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Margherita Norelli
Margherita Norelli
Senior Scientist, 2Seventy bio
在 2seventybio.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
M Norelli, B Camisa, G Barbiera, L Falcone, A Purevdorj, M Genua, ...
Nature medicine 24 (6), 739-748, 2018
13002018
CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma
M Casucci, B Nicolis di Robilant, L Falcone, B Camisa, M Norelli, ...
Blood, The Journal of the American Society of Hematology 122 (20), 3461-3472, 2013
4012013
Extracellular NGFR spacers allow efficient tracking and enrichment of fully functional CAR-T cells co-expressing a suicide gene
M Casucci, L Falcone, B Camisa, M Norelli, S Porcellini, A Stornaiuolo, ...
Frontiers in immunology 9, 507, 2018
932018
Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens
G Escobar, L Barbarossa, G Barbiera, M Norelli, M Genua, A Ranghetti, ...
Nature Communications 9 (1), 2896, 2018
572018
Clinical pharmacology of CAR-T cells: Linking cellular pharmacodynamics to pharmacokinetics and antitumor effects
M Norelli, M Casucci, C Bonini, A Bondanza
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1865 (1), 90-100, 2016
472016
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, ...
Nature Communications 12 (1), 4559, 2021
262021
Modeling human graft-versus-host disease in immunocompromised mice
M Norelli, B Camisa, A Bondanza
Tumor Immunology: Methods and Protocols, 127-132, 2016
52016
myeloid leukemia and multiple myeloma CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma
M Casucci, B Nicolis, L Falcone, B Camisa, M Norelli, P Genovese
Blood 122, 3461-3472, 2013
42013
Monocyte-Derived IL-1 and IL-6 are Differentially Required for Cytokine Release Syndrome and Neurotoxicity by CAR-T Cells
M Norelli, B Camisa, G Barbiera, L Falcone, A Purevdorj, M Genua, ...
MOLECULAR THERAPY 26 (5), 10-11, 2018
22018
Off-tumor target expression levels do not predict CAR-T cell killing: a foundation for the safety of CD44v6-targeted T cells
M Casucci, BN di Robilant, L Falcone, B Camisa, M Norelli, B Gentner, ...
Blood 122 (21), 142, 2013
22013
Monocytes are required for both optimal anti-leukemic efficacy and the cytokine release syndrome by CAR-T cells: lessons from an innovative xenotolerant mouse model
M Norelli, M Casucci, B Camisa, L Falcone, C Traversari, C Bordignon, ...
Blood 128 (22), 997, 2016
12016
Il-1 antagonist and toxicity induced by cell therapy
A Bondanza, B Camisa, M Norelli
US Patent App. 16/978,897, 2021
2021
Il-1 antagonist and toxicity induced by cell therapy
A Bondanza, B CAMISA, M NORELLI
2021
Oncogene-induced senescence in haematopoietic progenitors features myeloid-restricted hematopoiesis and histiocytosis
R Biavasco, E Lettera, M Norelli, B Camisa, D Cesana, P Gallina, ...
HUMAN GENE THERAPY 29 (12), A37-A37, 2018
2018
Oncogene-Induced Senescence in Hematopoietic Progenitors Leads to Myeloid-Restricted Hematopoiesis, Chronic Inflammation and Histiocytosis
R Biavasco, E Lettera, M Norelli, B Camisa, D Cesana, P Gallina, ...
MOLECULAR THERAPY 26 (5), 372-372, 2018
2018
BRAFV600E expression in haematopoietic progenitors leads to senescence, myeloid skewing and aggressive histiocytosis
R Biavasco, E Lettera, M Norelli, B Camisa, D Cesana, P Gallina, ...
HUMAN GENE THERAPY 28 (12), A19-A19, 2017
2017
MONOCYTES ARE REQUIRED FOR BOTH OPTIMAL ANTI-LEUKEMIC EFFICACY AND RELATED TOXICITIES BY CAR-T CELLS
M Norelli, M Casucci, B Camisa, L Falcone, C Traversari, C Bordignon, ...
HAEMATOLOGICA 102, 7-7, 2017
2017
OP0179 Brafv600e promotes myeloid skewing in multisystemic langerhans cell histiocytosis humanized mouse model
R Biavasco, M Norelli, B Camisa, D Cesana, P Gallina, B Gentner, ...
Annals of the Rheumatic Diseases 76 (Suppl 2), 126-126, 2017
2017
Modeling the cytokine release syndrome and its treatment in a long-term xenotolerant mouse model of CAR-T cell immunotherapy
M Norelli, M Casucci, B Camisa, L Falcone, A Saudemont, F Ciceri, ...
HUMAN GENE THERAPY 27 (11), A31-A31, 2016
2016
512. The Cytokine Release Syndrome Crucially Contributes to the Anti-Leukemic Effects of CD44v6 CAR-T Cells
M Norelli, M Casucci, B Camisa, L Falcone, A Saudemont, L Naldini, ...
Molecular Therapy 24, S204, 2016
2016
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