| Regulatory circuitry governing fungal development, drug resistance, and disease RS Shapiro, N Robbins, LE Cowen Microbiology and Molecular Biology Reviews 75 (2), 213-267, 2011 | 705 | 2011 |
| Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling RS Shapiro, P Uppuluri, AK Zaas, C Collins, H Senn, JR Perfect, ... Current Biology 19 (8), 621-629, 2009 | 351 | 2009 |
| High-content CRISPR screening C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ... Nature Reviews Methods Primers 2 (1), 1-23, 2022 | 318 | 2022 |
| Global gene deletion analysis exploring yeast filamentous growth O Ryan, RS Shapiro, CF Kurat, D Mayhew, A Baryshnikova, B Chin, ... Science 337 (6100), 1353-1356, 2012 | 244 | 2012 |
| New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics J Geddes‐McAlister, RS Shapiro Annals of the New York Academy of Sciences, 2018 | 149 | 2018 |
| A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans RS Shapiro, A Chavez, CBM Porter, M Hamblin, CS Kaas, JE DiCarlo, ... Nature Microbiology 3 (1), 73-82, 2018 | 147 | 2018 |
| Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing RS Shapiro, LE Cowen mBio 3 (5), 2012 | 132 | 2012 |
| Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry S Diezmann, M Michaut, RS Shapiro, GD Bader, LE Cowen PLoS Genetics 8 (3), e1002562, 2012 | 120 | 2012 |
| The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance RS Shapiro, AK Zaas, M Betancourt-Quiroz, JR Perfect, LE Cowen PLOS ONE 7 (9), e44734, 2012 | 104 | 2012 |
| A role for the bacterial GATC methylome in antibiotic stress survival NR Cohen, CA Ross, S Jain, RS Shapiro, A Gutierrez, P Belenky, H Li, ... Nature Genetics, 2016 | 101 | 2016 |
| Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise RS Shapiro, A Sellam, F Tebbji, M Whiteway, A Nantel, LE Cowen Current Biology 22 (6), 461-470, 2012 | 101 | 2012 |
| CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms RS Shapiro, A Chavez, JJ Collins Nature Reviews Microbiology 16 (6), 333-339, 2018 | 96 | 2018 |
| Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans H Senn, RS Shapiro, LE Cowen Molecular Biology of the Cell 23 (2), 268-283, 2012 | 72 | 2012 |
| Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans RS Shapiro, LE Cowen Virulence 1 (1), 45-48, 2010 | 55 | 2010 |
| Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens J Sharma, S Rosiana, I Razzaq, RS Shapiro Journal of Fungi 5 (1), 17, 2019 | 52 | 2019 |
| Antimicrobial-induced DNA damage and genomic instability in microbial pathogens RS Shapiro PLoS Pathogens 11 (3), e1004678, 2015 | 51 | 2015 |
| Metabolism‐induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells GJ Thomson, C Hernon, N Austriaco, RS Shapiro, P Belenky, RJ Bennett The EMBO journal 38 (19), e101597, 2019 | 47 | 2019 |
| A CRISPR interference platform for efficient genetic repression in Candida albicans L Wensing, J Sharma, D Uthayakumar, Y Proteau, A Chavez, RS Shapiro mSphere 4 (1), 2019 | 47* | 2019 |
| Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ... PLoS Genetics 14 (3), e1007270, 2018 | 46 | 2018 |
| Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis RS Shapiro, LE Cowen Virulence 3 (4), 400-404, 2012 | 34 | 2012 |
Leah E. CowenVice-President, Research & Innovation, & Strategic Initiatives, University of Toronto在 utoronto.ca 的电子邮件经过验证
