Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes J Yang, J Huang, M Dasgupta, N Sears, M Miyagi, B Wang, MR Chance, ... Proceedings of the National Academy of Sciences 107 (50), 21499-21504, 2010 | 364 | 2010 |
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65 T Lu, MW Jackson, B Wang, M Yang, MR Chance, M Miyagi, AV Gudkov, ... Proceedings of the National Academy of Sciences 107 (1), 46-51, 2010 | 335 | 2010 |
PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB H Wei, B Wang, M Miyagi, Y She, B Gopalan, DB Huang, G Ghosh, ... Proceedings of the National Academy of Sciences 110 (33), 13516-13521, 2013 | 281 | 2013 |
Protein arginine methylation of non-histone proteins and its role in diseases H Wei, R Mundade, K Lange, T Lu Cell cycle 13 (1), 32-41, 2014 | 210 | 2014 |
Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond R Mundade, HG Ozer, H Wei, L Prabhu, T Lu Cell Cycle 13 (18), 2847-2852, 2014 | 193 | 2014 |
Genetic pathways, prevention, and treatment of sporadic colorectal cancer R Mundade, TF Imperiale, L Prabhu, PJ Loehrer, T Lu Oncoscience 1 (6), 400, 2014 | 179 | 2014 |
Critical role of NF-κB in pancreatic cancer L Prabhu, R Mundade, M Korc, PJ Loehrer, T Lu Oncotarget 5 (22), 10969, 2014 | 171 | 2014 |
The pivotal role of NF-kB in the pathogenesis and therapeutics of Alzheimer’s disease E Sun, A Motolani, L Campos, T Lu International journal of molecular sciences 23 (16), 8972, 2022 | 150 | 2022 |
Dose-dependent cross-talk between the transforming growth factor-β and interleukin-1 signaling pathways T Lu, L Tian, Y Han, M Vogelbaum, GR Stark Proceedings of the National Academy of Sciences 104 (11), 4365-4370, 2007 | 137 | 2007 |
Aberrant constitutive activation of nuclear factor κB in glioblastoma multiforme drives invasive phenotype B Raychaudhuri, Y Han, T Lu, MA Vogelbaum Journal of neuro-oncology 85, 39-47, 2007 | 135 | 2007 |
CDK8/19 Mediator kinases potentiate induction of transcription by NFκB M Chen, J Liang, H Ji, Z Yang, S Altilia, B Hu, A Schronce, ... Proceedings of the National Academy of Sciences 114 (38), 10208-10213, 2017 | 132 | 2017 |
Secreted transforming growth factor β2 activates NF-κB, blocks apoptosis, and is essential for the survival of some tumor cells T Lu, LG Burdelya, SM Swiatkowski, AD Boiko, PH Howe, GR Stark, ... Proceedings of the National Academy of Sciences 101 (18), 7112-7117, 2004 | 132 | 2004 |
Participation of the conventional calpains in apoptosis T Lu, Y Xu, MT Mericle, RL Mellgren Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1590 (1-3), 16-26, 2002 | 119 | 2002 |
NF-κB: regulation by methylation T Lu, GR Stark Cancer research 75 (18), 3692-3695, 2015 | 113 | 2015 |
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB T Lu, MW Jackson, AD Singhi, ES Kandel, M Yang, Y Zhang, AV Gudkov, ... Proceedings of the National Academy of Sciences 106 (38), 16339-16344, 2009 | 101 | 2009 |
Secretion of cytokines and growth factors as a general cause of constitutive NFκB activation in cancer T Lu, SS Sathe, SM Swiatkowski, CV Hampole, GR Stark Oncogene 23 (12), 2138-2145, 2004 | 98 | 2004 |
Cytokine overexpression and constitutive NFκB in cancer T Lu, GR Stark Cell Cycle 3 (9), 1112-1115, 2004 | 89 | 2004 |
Lysine methylation of promoter-bound transcription factors and relevance to cancer GR Stark, Y Wang, T Lu Cell research 21 (3), 375-380, 2011 | 80 | 2011 |
Targeting microenvironment in cancer therapeutics M Martin, H Wei, T Lu Oncotarget 7 (32), 52575, 2016 | 76 | 2016 |
Role of post-translational modification of the Y box binding protein 1 in human cancers L Prabhu, AV Hartley, M Martin, F Warsame, E Sun, T Lu Genes & diseases 2 (3), 240-246, 2015 | 66 | 2015 |