关注
Ashleigh Shannon
Ashleigh Shannon
AFMB and CNRS
在 univ-amu.fr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
A Shannon, NTT Le, B Selisko, C Eydoux, K Alvarez, JC Guillemot, ...
Antiviral research 178, 104793, 2020
3372020
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
A Shannon, B Selisko, NTT Le, J Huchting, F Touret, G Piorkowski, ...
Nature communications 11 (1), 4682, 2020
2342020
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
A Shannon, B Selisko, NTT Le, J Huchting, F Touret, G Piorkowski, ...
BioRxiv, 2020
1122020
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
A Shannon, V Fattorini, B Sama, B Selisko, M Feracci, C Falcou, P Gauffre, ...
Nature Communications 13 (1), 621, 2022
672022
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
M Seifert, SC Bera, P Van Nies, RN Kirchdoerfer, A Shannon, TTN Le, ...
Elife 10, e70968, 2021
622021
Drugs against SARS‐CoV‐2: What do we know about their mode of action?
C Valle, B Martin, F Touret, A Shannon, B Canard, JC Guillemot, ...
Reviews in medical virology 30 (6), 1-10, 2020
432020
Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain
AE Shannon, KJ Chappell, MJ Stoermer, SY Chow, WM Kok, DP Fairlie, ...
Protein expression and purification 119, 124-129, 2016
292016
Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays
DA Muller, ACI Depelsenaire, AE Shannon, D Watterson, SR Corrie, ...
Vaccines 7 (4), 189, 2019
282019
Evaluation of AT-752, a Double Prodrug of a Guanosine Nucleotide Analog with In Vitro and In Vivo Activity against Dengue and Other Flaviviruses
SS Good, A Shannon, K Lin, A Moussa, JG Julander, P La Colla, G Collu, ...
Antimicrobial agents and chemotherapy 65 (11), 10.1128/aac. 00988-21, 2021
262021
Kill or corrupt: Mechanisms of action and drug-resistance of nucleotide analogues against SARS-CoV-2
A Shannon, B Canard
Antiviral Research 210, 105501, 2023
182023
A fluorescence-based high throughput-screening assay for the SARS-CoV RNA synthesis complex
C Eydoux, V Fattorini, A Shannon, B Didier, B Canard, JC Guillemot
Journal of Virological Methods 288, 114013, 2021
182021
Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527
A Shannon, V Fattorini, B Sama, B Selisko, M Feracci, C Falcou, P Gauffre, ...
BioRxiv, 2021.03. 23.436564, 2021
162021
Signatures and mechanisms of efficacious therapeutic ribonucleotides against SARS-CoV-2 revealed by analysis of its replicase using magnetic tweezers
M Seifert, SC Bera, P van Nies, RN Kirchdoerfer, A Shannon, X Meng, ...
132020
Product release is rate-limiting for catalytic processing by the Dengue virus protease
AE Shannon, MM Pedroso, KJ Chappell, D Watterson, S Liebscher, ...
Scientific Reports 6 (1), 37539, 2016
112016
A N7-guanine RNA cap methyltransferase signature-sequence as a genetic marker of large genome, non-mammalian Tobaniviridae
F Ferron, HJ Debat, A Shannon, E Decroly, B Canard
NAR Genomics and Bioinformatics 2 (1), lqz022, 2020
82020
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5
M Feracci, C Eydoux, V Fattorini, LL Bello, P Gauffre, B Selisko, ...
Antiviral research 212, 105574, 2023
62023
Structure and sequence requirements for RNA capping at the venezuelan equine encephalitis virus RNA 5′ end
O Ortega Granda, C Valle, A Shannon, E Decroly, B Canard, B Coutard, ...
Journal of virology 95 (15), 10.1128/jvi. 00777-21, 2021
52021
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome
A Shannon, B Sama, P Gauffre, T Guez, F Debart, JJ Vasseur, E Decroly, ...
Nucleic Acids Research 50 (19), 11186-11198, 2022
32022
An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex
A Shannon, A Chazot, M Feracci, C Falcou, V Fattorini, B Selisko, S Good, ...
Nucleic Acids Research 52 (3), 1325-1340, 2024
12024
Niran interfering drugs for sars-cov-2 mutant therapy
JP Sommadossi, K Lin, A Moussa, B Canard, A Shannon
US Patent App. 18/132,300, 2023
12023
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