Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy ND Jayaraj, BJ Bhattacharyya, AA Belmadani, D Ren, CA Rathwell, ... The Journal of clinical investigation 128 (6), 2205-2225, 2018 | 86 | 2018 |
Mitochondrial calcium uniporter deletion prevents painful diabetic neuropathy by restoring mitochondrial morphology and dynamics DS George, S Hackelberg, ND Jayaraj, D Ren, SL Edassery, CA Rathwell, ... Pain 163 (3), 560-578, 2022 | 34 | 2022 |
Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice DM Menichella, ND Jayaraj, HM Wilson, D Ren, K Flood, XQ Wang, ... Molecular Pain 12, 1744806916666284, 2016 | 26 | 2016 |
Misregulation of mitochondria–lysosome contact dynamics in Charcot–Marie–Tooth Type 2B disease Rab7 mutant sensory peripheral neurons YC Wong, ND Jayaraj, TB Belton, GC Shum, HE Ball, D Ren, ... Proceedings of the National Academy of Sciences 120 (44), e2313010120, 2023 | 8 | 2023 |
A subpopulation of peripheral sensory neurons expressing the Mas-related G Protein-Coupled Receptor d (Mrgprd) generates pain hypersensitivity in painful diabetic neuropathy DS George, ND Jayaraj, D Ren, RE Miller, AM Malfait, RJ Miller, ... bioRxiv, 2022.10. 27.514066, 2022 | 4 | 2022 |
The Mas-related G protein–coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy DS George, ND Jayaraj, P Pacifico, D Ren, N Sriram, RE Miller, ... Pain, 10.1097, 2022 | 4 | 2022 |
Keratinocyte-derived exosomes in painful diabetic neuropathy J Coy-Dibley, ND Jayaraj, D Ren, P Pacifico, A Belmadani, YZ Wang, ... bioRxiv, 2024 | 2 | 2024 |
Integrating sensory neurons with keratinocytes to model painful diabetic neuropathy on a Chip A Belamadni, D Ren, N Jayaraj, D George, R Miller, D Mencihella The Journal of Pain 23 (5), 10, 2022 | 2 | 2022 |
Activation of Keratinocyte Gq-linked G-Protein Coupled Receptors Regulates Degeneration of Cutaneous Nerves A Belmadani, ND Jayaraj, DS George, D Ren, C Rathwell, RJ Miller, ... The Journal of Pain 22 (5), 581, 2021 | 1 | 2021 |
Epidermal Langerhans Cells Drive Painful Diabetic Neuropathy in a Sex-dependent Manner P Pacifico, D George, N Jayaraj, D Ren, J Coy-Dibley, A Belmadani, ... bioRxiv, 2025.01. 30.635734, 2025 | | 2025 |
Keratinocyte-derived extracellular vesicles in painful diabetic neuropathy J Coy-Dibley, ND Jayaraj, D Ren, P Pacifico, A Belmadani, YZ Wang, ... Neurobiology of Pain 17, 100176, 2025 | | 2025 |
Epidermal Langerhans Cells Drive Painful Diabetic Neuropathy through Neuro Immune-Mediated Mechanisms P Pacifico, ND Jayaraj, D Ren, D George, JS Coy-Dibley, M Andelic, ... ANNALS OF NEUROLOGY 96, S209-S209, 2024 | | 2024 |
Single Cell Transcriptomics of Mouse Epidermis Reveals a Pivotal Role of Langerhans Cells in Painful Diabetic Neuropathy P Pacifico, ND Jayaraj, D Ren, JS Coy-Dibley, AA Belmadani, D George, ... The Journal of Pain 25 (4), 21, 2024 | | 2024 |
Uncovering Mechanisms Of Cutaneous Denervation In Painful Diabetic Neuropathy Using An Unbiased Single-Cell Transcriptional Approach P Pacifico, ND Jayaraj, D Ren, AA Belmadani, D George, RJ Miller, ... The Journal of Pain 24 (4), 39-40, 2023 | | 2023 |
Activation Of Keratinocyte Gq-Linked G-Protein Coupled Receptors Enhances Dorsal Root Ganglion Neuron Voltage-Gated Sodium Channel Activity And Neuronal Excitability A Belamadni, D Ren, N Jayaraj, RJ Miller, CG Vanoye, AL George, ... The Journal of Pain 24 (4), 4-5, 2023 | | 2023 |
ACTIVATION OF KERATINOCYTE GQ-LINKED G-PROTEIN COUPLED RECEPTORS REMODELS DORSAL ROOT GANGLION NEURONS SINGLE-CELL TRANSCRIPTOMIC PROFILE A Belmadani, D George, N Jayaraj, D Ren, R Miller, D Menichella JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 27, S15-S15, 2022 | | 2022 |
INTEGRATING SENSORY NEURONS WITH KERATINOCYTES TO MODEL PAINFUL DIABETIC NEUROPATHY ON A CHIP A Belmadani, D Ren, N Jayaraj, D George, R Miller, D Menichella JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 27, S157-S157, 2022 | | 2022 |
Activation of Keratinocyte Gq-linked G-Protein Coupled Receptors Remodels Dorsal Root Ganglion Neurons Single-Cell Transcriptomic Profile D George, A Belmadani, ND Jayaraj, D Ren, R Miller, DD Menichella The Journal of Pain 23 (5), 37, 2022 | | 2022 |
Neuron-Keratinocyte Communication in the Epidermis in Painful Diabetic Neuropathy DS George, ND Jayaraj, A Belmadani, D Ren, R Miller, D Menichella The Journal of Pain 23 (5), 37, 2022 | | 2022 |
Gq-Linked G-Protein Coupled Receptors Signaling in Keratinocytes Regulates Degeneration of Cutaneous Nerves A Belmadani, DS George, ND Jayaraj, CA Rathwell, D Ren, RJ Miller, ... ANNALS OF NEUROLOGY 90, S236-S237, 2021 | | 2021 |