antagonist GA-607 causes a dramatic accumulation of FGAR which can be used to monitor target engagement J Alt, SS Gori, KM Lemberg, A Pal, V Veeravalli, Y Wu, JMH Aguilar, ... Current drug metabolism 22 (9), 735, 2021 | 5 | 2021 |
D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II SS Gori, AG Thomas, A Pal, R Wiseman, DV Ferraris, R Gao, Y Wu, J Alt, ... Pharmaceutics 14 (10), 2018, 2022 | 3 | 2022 |
Cytological and developmental aspects of callus in Costus speciosus A Pal, AK Sharma Tissue culture of economically important plants: proceedings of the …, 1982 | 3 | 1982 |
Diosgenin content of Old and New World species of Dioscorea with special reference to the chromosomal races. A Pal, AK Sharma | 3 | 1977 |
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ... Translational Neurodegeneration 12 (1), 56, 2023 | 2 | 2023 |
Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor RD Gao, N Hin, E Prchalová, A Pal, J Lam, R Rais, BS Slusher, ... Bioorganic & medicinal chemistry letters 50, 128321, 2021 | 2 | 2021 |
Chromosomal stability in callus cultures of Chrysanthemum cinerariaefolium as determinant of embryogenesis. A Pal | 2 | 1992 |