Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide W Wick, P Roth, C Hartmann, P Hau, M Nakamura, F Stockhammer, ... Neuro-oncology 18 (11), 1529-1537, 2016 | 220 | 2016 |
A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment A Griveau, G Seano, SJ Shelton, R Kupp, A Jahangiri, K Obernier, ... Cancer cell 33 (5), 874-889. e7, 2018 | 216 | 2018 |
ZFTA–RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... Cancer discovery 11 (9), 2200-2215, 2021 | 71 | 2021 |
A de novo mouse model of C11orf95-RELA fusion-driven ependymoma identifies driver functions in addition to NF-κB T Ozawa, S Arora, F Szulzewsky, G Juric-Sekhar, Y Miyajima, H Bolouri, ... Cell reports 23 (13), 3787-3797, 2018 | 70 | 2018 |
Post-translational modifications of OLIG2 regulate glioma invasion through the TGF-β pathway SK Singh, R Fiorelli, R Kupp, S Rajan, E Szeto, CL Cascio, CL Maire, ... Cell reports 16 (4), 950-966, 2016 | 61 | 2016 |
Lineage-restricted OLIG2-RTK signaling governs the molecular subtype of glioma stem-like cells R Kupp, L Shtayer, AC Tien, E Szeto, N Sanai, DH Rowitch, S Mehta Cell reports 16 (11), 2838-2845, 2016 | 54 | 2016 |
Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion–positive supratentorial ependymomas T Zheng, DR Ghasemi, K Okonechnikov, A Korshunov, M Sill, KK Maass, ... Cancer discovery 11 (9), 2230-2247, 2021 | 53 | 2021 |
ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors R Kupp, L Ruff, S Terranova, E Nathan, S Ballereau, R Stark, ... Cancer discovery 11 (9), 2216-2229, 2021 | 52 | 2021 |
Harnessing OLIG2 function in tumorigenicity and plasticity to target malignant gliomas J Kosty, F Lu, R Kupp, S Mehta, QR Lu Cell Cycle 16 (18), 1654-1660, 2017 | 47 | 2017 |
An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells DH Meijer, Y Sun, T Liu, MF Kane, JA Alberta, G Adelmant, R Kupp, ... Journal of Neuroscience 34 (25), 8507-8518, 2014 | 28 | 2014 |
Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer SA Maisel, D Broka, B Atwell, T Bunch, R Kupp, SK Singh, S Mehta, ... Journal of translational medicine 17, 1-16, 2019 | 20 | 2019 |
Structure–activity relationships of non-opioid [des-Arg7]-dynorphin A analogues for bradykinin receptors YS Lee, D Rankin, SM Hall, C Ramos-Colon, JJ Ortiz, R Kupp, F Porreca, ... Bioorganic & medicinal chemistry letters 24 (21), 4976-4979, 2014 | 13 | 2014 |
Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas. Cancer Discov. 2021 doi: 10.1158/2159-8290 T Zheng, DR Ghasemi, K Okonechnikov, A Korshunov, M Sill, KK Maass, ... CD-20-0963.[Abstract][CrossRef][Google Scholar], 0 | 11 | |
ZFTA-RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma. Cancer Discov A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... | 7 | 2021 |
ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors. Cancer Discov R Kupp, L Ruff, S Terranova, E Nathan, S Ballereau, R Stark, ... | 5 | 2021 |
Various modifications of the amphipathic dynorphin A pharmacophore for rat brain bradykinin receptors YS Lee, R Kupp, MV Remesic, C Ramos‐Colon, SM Hall, C Chan, ... Chemical biology & drug design 88 (4), 615-619, 2016 | 2 | 2016 |
PDTM-45. MECHANISM OF NEURAL STEM CELL TRANSFORMATION BY C11ORF95-RELA TRANSLOCATIONS R Kupp, RJ Gilbertson Neuro-Oncology 21 (Suppl 6), vi197, 2019 | 1 | 2019 |
Molecular Mechanisms of C11orf95 translocations in cancer. R Kupp | | 2020 |
Abstract B20: Targeting Olig2 co-regulators for malignant glioma therapy R Kupp, CL Cascio, F Rauf, D Meijer, CD Stiles, N Sanai, J LaBaer, ... Cancer Research 75 (23_Supplement), B20-B20, 2015 | | 2015 |
CSIG-11OLIG2-MEDIATED REGULATION OF GLIOMA INVASION S Mehta, S Singh, R Fiorelli, R Kupp, CL Cascio, S Rajan, J Yamaguchi, ... Neuro-oncology 17 (Suppl 5), v68, 2015 | | 2015 |