Broadly neutralizing antibodies target a haemagglutinin anchor epitope JJ Guthmiller, J Han, HA Utset, L Li, LYL Lan, C Henry, CT Stamper, ... Nature 602 (7896), 314-320, 2022 | 84 | 2022 |
Characterizing the diversity of the CDR-H3 loop conformational ensembles in relationship to antibody binding properties ML Fernández-Quintero, JR Loeffler, J Kraml, U Kahler, AS Kamenik, ... Frontiers in immunology 9, 3065, 2019 | 81 | 2019 |
Polyreactive broadly neutralizing B cells are selected to provide defense against pandemic threat influenza viruses JJ Guthmiller, LYL Lan, ML Fernández-Quintero, J Han, HA Utset, DJ Bitar, ... Immunity 53 (6), 1230-1244. e5, 2020 | 73 | 2020 |
CDR-H3 loop ensemble in solution–conformational selection upon antibody binding ML Fernández-Quintero, J Kraml, G Georges, KR Liedl MAbs 11 (6), 1077-1088, 2019 | 51 | 2019 |
Antibodies exhibit multiple paratope states influencing VH–VL domain orientations ML Fernández-Quintero, ND Pomarici, BA Math, KB Kroell, F Waibl, ... Communications biology 3 (1), 589, 2020 | 44 | 2020 |
Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder NT Hofer, P Tuluc, NJ Ortner, YV Nikonishyna, ML Fernándes-Quintero, ... Molecular autism 11, 1-18, 2020 | 40 | 2020 |
Local and global rigidification upon antibody affinity maturation ML Fernández-Quintero, JR Loeffler, LM Bacher, F Waibl, CA Seidler, ... Frontiers in molecular biosciences 7, 182, 2020 | 36 | 2020 |
CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders Y El Ghaleb, PE Schneeberger, ML Fernández-Quintero, SM Geisler, ... Brain 144 (7), 2092-2106, 2021 | 33 | 2021 |
VH‐VL interdomain dynamics observed by computer simulations and NMR ML Fernández‐Quintero, VJ Hoerschinger, LM Lamp, A Bujotzek, ... Proteins: Structure, Function, and Bioinformatics 88 (7), 830-839, 2020 | 30 | 2020 |
Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures ML Fernández-Quintero, MC Heiss, ND Pomarici, BA Math, KR Liedl MAbs 12 (1), 1744328, 2020 | 30 | 2020 |
Structural determinants of voltage-gating properties in calcium channels ML Fernández-Quintero, Y El Ghaleb, P Tuluc, M Campiglio, KR Liedl, ... Elife 10, e64087, 2021 | 28 | 2021 |
Assessing developability early in the discovery process for novel biologics ML Fernández-Quintero, A Ljungars, F Waibl, V Greiff, JT Andersen, ... MAbs 15 (1), 2171248, 2023 | 26 | 2023 |
Mutation of framework residue H71 results in different antibody paratope states in solution ML Fernández-Quintero, KB Kroell, F Hofer, JR Riccabona, KR Liedl Frontiers in Immunology 12, 630034, 2021 | 26 | 2021 |
Conformational ensembles of antibodies determine their hydrophobicity F Waibl, ML Fernández-Quintero, AS Kamenik, J Kraml, F Hofer, ... Biophysical Journal 120 (1), 143-157, 2021 | 25 | 2021 |
T-cell receptor CDR3 loop conformations in solution shift the relative VH-VL domain distributions ML Fernández-Quintero, ND Pomarici, JR Loeffler, CA Seidler, KR Liedl Frontiers in Immunology 11, 1440, 2020 | 25 | 2020 |
Challenges in antibody structure prediction ML Fernández-Quintero, J Kokot, F Waibl, ALM Fischer, PK Quoika, ... MAbs 15 (1), 2175319, 2023 | 22 | 2023 |
Ensembles in solution as a new paradigm for antibody structure prediction and design ML Fernández-Quintero, G Georges, JM Varga, KR Liedl MAbs 13 (1), 1923122, 2021 | 22 | 2021 |
Cav1. 4 dysfunction and congenital stationary night blindness type 2 A Koschak, ML Fernandez-Quintero, T Heigl, M Ruzza, H Seitter, L Zanetti Pflügers Archiv-European Journal of Physiology 473 (9), 1437-1454, 2021 | 21 | 2021 |
Transitions of CDR-L3 loop canonical cluster conformations on the micro-to-millisecond timescale ML Fernández-Quintero, BA Math, JR Loeffler, KR Liedl Frontiers in immunology 10, 2652, 2019 | 20 | 2019 |
Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes ML Fernández-Quintero, JR Loeffler, F Waibl, AS Kamenik, F Hofer, ... Protein Engineering, Design and Selection 32 (11), 513-523, 2019 | 20 | 2019 |