Modulation of brain ACE and ACE2 may be a promising protective strategy against cerebral ischemia/reperfusion injury: an experimental trial in rats MM Abdel-Fattah, BAS Messiha, AM Mansour Naunyn-Schmiedeberg's archives of pharmacology 391, 1003-1020, 2018 | 36 | 2018 |
The potential effect of the angiotensin II receptor blocker telmisartan in regulating OVA-induced airway remodeling in experimental rats MM Abdel-Fattah, AAA Salama, BA Shehata, IE Ismaiel Pharmacological Reports 67, 943-951, 2015 | 33 | 2015 |
Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks AH Abdelazeem, AGS El-Din, MM Abdel-Fattah, NH Amin, ... European Journal of Medicinal Chemistry 205, 112662, 2020 | 28 | 2020 |
Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: impact on oxidative stress and ACE2/Ang-(1–7) signaling MM Abdel-Fattah, ANAM Elgendy, WR Mohamed Life Sciences 275, 119387, 2021 | 24 | 2021 |
Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory … AM Sayed, MM Abdel-Fattah, HH Arab, WR Mohamed, EHM Hassanein Chemico-biological interactions 351, 109732, 2022 | 23 | 2022 |
New indomethacin analogs as selective COX‐2 inhibitors: Synthesis, COX‐1/2 inhibitory activity, anti‐inflammatory, ulcerogenicity, histopathological, and docking studies KRA Abdellatif, EKA Abdelall, HAH Elshemy, ES El‐Nahass, ... Archiv der Pharmazie 354 (4), 2000328, 2021 | 17 | 2021 |
Assessment of the mechanistic role of cinnarizine in modulating experimentally-induced bronchial asthma in rats MM Abdel-Fattah, BAS Messiha, AAA Salama Pharmacology 96 (3-4), 167-174, 2015 | 17 | 2015 |
Design and synthesis of new indole drug candidates to treat Alzheimer’s disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy PF Lamie, MM Abdel-Fattah, JN Philoppes Journal of enzyme inhibition and medicinal chemistry 37 (1), 2660-2678, 2022 | 12 | 2022 |
Role of NF-κB/ICAM-1, JAK/STAT-3, and apoptosis signaling in the anticancer effect of tangeretin against urethane-induced lung cancer in BALB/c mice MM Abdel-Fattah, WR Mohamed, EHM Hassanein, HA Arab, ... Life Sciences 325, 121749, 2023 | 8 | 2023 |
Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT pathways with rebamipide attenuates acetic acid-induced colitis in rats MM Abdel-Fattah, EHM Hassanein, AM Sayed, SE Alsufyani, ... Pharmaceuticals 16 (4), 533, 2023 | 8 | 2023 |
Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia ME Abo-El Fetoh, MM Abdel-Fattah, WR Mohamed, LAA Ramadan, ... Inflammopharmacology 31 (1), 499-516, 2023 | 7 | 2023 |
Discovery and optimization of 2, 3-diaryl-1, 3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity AM Shawky, FA Almalki, AN Abdalla, BGM Youssif, MM Abdel-Fattah, ... European Journal of Medicinal Chemistry 259, 115712, 2023 | 3 | 2023 |
Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological … NH Amin, MT El-Saadi, MM Abdel-Fattah, AA Mohammed, EG Said Bioorganic Chemistry 135, 106496, 2023 | 3 | 2023 |
Novel pyrazole-oxadiazole hybrids possessing methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory … KRA Abdellatif, EKA Abdelall, PF Lamie, MB Labib, MM Abdelhakeem, ... Journal of Molecular Structure 1266, 133529, 2022 | 3 | 2022 |
Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects NH Amin, MIA Hamed, MM Abdel-Fattah, AHA Abusabaa, MT El-Saadi Bioorganic Chemistry 116, 105394, 2021 | 2 | 2021 |
Review on EGFR-ERK1/2 signaling cascade: implications on cell proliferation in health and disease ME Abo-El Fetoh, MM Abdel-Fattah, H Afify, LAA Ramadan, ... Egyptian Pharmaceutical Journal, 2023 | 1 | 2023 |
Probenecid ameliorates testosterone‐induced benign prostatic hyperplasia: Implications of PGE‐2 on ADAM‐17/EGFR/ERK1/2 signaling cascade MM Abdel‐Fattah, ME Abo‐El Fetoh, H Afify, LAA Ramadan, ... Journal of Biochemical and Molecular Toxicology 37 (11), e23450, 2023 | 1 | 2023 |
Immunomodulatory and anti-inflammatory effects of N-acetylcysteine in ovalbumin-sensitized rats MM Abdel-Fattah, AAA Salama, BAS Messiha Beni-Suef University Journal of Basic and Applied Sciences 11, 1-9, 2022 | 1 | 2022 |
Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides EKA Abdelall, HAH Elshemy, JN Philoppes, MM Abdel-Fattah, ... Bioorganic Chemistry 143, 107098, 2024 | | 2024 |
The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats MM Abdel‐Fattah, AM Ahmed, RK Saleh, BAS Messiha, RR Rofaeil Fundamental & Clinical Pharmacology, e13027, 2024 | | 2024 |