Pre‐transplant antibody screening and anti‐CD154 costimulation blockade promote long‐term xenograft survival in a pig‐to‐primate kidney transplant model L Higginbotham, D Mathews, CA Breeden, M Song, AB Farris III, ... Xenotransplantation 22 (3), 221-230, 2015 | 207 | 2015 |
Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion SC Kim, DV Mathews, CP Breeden, LB Higginbotham, J Ladowski, ... American Journal of Transplantation 19 (8), 2174-2185, 2019 | 178 | 2019 |
Fc-silent anti-CD154 domain antibody effectively prevents nonhuman primate renal allograft rejection SC Kim, W Wakwe, LB Higginbotham, DV Mathews, CP Breeden, ... American Journal of Transplantation 17 (5), 1182-1192, 2017 | 92 | 2017 |
Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity QD Mac, DV Mathews, JA Kahla, CM Stoffers, OM Delmas, BA Holt, ... Nature biomedical engineering 3 (4), 281-291, 2019 | 78 | 2019 |
Increased pretransplant frequency of CD28+ CD4+ TEM predicts belatacept-resistant rejection in human renal transplant recipients M Cortes-Cerisuelo, SJ Laurie, DV Mathews, PD Winterberg, CP Larsen, ... American Journal of Transplantation 17 (9), 2350-2362, 2017 | 61 | 2017 |
Belatacept-resistant rejection is associated with CD28+ memory CD8 T cells DV Mathews, WC Wakwe, SC Kim, MC Lowe, C Breeden, ME Roberts, ... American Journal of Transplantation 17 (9), 2285-2299, 2017 | 56 | 2017 |
CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection DV Mathews, Y Dong, LB Higginbotham, SC Kim, CP Breeden, ... The Journal of clinical investigation 128 (10), 4557-4572, 2018 | 50 | 2018 |
Interruption of OX40L signaling prevents costimulation blockade–resistant allograft rejection WH Kitchens, Y Dong, DV Mathews, CP Breeden, E Strobert, ME Fuentes, ... JCI insight 2 (5), 2017 | 15 | 2017 |
Methods And Compositions For Noninvasive Detection Of Organ Transplant Rejection GA Kwong, AB Adams, Q Mac, DV Mathews US Patent App. 16/337,886, 2019 | 11 | 2019 |
CD4 depletion is necessary and sufficient for long-term pig-to-nonhuman primate renal xenotransplant survival S Kim, LB Higginbotham, DV Mathews, C Breeden, Y Dong, ... Xenotransplantation 24 (5), 2017 | 7 | 2017 |
Alloimmunity but not viral immunity promotes allograft loss in a mouse model of polyomavirus-associated allograft injury SC Kim, J Wang, Y Dong, DV Mathews, JA Albrecht, CP Breeden, ... Transplantation Direct 3 (6), e161, 2017 | 5 | 2017 |
In-vivo application of Ides (Imlifidase) in nonhuman primates results in xenoreactive desensitization: a novel anti-humoral therapy BP Lovasik, AJ Matar, DA Faber, DV Mathews, C Breeden, SC Kim, ... AMERICAN JOURNAL OF TRANSPLANTATION 20, 362-362, 2020 | 2 | 2020 |
Acute Rejection in Non-Human Primates Treated with Belatacept Is Mediated by a Unique CD8 Memory Subset. D Mathews, W Wakwe, M Lowe, C Breeden, F Leopardi, A Farris, M Song, ... AMERICAN JOURNAL OF TRANSPLANTATION 16, 205-206, 2016 | 2 | 2016 |
LONG-TERM SURVIVAL OF PIG-TO-PRIMATE RENAL XENOTRANSPLANT USING COSTIMULATION-BLOCKADE IMMUNOSUPPRESSION. L Higginbotham, D Mathews, A Stephenson, C Breeden, CP Larsen, ... Transplantation 99 (11), S72-S73, 2015 | 2 | 2015 |
CD28-directed therapy prolongs survival in a non-human primate kidney transplant model L Higginbotham, D Mathews, C Breeden, W Wakwe, C Larsen, S Nadler, ... AMERICAN JOURNAL OF TRANSPLANTATION 15, 2015 | 2 | 2015 |
CD28-selective inhibition prolongs non-human primate kidney transplant survival BP Lovasik, SC Kim, L Higginbotham, W Wakwe, DV Mathews, ... bioRxiv, 2023.05. 03.539333, 2023 | 1 | 2023 |
Noninvasive Imaging of CD122+ T Cells via Immuno-PET for Detection of Acute Cellular Rejection AJ Matar, BP Lovasik, D Vanover, L Rotolo, Y Dong, DA Faber, ... AMERICAN JOURNAL OF TRANSPLANTATION 20, 304-304, 2020 | 1 | 2020 |
Sensing T Cell Killing Activity with Granzyme B Activity Probes. Q Mac, D Mathews, J Kahla, C Stoffers, O Delmas, B Holt, A Adams, ... AMERICAN JOURNAL OF TRANSPLANTATION 18, 492-493, 2018 | 1 | 2018 |
CD28 directed immunotherapy is more potent than belatacept in a pig-to-nonhuman primate renal xenotransplant model S Kim, L Higginbotham, DV Mathews, C Breeden, A Stephenson, ... Xenotransplantation 24 (5), 2017 | 1 | 2017 |
Costimulation Independent Acute Rejection Requires CD127 Signaling D Mathews, Y Dong, S Kim, C Breeden, A Adams AMERICAN JOURNAL OF TRANSPLANTATION 17, 403-404, 2017 | 1 | 2017 |