B7-H3 in cancer–beyond immune regulation K Flem-Karlsen, Ø Fodstad, M Tan, CE Nunes-Xavier Trends in cancer 4 (6), 401-404, 2018 | 128 | 2018 |
Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors CE Nunes-Xavier, KF Karlsen, C Tekle, C Pedersen, T Øyjord, V Hongisto, ... Oncotarget 7 (6), 6891, 2016 | 80 | 2016 |
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies R Akbar, H Bashour, P Rawat, PA Robert, E Smorodina, TS Cotet, ... MAbs 14 (1), 2008790, 2022 | 72 | 2022 |
B7-H3 immune checkpoint protein in human cancer K Flem-Karlsen, Ø Fodstad, CE Nunes-Xavier Current medicinal chemistry 27 (24), 4062-4086, 2020 | 67 | 2020 |
Immunoregulatory protein B7‐H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells K Flem‐Karlsen, C Tekle, Y Andersson, K Flatmark, Ø Fodstad, ... Pigment cell & melanoma research 30 (5), 467-476, 2017 | 67 | 2017 |
Soluble AXL as a marker of disease progression and survival in melanoma K Flem-Karlsen, M Nyakas, IN Farstad, E McFadden, P Wernhoff, ... PLoS One 15 (1), e0227187, 2020 | 37 | 2020 |
p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance K Flem-Karlsen, C Tekle, T Øyjord, VA Flørenes, GM Mælandsmo, ... Scientific reports 9 (1), 5839, 2019 | 35 | 2019 |
A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma J Pozniak, D Pedri, E Landeloos, Y Van Herck, A Antoranz, ... Cell 187 (1), 166-183. e25, 2024 | 34 | 2024 |
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life A Grevys, R Frick, S Mester, K Flem-Karlsen, J Nilsen, S Foss, KMK Sand, ... Iscience 25 (2), 2022 | 31 | 2022 |
Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma K Flem-Karlsen, E McFadden, N Omar, MH Haugen, GF Øy, T Ryder, ... Molecular cancer therapeutics 19 (3), 895-905, 2020 | 26 | 2020 |
IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory G Micevic, A Daniels, K Flem-Karlsen, K Park, R Talty, M McGeary, ... Proceedings of the National Academy of Sciences 120 (30), e2304319120, 2023 | 13 | 2023 |
Heterogeneous expression and subcellular localization of pyruvate dehydrogenase complex in prostate cancer CE Nunes-Xavier, J Mingo, M Emaldi, K Flem-Karlsen, GM Mælandsmo, ... Frontiers in Oncology 12, 873516, 2022 | 13 | 2022 |
A Three-dimensional ex vivo viability assay reveals a strong correlation between response to targeted inhibitors and mutation status in melanoma lymph node metastases VA Flørenes, K Flem-Karlsen, E McFadden, IR Bergheim, V Nygaard, ... Translational Oncology 12 (7), 951-958, 2019 | 9 | 2019 |
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life. iScience 25 A Grevys, R Frick, S Mester, K Flem-Karlsen, J Nilsen, S Foss, KMK Sand, ... Europe PMC free article, 2022 | 6 | 2022 |
Oncogenic role of B7-H3 from tumour cell-derived extracellular vesicles CE Nunes-Xavier, K Flem-Karlsen, Ø Fodstad Journal of Extracellular Vesicles 7, 127-127, 2018 | 1 | 2018 |
1025 Tumor-specific CD8+ T cells epigenetically licensed by IL-7R are critical for anti-tumor immunity in melanoma G Micevic, A Daniels, K Flem-Karlsen, K Park, R Talty, M McGeary, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
1234 Immunotherapy induces clonal expansion of cytotoxic tumor-specific TILs in a model of melanoma G Micevic, A Daniels, K Flem-Karlsen, R Talty, K Park, M Bosenberg, ... Journal of Investigative Dermatology 143 (5), S212, 2023 | | 2023 |
Investigating therapeutic candidates and the use of preclinical models to predict treatment response in melanoma K Flem-Karlsen Faculty of Medicine, University of Oslo, 2020 | | 2020 |
Immunoregulatory Protein B7-H3 Promotes Growth and Decreases Tumor Cell Sensitivity to Anti-Cancer Agents C Nunes-Xavier, K Flem-Karlsen, C Tekle, Ø Fodstad Annals of Oncology 28, vii12, 2017 | | 2017 |
Suppressed B7-H3 expression reduces glycolytic capacity and sensitizes tumor cells to anti-cancer agents CE Nunes-Xavier, K Flem Karlsen, T Øyjord, M Tan, Ø Fodstad Cancer Research 76 (14_Supplement), 4133-4133, 2016 | | 2016 |