HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ... Nature communications 8 (1), 861, 2017 | 361 | 2017 |
Energy metabolism in ALS: an underappreciated opportunity? T Vandoorne, K De Bock, L Van Den Bosch Acta neuropathologica 135, 489-509, 2018 | 218 | 2018 |
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis H Wang, W Guo, J Mitra, PM Hegde, T Vandoorne, BJ Eckelmann, S Mitra, ... Nature Communications 9 (1), 3683, 2018 | 172 | 2018 |
Intake of a ketone ester drink during recovery from exercise promotes mTORC1 signaling but not glycogen resynthesis in human muscle T Vandoorne, S De Smet, M Ramaekers, R Van Thienen, K De Bock, ... Frontiers in physiology 8, 310, 2017 | 111 | 2017 |
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility L Fumagalli, FL Young, S Boeynaems, M De Decker, AR Mehta, ... Science advances 7 (15), eabg3013, 2021 | 75 | 2021 |
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations R Fazal, S Boeynaems, A Swijsen, M De Decker, L Fumagalli, M Moisse, ... The EMBO journal 40 (7), e106177, 2021 | 73 | 2021 |
Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition KS Dittlau, EN Krasnow, L Fumagalli, T Vandoorne, P Baatsen, ... Stem Cell Reports 16 (9), 2213-2227, 2021 | 60 | 2021 |
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism T Vandoorne, K Veys, W Guo, A Sicart, K Vints, A Swijsen, M Moisse, ... Nature communications 10 (1), 4147, 2019 | 54 | 2019 |
The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications W Guo, T Vandoorne, J Steyaert, KA Staats, L Van Den Bosch Brain 143 (6), 1651-1673, 2020 | 44 | 2020 |
Physical activity counteracts tumor cell growth in colon carcinoma C26-injected muscles: an interim report C Hiroux, T Vandoorne, K Koppo, S De Smet, P Hespel, E Berardi European Journal of Translational Myology 26 (2), 2016 | 28 | 2016 |
Generation of human motor units with functional neuromuscular junctions in microfluidic devices KS Dittlau, EN Krasnow, L Fumagalli, T Vandoorne, P Baatsen, ... JoVE (Journal of Visualized Experiments), e62959, 2021 | 15 | 2021 |
Existing and emerging metabolomic tools for ALS research C Germeys, T Vandoorne, V Bercier, L Van Den Bosch Genes 10 (12), 1011, 2019 | 12 | 2019 |
Intake of a ketone ester drink during recovery from exercise promotes mTORC1 signalling but not glycogen resynthesis in human muscle. Front Physiol. 2017; 8: 310 T Vandoorne, S De Smet, M Ramaekers | 2 | |
ALS reactive astrocytes impair neuromuscular junctions in microfluidic devices KS Dittlau, E Krasnow, L Fumagalli, T Vandoorne, L Terrie, P Baatsen, ... Glia 69 (Suppl. 1), E188-E189, 2021 | | 2021 |
ROLE AND THERAPEUTIC POTENTIAL OF ENERGY METABOLISM IN ALS T VANDOORNE KU Leuven, 2019 | | 2019 |
Motor neurons derived from ALS patients with FUS mutations mimic disease-related phenotypes in vitro W Guo, L Fumagalli, S PATEL, D Bohl, P Vanden Berghe, W Robberecht, ... Annual Meeting of the Society for Neuroscience (SfN), Date: 2016/11/12-2016 …, 2016 | | 2016 |