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Matthew J. Harms
Matthew J. Harms
Scribe Therapeutics
在 scribetx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Brown and beige fat: development, function and therapeutic potential
M Harms, P Seale
Nature medicine 19 (10), 1252-1263, 2013
23792013
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice
MJ Harms, J Ishibashi, W Wang, HW Lim, S Goyama, T Sato, M Kurokawa, ...
Cell metabolism 19 (4), 593-604, 2014
4022014
PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program
MJ Harms, HW Lim, Y Ho, SN Shapira, J Ishibashi, S Rajakumari, ...
Genes & development 29 (3), 298-307, 2015
1522015
Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce
Q Li, CE Hagberg, H Silva Cascales, S Lang, MT Hyvönen, F Salehzadeh, ...
Nature medicine 27 (11), 1941-1953, 2021
1222021
EBF2 promotes the recruitment of beige adipocytes in white adipose tissue
RR Stine, SN Shapira, HW Lim, J Ishibashi, M Harms, KJ Won, P Seale
Molecular metabolism 5 (1), 57-65, 2016
1142016
The role of PDE3B phosphorylation in the inhibition of lipolysis by insulin
LM DiPilato, F Ahmad, M Harms, P Seale, V Manganiello, MJ Birnbaum
Molecular and cellular biology 35 (16), 2752-2760, 2015
1112015
Mature human white adipocytes cultured under membranes maintain identity, function, and can transdifferentiate into brown-like adipocytes
MJ Harms, Q Li, S Lee, C Zhang, B Kull, S Hallen, A Thorell, ...
Cell reports 27 (1), 213-225. e5, 2019
1102019
Flow cytometry of mouse and human adipocytes for the analysis of browning and cellular heterogeneity
CE Hagberg, Q Li, M Kutschke, D Bhowmick, E Kiss, IG Shabalina, ...
Cell reports 24 (10), 2746-2756. e5, 2018
932018
ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium
N Gaudreault, N Kumar, JM Posada, KB Stephens, NS Reyes de Mochel, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (2), 264-272, 2012
882012
EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex
SN Shapira, HW Lim, S Rajakumari, AP Sakers, J Ishibashi, MJ Harms, ...
Genes & development 31 (7), 660-673, 2017
752017
PPARγ and PPARα synergize to induce robust browning of white fat in vivo
T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ...
Molecular metabolism 36, 100964, 2020
692020
PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing
M Kissig, J Ishibashi, MJ Harms, HW Lim, RR Stine, KJ Won, P Seale
The EMBO journal 36 (11), 1528-1542, 2017
652017
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity
P Morigny, M Houssier, A Mairal, C Ghilain, E Mouisel, F Benhamed, ...
Nature Metabolism 1 (1), 133-146, 2019
572019
The colorful versatility of adipocytes: white‐to‐brown transdifferentiation and its therapeutic potential in humans
S Maurer, M Harms, J Boucher
The FEBS journal 288 (12), 3628-3646, 2021
512021
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects
V Osinski, DK Bauknight, SSK Dasa, MJ Harms, T Kroon, MA Marshall, ...
Theranostics 10 (2), 585, 2020
222020
New approaches for targeting PCSK9: small-interfering ribonucleic acid and genome editing
RF Oostveen, AV Khera, S Kathiresan, ESG Stroes, K Fitzgerald, ...
Arteriosclerosis, thrombosis, and vascular biology 43 (7), 1081-1092, 2023
162023
Isolation and culture of human mature adipocytes using membrane mature adipocyte aggregate cultures (MAAC)
I Alexandersson, MJ Harms, J Boucher
JoVE (Journal of Visualized Experiments), e60485, 2020
152020
Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures
M Soták, MR Rajan, M Clark, M Harms, A Rani, JD Kraft, D Tandio, ...
Iscience 25 (7), 2022
62022
Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects
DK Bauknight, V Osinski, SSK Dasa, AT Nguyen, MA Marshall, J Hartman, ...
Plos one 14 (11), e0224917, 2019
42019
Engineering and Development of Optimal CRISPR Based Genome Modification Molecules for Safe and Effective LDL-C Lowering
C Duncan-Lewis, M Harms, M Adil, R Alcantra-Lee, F Bardai, ...
Circulation 150 (Suppl_1), A4140609-A4140609, 2024
2024
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