| The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity N Barretto, D Jukneliene, K Ratia, Z Chen, AD Mesecar, SC Baker Journal of virology 79 (24), 15189-15198, 2005 | 605 | 2005 |
| A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 494 | 2008 |
| Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme K Ratia, KS Saikatendu, BD Santarsiero, N Barretto, SC Baker, ... Proceedings of the National Academy of Sciences 103 (15), 5717-5722, 2006 | 453 | 2006 |
| Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling M Frieman, K Ratia, RE Johnston, AD Mesecar, RS Baric Journal of virology 83 (13), 6689-6705, 2009 | 409 | 2009 |
| Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases MA Clementz, Z Chen, BS Banach, Y Wang, L Sun, K Ratia, ... Journal of virology 84 (9), 4619-4629, 2010 | 355 | 2010 |
| Structural basis for the ubiquitin-linkage specificity and deISGylating activity of SARS-CoV papain-like protease K Ratia, A Kilianski, YM Baez-Santos, SC Baker, A Mesecar PLoS pathogens 10 (5), e1004113, 2014 | 227 | 2014 |
| Pleiotropic mechanisms facilitated by resveratrol and its metabolites B Calamini, K Ratia, MG Malkowski, M Cuendet, JM Pezzuto, ... Biochemical Journal 429 (2), 273-282, 2010 | 210 | 2010 |
| Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery V Grum-Tokars, K Ratia, A Begaye, SC Baker, AD Mesecar Virus research 133 (1), 63-73, 2008 | 197 | 2008 |
| Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein− ligand X-ray structure and biological evaluation AK Ghosh, J Takayama, KV Rao, K Ratia, R Chaudhuri, DC Mulhearn, ... Journal of medicinal chemistry 53 (13), 4968-4979, 2010 | 168 | 2010 |
| Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors AK Ghosh, K Xi, K Ratia, BD Santarsiero, W Fu, BH Harcourt, PA Rota, ... Journal of medicinal chemistry 48 (22), 6767-6771, 2005 | 159 | 2005 |
| Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome− coronavirus papain-like … AK Ghosh, J Takayama, Y Aubin, K Ratia, R Chaudhuri, Y Baez, ... Journal of medicinal chemistry 52 (16), 5228-5240, 2009 | 141 | 2009 |
| Design of SARS-CoV-2 PLpro inhibitors for COVID-19 antiviral therapy leveraging binding cooperativity Z Shen, K Ratia, L Cooper, D Kong, H Lee, Y Kwon, Y Li, S Alqarni, ... Journal of medicinal chemistry 65 (4), 2940-2955, 2021 | 129 | 2021 |
| Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63 Z Chen, Y Wang, K Ratia, AD Mesecar, KD Wilkinson, SC Baker Journal of virology 81 (11), 6007-6018, 2007 | 124 | 2007 |
| Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high … HA Elshabrawy, J Fan, CS Haddad, K Ratia, CC Broder, M Caffrey, ... Journal of virology 88 (8), 4353-4365, 2014 | 121 | 2014 |
| Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors AK Ghosh, K Xi, V Grum-Tokars, X Xu, K Ratia, W Fu, KV Houser, ... Bioorganic & medicinal chemistry letters 17 (21), 5876-5880, 2007 | 115 | 2007 |
| Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans R Hawwa, SD Larsen, K Ratia, AD Mesecar Journal of molecular biology 393 (1), 36-57, 2009 | 90 | 2009 |
| A comparative high-throughput screening protocol to identify entry inhibitors of enveloped viruses J Wang, H Cheng, K Ratia, E Varhegyi, WG Hendrickson, J Li, L Rong Journal of biomolecular screening 19 (1), 100-107, 2014 | 53 | 2014 |
| Deubiquitinating activity of the SARS-CoV papain-like protease N Barretto, D Jukneliene, K Ratia, Z Chen, AD Mesecar, SC Baker The Nidoviruses: Toward Control of SARS and other Nidovirus Diseases, 37-41, 2006 | 50 | 2006 |
| Hit-to-Lead: hit validation and assessment KE Hevener, R Pesavento, JH Ren, H Lee, K Ratia, ME Johnson Methods in Enzymology 610, 265-309, 2018 | 43 | 2018 |
| Isoquinoline Kelch-like ECH-associated protein 1-nuclear factor (erythroid-derived 2)-like 2 (KEAP1-NRF2) inhibitors with high metabolic stability PR Lazzara, BP David, A Ankireddy, BG Richardson, K Dye, KM Ratia, ... Journal of medicinal chemistry 63 (12), 6547-6560, 2019 | 42 | 2019 |
