关注
Endri Karaj
Endri Karaj
Broad Institute of MIT and Harvard
在 rockets.utoledo.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Tunable Cysteine-Targeting Electrophilic Heteroaromatic Warheads Induce Ferroptosis
E Karaj, SH Sindi, N Kuganesan, L Perera, W Taylor, LMV Tillekeratne
Journal of Medicinal Chemistry 65 (17), 11788–11817, 2022
302022
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics
AA Al-Hamashi, R Koranne, S Dlamini, A Alqahtani, E Karaj, MS Rashid, ...
Bioorganic chemistry 116, 105297, 2021
182021
Photoaffinity Labeling and Bioorthogonal ligation: Two Critical Tools for Designing “Fish Hooks” to Scout for Target Proteins
E Karaj, SH Sindi, LMV Tillekeratne
Bioorganic & Medicinal Chemistry 62, 116721, 2022
132022
First-in-class dual mechanism ferroptosis-HDAC inhibitor hybrids
E Karaj, SH Sindi, N Kuganesan, RA Koranne, JR Knoff, AW James, Y Fu, ...
Journal of medicinal chemistry 65 (21), 14764-14791, 2022
112022
Pharmacophore optimization of imidazole chalcones to modulate microtubule dynamics
E Karaj, S Dlamini, R Koranne, SH Sindi, L Perera, WR Taylor, ...
Bioorganic Chemistry 122, 105700, 2022
82022
Rational design of metabolically stable HDAC inhibitors: An overhaul of trifluoromethyl ketones
B Riddhidev, K Endri, L Sabitri, L N Kotsull, K Nishanth, I Dragan, ...
European journal of medicinal chemistry 244, 114807, 2022
72022
The structural simplification of lysergic acid as a natural lead for synthesizing novel anti-Alzheimer agents
M Alzweiri, AS Alsegiani, E Karaj, DA Almarghalani, Y Tabaza, ZA Shah, ...
Bioorganic & medicinal chemistry letters 47, 128205, 2021
52021
Leveraging multi-mode microextraction and liquid chromatography stationary phases for quantitative analysis of neurotoxin β-N-methylamino-L-alanine and other non-proteinogenic …
RV Emmons, E Karaj, E Cudjoe, DS Bell, LMV Tillekeratne, E Gionfriddo
Journal of Chromatography A 1685, 463636, 2022
42022
Imidazole-based anticancer agents and derivatives thereof, and methods of making and using same
V Tillekeratne, A Al-Hamashi, S Dlamini, ASS Alqahtani, E Karaj
US Patent 11,098,038, 2021
22021
BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF
A CHOUDHARY, S SINGHA, P SINGH, S CHAUDHARY, S Sameek, ...
2024
Metabolically Stable HDAC Inhibitors with Trifluoromethylpyruvamide as Metal-Binding Group
E Karaj, LV Tillekeratne, R Banerjee, WR Taylor
US Patent App. 18/585,551, 2024
2024
CETZOLE Analogs as Potent Ferroptosis Inducers and Their Target Identification Using Covalent/Affinity Probes
S Dlamini, S Mohajeri, N Kuganesan, SH Sindi, E Karaj, DS Rathnayake, ...
Journal of Medicinal Chemistry 67 (18), 16107-16127, 2024
2024
CHIMERIC SMALL MOLECULES FOR LABELING PROTEINS WITH IMMUNOGENIC MOIETIES AND METHODS OF USE THEREOF
A CHOUDHARY, S SINGH, K PAL, E KARAJ, S SINDI, R PERGU, ...
2024
Ferroptosis-HDAC Inhibitor Hybrid Anticancer Agents
V Tillekeratne, E Karaj, S Sindi, W Taylor
US Patent App. 18/238,687, 2024
2024
Medicinal & Chemical Biology Investigation of Ferroptosis Inducers & HDAC Inhibitors
E Karaj
The University of Toledo, 2022
2022
系统目前无法执行此操作,请稍后再试。
文章 1–15