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Chukwunonso Nwabufo
Chukwunonso Nwabufo
PhD Candidate and CIHR Scholar, University of Toronto; Founder and CEO, OneDrug Inc.
在 mail.utoronto.ca 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Pharmacogenomics in the era of next generation sequencing–from byte to bedside
LE Russell, Y Zhou, AA Almousa, JK Sodhi, CK Nwabufo, VM Lauschke
Drug Metabolism Reviews 53 (2), 253-278, 2021
302021
Diagnostic and therapeutic agents that target alpha-synuclein in Parkinson’s disease
CK Nwabufo, OP Aigbogun
Journal of neurology 269 (11), 5762-5786, 2022
152022
Relevance of ABC transporters in drug development
CK Nwabufo
Current Drug Metabolism 23 (6), 434-446, 2022
102022
Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds
CK Nwabufo, OP Aigbogun, KJH Allen, MN Owens, JS Lee, CP Phenix, ...
Xenobiotica 51 (8), 885-900, 2021
102021
Bioanalytical strategies in drug discovery and development
A Thakur, Z Tan, T Kameyama, E El-Khateeb, S Nagpal, S Malone, ...
Drug Metabolism Reviews 53 (3), 434-458, 2021
102021
Advances in the study of drug metabolism–symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX)
LE Russell, MA Schleiff, E Gonzalez, AG Bart, F Broccatelli, JH Hartman, ...
Drug metabolism reviews 52 (3), 395-407, 2020
72020
Tandem mass spectrometric analysis of novel caffeine scaffold‐based bifunctional compounds for Parkinson's disease
CK Nwabufo, A El‐Aneed, ES Krol
Rapid communications in mass spectrometry 33 (23), 1792-1803, 2019
72019
Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs
CK Nwabufo, R Bendayan
Trends in Pharmacological Sciences 43 (12), 1041-1054, 2022
62022
Introduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development
CK Nwabufo
Drug Metabolism Reviews 53 (2), 171-172, 2021
62021
Biochemical effect of Hibiscus sabdariffa Calyx extracts on the reproductive hormones of male Wistar rat
C Nwabufo, O Olusanya
Advances in Applied Science Research 8 (2), 38-41, 2017
62017
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues
CK Nwabufo, MT Hoque, L Yip, M Khara, S Mubareka, MS Pollanen, ...
Frontiers in Pharmacology 14, 1124693, 2023
52023
Mirvetuximab soravtansine in ovarian cancer therapy: expert opinion on pharmacological considerations
CK Nwabufo
Cancer Chemotherapy and Pharmacology 93 (2), 89-105, 2024
42024
Potential application of mass spectrometry imaging in pharmacokinetic studies
CK Nwabufo, OP Aigbogun
Xenobiotica 52 (8), 811-827, 2022
42022
Unraveling the metabolic fate of potential therapeutic dimer compounds for Parkinson’s disease
C Nwabufo, E Krol
Drug Metabolism and Pharmacokinetics 34 (1), S59-S60, 2019
42019
An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds
OP Aigbogun, CK Nwabufo, MN Owens, KJH Allen, JS Lee, CP Phenix, ...
Xenobiotica 52 (8), 916-927, 2022
12022
Healthcare provider and patient perspectives on the implementation of pharmacogenetic-guided treatment in routine clinical practice
G Kaur, CK Nwabufo
Pharmacogenetics and Genomics, 10.1097, 2024
2024
COVID‐19 severity gradient differentially dysregulates clinically relevant drug processing genes in nasopharyngeal swab samples
CK Nwabufo, J Luc, A McGeer, JA Hirota, S Mubareka, AC Doxey, ...
British Journal of Clinical Pharmacology, 2024
2024
Preclinical Development of Novel Bifunctional Compounds for Parkinson's Disease
CK Nwabufo
University of Saskatchewan, 2019
2019
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