Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery PS Chahal, E Schulze, R Tran, J Montes, AA Kamen Journal of virological methods 196, 163-173, 2014 | 113 | 2014 |
Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells Y Durocher, PL Pham, G St-Laurent, D Jacob, B Cass, P Chahal, CJ Lau, ... Journal of virological methods 144 (1-2), 32-40, 2007 | 113 | 2007 |
Production of recombinant adeno‐associated viral vectors using a baculovirus/insect cell suspension culture system: From shake flasks to a 20‐L bioreactor J Meghrous, MG Aucoin, D Jacob, PS Chahal, N Arcand, AA Kamen Biotechnology progress 21 (1), 154-160, 2005 | 95 | 2005 |
Manufacturing of recombinant adeno‐associated viruses using mammalian expression platforms MA Robert, PS Chahal, A Audy, A Kamen, R Gilbert, B Gaillet Biotechnology journal 12 (3), 1600193, 2017 | 93 | 2017 |
Production of Cellulase in Solid-State Fermentation with Trichoderma reesei MCG 80 on Wheat Straw PS Chahal, DS Chahal, GBB Lê Seventeenth Symposium on Biotechnology for Fuels and Chemicals: Presented as …, 1996 | 89 | 1996 |
Primary recovery and chromatographic purification of adeno-associated virus type 2 produced by baculovirus/insect cell system PS Chahal, MG Aucoin, A Kamen Journal of virological methods 139 (1), 61-70, 2007 | 76 | 2007 |
Hemagglutinin and neuraminidase containing virus-like particles produced in HEK-293 suspension culture: An effective influenza vaccine candidate A Venereo-Sanchez, R Gilbert, M Simoneau, A Caron, P Chahal, W Chen, ... Vaccine 34 (29), 3371-3380, 2016 | 61 | 2016 |
Manufacturing of viral vectors for gene therapy: part I. Upstream processing OW Merten, M Schweizer, P Chahal, AA Kamen Pharm Bioprocess 2 (2), 183-203, 2014 | 56 | 2014 |
Cellulase production profile of Trichoderma reesei on different cellulosic substrates at various pH levels PS Chahal, DS Chahal, G André Journal of fermentation and bioengineering 74 (2), 126-128, 1992 | 55 | 1992 |
Achieving high-yield production of functional AAV5 gene delivery vectors via fedbatch in an insect cell-one baculovirus system PRH Joshi, L Cervera, I Ahmed, O Kondratov, S Zolotukhin, J Schrag, ... Molecular Therapy-Methods & Clinical Development 13, 279-289, 2019 | 50 | 2019 |
A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis W Shao, A Paul, S Abbasi, PS Chahal, JA Mena, J Montes, A Kamen, ... International journal of nanomedicine, 1575-1586, 2012 | 49 | 2012 |
Manufacturing of viral vectors: Part II. Downstream processing and safety aspects OW Merten, M Schweizer, P Chahal, AA Kamen Pharma. Bioprocess. 2 (3), 237-251, 2014 | 45 | 2014 |
Improving adeno‐associated vector yield in high density insect cell cultures JA Mena, MG Aucoin, J Montes, PS Chahal, AA Kamen The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2010 | 45 | 2010 |
Development of a scalable and robust AEX method for enriched rAAV preparations in genome-containing VCs of serotypes 5, 6, 8, and 9 PRH Joshi, A Bernier, PD Moço, J Schrag, PS Chahal, A Kamen Molecular Therapy-Methods & Clinical Development 21, 341-356, 2021 | 44 | 2021 |
Advancements in molecular design and bioprocessing of recombinant adeno‐associated virus gene delivery vectors using the insect‐cell baculovirus expression platform PRH Joshi, A Venereo‐Sanchez, PS Chahal, AA Kamen Biotechnology Journal 16 (4), 2000021, 2021 | 41 | 2021 |
Validation of a high-performance liquid chromatographic assay for the quantification of adenovirus type 5 particles J Transfiguracion, A Bernier, N Arcand, P Chahal, A Kamen Journal of Chromatography B: Biomedical Sciences and Applications 761 (2 …, 2001 | 40 | 2001 |
Virus-like particle and viral vector production using the baculovirus expression vector system/insect cell system: adeno-associated virus-based products MG Aucoin, D Jacob, PS Chahal, J Meghrous, A Bernier, AA Kamen Baculovirus and Insect Cell Expression Protocols, 281-296, 2007 | 34 | 2007 |
Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line A Venereo-Sanchez, M Simoneau, S Lanthier, P Chahal, L Bourget, ... Vaccine 35 (33), 4220-4228, 2017 | 31 | 2017 |
Lignocellulosic wastes: biological conversion PS Chahal, DS Chahal Bioconversion of waste materials to industrial products, 376-422, 1998 | 31 | 1998 |
Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells JF Gélinas, H Azizi, S Kiesslich, S Lanthier, J Perdersen, PS Chahal, ... Vaccine 37 (44), 6624-6632, 2019 | 30 | 2019 |