Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives J Dumont, D Euwart, B Mei, S Estes, R Kshirsagar Critical reviews in biotechnology 36 (6), 1110-1122, 2016 | 601 | 2016 |
E2F activity is regulated by cell cycle-dependent changes in subcellular localization R Verona, K Moberg, S Estes, M Starz, JP Vernon, JA Lees Molecular and cellular biology 17 (12), 7268-7282, 1997 | 291 | 1997 |
Tumors associated with oncogenic osteomalacia express genes important in bone and mineral metabolism SMJ De Beur, RB Finnegan, J Vassiliadis, B Cook, D Barberio, S Estes, ... Journal of Bone and Mineral Research 17 (6), 1102-1110, 2002 | 249 | 2002 |
Development of a simple and rapid method for producing non‐fucosylated oligomannose containing antibodies with increased effector function Q Zhou, S Shankara, A Roy, H Qiu, S Estes, A McVie‐Wylie, ... Biotechnology and Bioengineering 99 (3), 652-665, 2008 | 247 | 2008 |
A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties K Dooley, RE McConnell, K Xu, ND Lewis, S Haupt, MR Youniss, S Martin, ... Molecular therapy 29 (5), 1729-1743, 2021 | 207 | 2021 |
Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine H Qiu, T Edmunds, J Baker-Malcolm, KP Karey, S Estes, C Schwarz, ... Journal of Biological Chemistry 278 (35), 32744-32752, 2003 | 163 | 2003 |
Accelerated clone selection for recombinant CHO cells using a FACS‐based high‐throughput screen CT DeMaria, V Cairns, C Schwarz, J Zhang, M Guerin, E Zuena, S Estes, ... Biotechnology progress 23 (2), 465-472, 2007 | 117 | 2007 |
Industry view on the relative importance of “clonality” of biopharmaceutical-producing cell lines C Frye, R Deshpande, S Estes, K Francissen, J Joly, A Lubiniecki, ... Biologicals 44 (2), 117-122, 2016 | 108 | 2016 |
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance SC Jang, KD Economides, RJ Moniz, CL Sia, N Lewis, C McCoy, T Zi, ... Communications biology 4 (1), 497, 2021 | 107 | 2021 |
Mammalian cell line developments in speed and efficiency S Estes, M Melville Mammalian cell cultures for biologics manufacturing, 11-33, 2014 | 88 | 2014 |
Integrated cell and process engineering for improved transient production of a “difficult‐to‐express “fusion protein by CHO cells YB Johari, SD Estes, CS Alves, MS Sinacore, DC James Biotechnology and Bioengineering 112 (12), 2527-2542, 2015 | 86 | 2015 |
Exosome surface display of IL12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared with recombinant IL12 ND Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar, T Zi, K Xu, K Dooley, ... Molecular Cancer Therapeutics 20 (3), 523-534, 2021 | 73 | 2021 |
Normal fibroblasts induce the C/EBPβ and ATF-4 bZIP transcription factors in response to anoxia SD Estes, DL Stoler, GR Anderson Experimental cell research 220 (1), 47-54, 1995 | 63 | 1995 |
Anoxic induction of a sarcoma virus-related VL30 retrotransposon is mediated by a cis-acting element which binds hypoxia-inducible factor 1 and an anoxia-inducible factor SD Estes, DL Stoler, GR Anderson Journal of virology 69 (10), 6335-6341, 1995 | 37 | 1995 |
Manufactured extracellular vesicles as human therapeutics: challenges, advances, and opportunities S Estes, K Konstantinov, JD Young Current Opinion in Biotechnology 77, 102776, 2022 | 32 | 2022 |
Leveraging a CHO cell line toolkit to accelerate biotherapeutics into the clinic C Wright, C Alves, R Kshirsagar, J Pieracci, S Estes Biotechnology Progress 33 (6), 1468-1475, 2017 | 26 | 2017 |
Utilization of non‐AUG initiation codons in a flow cytometric method for efficient selection of recombinant cell lines VR Cairns, CT DeMaria, F Poulin, J Sancho, P Liu, J Zhang, ... Biotechnology and bioengineering 108 (11), 2611-2622, 2011 | 23 | 2011 |
CHO genome mining for synthetic promoter design YB Johari, AJ Brown, CS Alves, Y Zhou, CM Wright, SD Estes, ... Journal of biotechnology 294, 1-13, 2019 | 22 | 2019 |
Genetic mutation analysis at early stages of cell line development using next generation sequencing C Wright, J Groot, S Swahn, H McLaughlin, M Liu, C Xu, C Sun, E Zheng, ... Biotechnology progress 32 (3), 813-817, 2016 | 21 | 2016 |
Integration of cell line and process development to overcome the challenge of a difficult to express protein CS Alves, A Gilbert, S Dalvi, BS Germain, W Xie, S Estes, R Kshirsagar, ... Biotechnology progress 31 (5), 1201-1211, 2015 | 19 | 2015 |