Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13452* | 2016 |
ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion N Tobar, V Villar, JF Santibanez Molecular and cellular biochemistry 340, 195-202, 2010 | 194 | 2010 |
Glutaminolysis and autophagy in cancer VH Villar, F Merhi, M Djavaheri-Mergny, RV Durán Autophagy 11 (8), 1198-1208, 2015 | 129 | 2015 |
mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation VH Villar, TL Nguyen, V Delcroix, S Terés, M Bouchecareilh, B Salin, ... Nature communications 8 (1), 14124, 2017 | 78 | 2017 |
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication H Hulme, LM Meikle, N Strittmatter, JJJ van der Hooft, J Swales, RA Bragg, ... Science Advances 6 (11), eaax6328, 2020 | 57 | 2020 |
Nilotinib counteracts P-glycoprotein-mediated multidrug resistance and synergizes the antitumoral effect of doxorubicin in soft tissue sarcomas VH Villar, O Vögler, J Martínez-Serra, R Ramos, S Calabuig-Farinas, ... PloS one 7 (5), e37735, 2012 | 44 | 2012 |
Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis C Bodineau, M Tomé, S Courtois, ASH Costa, M Sciacovelli, B Rousseau, ... Nature Communications 12 (1), 4814, 2021 | 35 | 2021 |
Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein VH Villar, O Vögler, F Barceló, M Gómez-Florit, J Martínez-Serra, ... The Journal of nutritional biochemistry 25 (4), 429-438, 2014 | 34 | 2014 |
Nilotinib as coadjuvant treatment with doxorubicin in patients with sarcomas: a phase I trial of the spanish group for research on sarcoma R Alemany, DS Moura, A Redondo, J Martinez-Trufero, S Calabuig, ... Clinical Cancer Research 24 (21), 5239-5249, 2018 | 26 | 2018 |
The Metabolic Features of Tumor‐Associated Macrophages: Opportunities for Immunotherapy? SS Mojsilovic, S Mojsilovic, VH Villar, JF Santibanez Analytical Cellular Pathology 2021 (1), 5523055, 2021 | 18 | 2021 |
SKIP is required for TGF-β1-induced epithelial mesenchymal transition and migration in transformed keratinocytes V Villar, J Kocic, D Bugarski, G Jovcic, JF Santibanez FEBS letters 584 (22), 4586-4592, 2010 | 17 | 2010 |
Spred2 inhibits TGF‐β1‐induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition V Villar, J Kocić, JF Santibanez International journal of cancer 127 (1), 77-85, 2010 | 16 | 2010 |
Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma VH Villar, O Vögler, F Barceló, J Martín-Broto, J Martínez-Serra, ... Plosone 11 (5), e0155946, 2016 | 14 | 2016 |
Glutamoptosis: A new cell death mechanism inhibited by autophagy during nutritional imbalance VH Villar, RV Durán Autophagy 13 (6), 1078-1079, 2017 | 13 | 2017 |
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer VH Villar, MF Allega, R Deshmukh, T Ackermann, MA Nakasone, ... Nature Chemical Biology 19 (3), 292-300, 2023 | 11 | 2023 |
Skip Regulates TGF‐β1‐Induced Extracellular Matrix Degrading Proteases Expression in Human PC‐3 Prostate Cancer Cells V Villar, J Kocic, JF Santibanez Prostate Cancer 2013 (1), 398253, 2013 | 11 | 2013 |
Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR VH Villar, TL Nguyen, S Terés, C Bodineau, RV Durán Molecular & Cellular Oncology 4 (3), e1297284, 2017 | 10 | 2017 |
Transforming growth factor-β1 in cancer immunology: opportunities for immunotherapy VH Villar, T Subotički, D Đikić, O Mitrović-Ajtić, F Simon, JF Santibanez Advances in Molecular Pathology, 309-328, 2023 | 7 | 2023 |
Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis G Taurino, R Deshmukh, VH Villar, M Chiu, R Shaw, A Hedley, E Shokry, ... Molecular Metabolism 63, 101532, 2022 | 4 | 2022 |
Down-regulation of the AKT/GSK3β/β-catenin signalling pathway by the triterpene ursolic acid induced intrinsic apoptosis in human soft tissue sarcomas R Alemany, VH Villar, O Vögler, JM Serra, J Martín, V Ruiz-Gutiérrez, ... Chemistry and Physics of Lipids, S27, 2010 | 3 | 2010 |