Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells M Borowiak, R Maehr, S Chen, AE Chen, W Tang, JL Fox, SL Schreiber, ... Cell stem cell 4 (4), 348-358, 2009 | 536 | 2009 |
Enantioselective Bromolactonization of Conjugated (Z)-Enynes W Zhang, S Zheng, N Liu, JB Werness, IA Guzei, W Tang Journal of the American Chemical Society 132 (11), 3664-3665, 2010 | 343 | 2010 |
Divergent enantioselective synthesis of (−)-galanthamine and (−)-morphine BM Trost, W Tang, FD Toste Journal of the American Chemical Society 127 (42), 14785-14803, 2005 | 262 | 2005 |
Transition metal-catalyzed selective carbon–carbon bond cleavage of vinylcyclopropanes in cycloaddition reactions J Wang, SA Blaszczyk, X Li, W Tang Chemical reviews 121 (1), 110-139, 2020 | 193 | 2020 |
Enantioselective synthesis of (−)-codeine and (−)-morphine BM Trost, W Tang Journal of the American Chemical Society 124 (49), 14542-14543, 2002 | 174 | 2002 |
Development of the first small molecule histone deacetylase 6 (HDAC6) degraders K Yang, Y Song, H Xie, H Wu, YT Wu, ED Leisten, W Tang Bioorganic & medicinal chemistry letters 28 (14), 2493-2497, 2018 | 171 | 2018 |
Neuroendocrine tumor‐targeted upconversion nanoparticle‐based micelles for simultaneous nir‐controlled combination chemotherapy and photodynamic therapy, and fluorescence imaging G Chen, R Jaskula‐Sztul, CR Esquibel, I Lou, Q Zheng, A Dammalapati, ... Advanced functional materials 27 (8), 1604671, 2017 | 170 | 2017 |
Rhodium-catalyzed acyloxy migration of propargylic esters in cycloadditions, inspiration from the recent “gold rush” XZ Shu, D Shu, CM Schienebeck, W Tang Chemical Society Reviews 41 (23), 7698-7711, 2012 | 170 | 2012 |
Generation of rhodium (I) carbenes from ynamides and their reactions with alkynes and alkenes R Liu, GN Winston-McPherson, ZY Yang, X Zhou, W Song, IA Guzei, X Xu, ... Journal of the American Chemical Society 135 (22), 8201-8204, 2013 | 146 | 2013 |
Development of multifunctional histone deacetylase 6 degraders with potent antimyeloma activity H Wu, K Yang, Z Zhang, ED Leisten, Z Li, H Xie, J Liu, KA Smith, ... Journal of medicinal chemistry 62 (15), 7042-7057, 2019 | 145 | 2019 |
A marine microbiome antifungal targets urgent-threat drug-resistant fungi F Zhang, M Zhao, DR Braun, SS Ericksen, JS Piotrowski, J Nelson, ... Science 370 (6519), 974-978, 2020 | 137 | 2020 |
DABCO-catalyzed 1, 4-bromolactonization of conjugated enynes: highly stereoselective formation of a stereogenic center and an axially chiral allene W Zhang, H Xu, H Xu, W Tang Journal of the American Chemical Society 131 (11), 3832-3833, 2009 | 137 | 2009 |
Cinchona alkaloids as organocatalysts in enantioselective halofunctionalization of alkenes and alkynes S Zheng, CM Schienebeck, W Zhang, HY Wang, W Tang Asian Journal of Organic Chemistry 3 (4), 366-376, 2014 | 133 | 2014 |
Stereoselective total synthesis of hainanolidol and harringtonolide via oxidopyrylium-based [5+ 2] cycloaddition M Zhang, N Liu, W Tang Journal of the American Chemical Society 135 (33), 12434-12438, 2013 | 131 | 2013 |
Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR) SH Seok, ZX Ma, JB Feltenberger, H Chen, H Chen, C Scarlett, Z Lin, ... Journal of Biological Chemistry 293 (6), 1994-2005, 2018 | 128 | 2018 |
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma T Hideshima, J Qi, RM Paranal, W Tang, E Greenberg, N West, ... Proceedings of the National Academy of Sciences 113 (46), 13162-13167, 2016 | 128 | 2016 |
Synthesis of naturally occurring tropones and tropolones N Liu, W Song, CM Schienebeck, M Zhang, W Tang Tetrahedron 70 (49), 9281-9305, 2014 | 117 | 2014 |
Development of triantennary N-acetylgalactosamine conjugates as degraders for extracellular proteins Y Zhou, P Teng, NT Montgomery, X Li, W Tang ACS Central Science 7 (3), 499-506, 2021 | 115 | 2021 |
An Efficient Enantioselective Synthesis of (−)‐Galanthamine BM Trost, W Tang Angewandte Chemie International Edition 41 (15), 2795-2797, 2002 | 112 | 2002 |
Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity DM Fass, SA Reis, B Ghosh, KM Hennig, NF Joseph, WN Zhao, ... Neuropharmacology 64, 81-96, 2013 | 111 | 2013 |