4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration E Saijo, MA Metrick, S Koga, P Parchi, I Litvan, S Spina, A Boxer, ... Acta neuropathologica 139, 63-77, 2020 | 126 | 2020 |
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease A Kraus, E Saijo, MA Metrick, K Newell, CJ Sigurdson, G Zanusso, ... Acta neuropathologica 137, 585-598, 2019 | 116 | 2019 |
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases MA Metrick, NC Ferreira, E Saijo, A Kraus, K Newell, G Zanusso, ... Acta neuropathologica communications 8, 1-13, 2020 | 82 | 2020 |
Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons MA Metrick, N do Carmo Ferreira, E Saijo, AG Hughson, A Kraus, C Orrú, ... Proceedings of the National Academy of Sciences 116 (46), 23029-23039, 2019 | 78 | 2019 |
Ultrasensitive RT-QuIC seed amplification assays for disease-associated tau, α-synuclein, and prion aggregates E Saijo, BR Groveman, A Kraus, M Metrick, CD Orrù, AG Hughson, ... Protein Misfolding Diseases: Methods and Protocols, 19-37, 2019 | 69 | 2019 |
The effects of buffers and pH on the thermal stability, unfolding and substrate binding of RecA MA Metrick, JE Temple, G MacDonald Biophysical chemistry 184, 29-36, 2013 | 47 | 2013 |
Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear NC Ferreira, JM Charco, J Plagenz, CD Orru, ND Denkers, MA Metrick, ... Scientific reports 11 (1), 7702, 2021 | 37 | 2021 |
Hofmeister ion effects on the solvation and thermal stability of model proteins lysozyme and myoglobin MA Metrick II, G MacDonald Colloids and Surfaces A: Physicochemical and Engineering Aspects 469, 242-251, 2015 | 37 | 2015 |
Hofmeister ion-induced changes in water structure correlate with changes in solvation of an aggregated protein complex TP Light, KM Corbett, MA Metrick, G MacDonald Langmuir 32 (5), 1360-1369, 2016 | 25 | 2016 |
Variable-field analytical ultracentrifugation: I. Time-optimized sedimentation equilibrium J Ma, M Metrick, R Ghirlando, H Zhao, P Schuck Biophysical journal 109 (4), 827-837, 2015 | 12 | 2015 |
Computational maturation of a single-domain antibody against Aβ42 aggregation J Lin, C Figazzolo, MA Metrick, P Sormanni, M Vendruscolo Chemical Science 12 (41), 13940-13948, 2021 | 7 | 2021 |
Secondary processes dominate the quiescent, spontaneous aggregation of α-synuclein at physiological pH with sodium salts RI Horne, MA Metrick, W Man, DJ Rinauro, ZF Brotzakis, S Chia, G Meisl, ... ACS Chemical Neuroscience 14 (17), 3125-3131, 2023 | 6 | 2023 |
Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration S Koga, MA Metrick, LI Golbe, A Santambrogio, M Kim, AI Soto-Beasley, ... Acta Neuropathologica Communications 11 (1), 88, 2023 | 3 | 2023 |
A brain‐seeded fibril amplification models the aggregation process of tau in Alzheimer’s disease for drug discovery A Santambrogio, M Metrick, T Löhr, R Horne, M Vendruscolo Alzheimer's & Dementia 19, e082750, 2023 | 1 | 2023 |
Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α‑Synuclein at Physiological pH with Sodium Salts MA Metrick, W Man, DJ Rinauro, ZF Brotzakis, S Chia, RI Horne, G Meisl, ... American Chemical Society, 2023 | | 2023 |
Amyloid seeding assays for the selective amplification of tau aggregates from human brain homogenates M Metrick | | 2022 |
The aggregation kinetics of α-Synuclein at neutral pH under quiescent conditions WK Man, MA Metrick, DJ Rinauro, M Vendruscolo Biophysical Journal 121 (3), 299a-300a, 2022 | | 2022 |
Therapeutic drug targeting in Alzheimer's disease R Geiser, M Sanguanini, R Staats, D Rinauro, M Metrick, P Ciryam, ... Biophysical Journal 121 (3), 190a, 2022 | | 2022 |
RT-QuIC as an antemortem diagnostic tool to detect chronic wasting disease in deer skin NC Ferreira, JM Charco, MA Metrick, CD Orru, AG Hughson, J Castilla, ... PRION 13, 139-140, 2019 | | 2019 |
Hofmeister Ion and Cosolvent Effects on the Structure, Aggregation, and Backbone Solvation of RecA TP Light, KM Corbett, MA Metrick, G MacDonald Biophysical Journal 108 (2), 217a, 2015 | | 2015 |