Brown and beige fat: development, function and therapeutic potential M Harms, P Seale Nature medicine 19 (10), 1252-1263, 2013 | 2379 | 2013 |
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice MJ Harms, J Ishibashi, W Wang, HW Lim, S Goyama, T Sato, M Kurokawa, ... Cell metabolism 19 (4), 593-604, 2014 | 402 | 2014 |
PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program MJ Harms, HW Lim, Y Ho, SN Shapira, J Ishibashi, S Rajakumari, ... Genes & development 29 (3), 298-307, 2015 | 152 | 2015 |
Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce Q Li, CE Hagberg, H Silva Cascales, S Lang, MT Hyvönen, F Salehzadeh, ... Nature medicine 27 (11), 1941-1953, 2021 | 122 | 2021 |
EBF2 promotes the recruitment of beige adipocytes in white adipose tissue RR Stine, SN Shapira, HW Lim, J Ishibashi, M Harms, KJ Won, P Seale Molecular metabolism 5 (1), 57-65, 2016 | 114 | 2016 |
The role of PDE3B phosphorylation in the inhibition of lipolysis by insulin LM DiPilato, F Ahmad, M Harms, P Seale, V Manganiello, MJ Birnbaum Molecular and cellular biology 35 (16), 2752-2760, 2015 | 111 | 2015 |
Mature human white adipocytes cultured under membranes maintain identity, function, and can transdifferentiate into brown-like adipocytes MJ Harms, Q Li, S Lee, C Zhang, B Kull, S Hallen, A Thorell, ... Cell reports 27 (1), 213-225. e5, 2019 | 110 | 2019 |
Flow cytometry of mouse and human adipocytes for the analysis of browning and cellular heterogeneity CE Hagberg, Q Li, M Kutschke, D Bhowmick, E Kiss, IG Shabalina, ... Cell reports 24 (10), 2746-2756. e5, 2018 | 93 | 2018 |
ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium N Gaudreault, N Kumar, JM Posada, KB Stephens, NS Reyes de Mochel, ... Arteriosclerosis, thrombosis, and vascular biology 32 (2), 264-272, 2012 | 88 | 2012 |
EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex SN Shapira, HW Lim, S Rajakumari, AP Sakers, J Ishibashi, MJ Harms, ... Genes & development 31 (7), 660-673, 2017 | 75 | 2017 |
PPARγ and PPARα synergize to induce robust browning of white fat in vivo T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ... Molecular metabolism 36, 100964, 2020 | 69 | 2020 |
PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing M Kissig, J Ishibashi, MJ Harms, HW Lim, RR Stine, KJ Won, P Seale The EMBO journal 36 (11), 1528-1542, 2017 | 65 | 2017 |
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity P Morigny, M Houssier, A Mairal, C Ghilain, E Mouisel, F Benhamed, ... Nature Metabolism 1 (1), 133-146, 2019 | 57 | 2019 |
The colorful versatility of adipocytes: white‐to‐brown transdifferentiation and its therapeutic potential in humans S Maurer, M Harms, J Boucher The FEBS journal 288 (12), 3628-3646, 2021 | 51 | 2021 |
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects V Osinski, DK Bauknight, SSK Dasa, MJ Harms, T Kroon, MA Marshall, ... Theranostics 10 (2), 585, 2020 | 22 | 2020 |
New approaches for targeting PCSK9: small-interfering ribonucleic acid and genome editing RF Oostveen, AV Khera, S Kathiresan, ESG Stroes, K Fitzgerald, ... Arteriosclerosis, thrombosis, and vascular biology 43 (7), 1081-1092, 2023 | 16 | 2023 |
Isolation and culture of human mature adipocytes using membrane mature adipocyte aggregate cultures (MAAC) I Alexandersson, MJ Harms, J Boucher JoVE (Journal of Visualized Experiments), e60485, 2020 | 15 | 2020 |
Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures M Soták, MR Rajan, M Clark, M Harms, A Rani, JD Kraft, D Tandio, ... Iscience 25 (7), 2022 | 6 | 2022 |
Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects DK Bauknight, V Osinski, SSK Dasa, AT Nguyen, MA Marshall, J Hartman, ... Plos one 14 (11), e0224917, 2019 | 4 | 2019 |
Engineering and Development of Optimal CRISPR Based Genome Modification Molecules for Safe and Effective LDL-C Lowering C Duncan-Lewis, M Harms, M Adil, R Alcantra-Lee, F Bardai, ... Circulation 150 (Suppl_1), A4140609-A4140609, 2024 | | 2024 |