| RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2 M Chen, L Wei, CT Law, FHC Tsang, J Shen, CLH Cheng, LH Tsang, ... Hepatology 67 (6), 2254-2270, 2018 | 1088 | 2018 |
| Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma DKC Chiu, APW Tse, IMJ Xu, J Di Cui, RKH Lai, LL Li, HY Koh, ... Nature communications 8 (1), 517, 2017 | 365 | 2017 |
| Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma CCL Wong, APW Tse, YP Huang, YT Zhu, DKC Chiu, RKH Lai, SLK Au, ... Hepatology 60 (5), 1645-1658, 2014 | 276 | 2014 |
| Transketolase counteracts oxidative stress to drive cancer development IMJ Xu, RKH Lai, SH Lin, APW Tse, DKC Chiu, HY Koh, CT Law, ... Proceedings of the National Academy of Sciences 113 (6), E725-E734, 2016 | 228 | 2016 |
| Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26 DKC Chiu, IMJ Xu, RKH Lai, APW Tse, LL Wei, HY Koh, LL Li, D Lee, ... Hepatology 64 (3), 797-813, 2016 | 208 | 2016 |
| Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3 L Wei, DKC Chiu, FHC Tsang, CT Law, CLH Cheng, SLK Au, JMF Lee, ... Journal of hepatology 67 (4), 758-769, 2017 | 141 | 2017 |
| Induction of oxidative stress through inhibition of thioredoxin reductase 1 is an effective therapeutic approach for hepatocellular carcinoma D Lee, IMJ Xu, DKC Chiu, J Leibold, APW Tse, MHR Bao, VWH Yuen, ... Hepatology 69 (4), 1768-1786, 2019 | 131 | 2019 |
| Hepatocellular carcinoma cells up-regulate PVRL1, stabilizing PVR and inhibiting the cytotoxic T-cell response via TIGIT to mediate tumor resistance to PD1 inhibitors in mice DKC Chiu, VWH Yuen, JWS Cheu, LL Wei, V Ting, M Fehlings, ... Gastroenterology 159 (2), 609-623, 2020 | 127 | 2020 |
| Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma D Lee, IMJ Xu, DKC Chiu, RKH Lai, APW Tse, LL Li, CT Law, FHC Tsang, ... The Journal of clinical investigation 127 (5), 1856-1872, 2017 | 125 | 2017 |
| Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway D Kung-Chun Chiu, A Pui-Wah Tse, CT Law, I Ming-Jing Xu, D Lee, ... Cell death & disease 10 (12), 934, 2019 | 122 | 2019 |
| Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis CCL Wong, SLK Au, APW Tse, IMJ Xu, RKH Lai, DKC Chiu, LL Wei, ... PloS one 9 (12), e115036, 2014 | 82 | 2014 |
| NDUFA4L2 fine-tunes oxidative stress in hepatocellular carcinoma RKH Lai, IMJ Xu, DKC Chiu, APW Tse, LL Wei, CT Law, D Lee, CM Wong, ... Clinical Cancer Research 22 (12), 3105-3117, 2016 | 73 | 2016 |
| Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer MS Zhang, JD Cui, D Lee, VWH Yuen, DKC Chiu, CC Goh, JWS Cheu, ... Nature Communications 13 (1), 954, 2022 | 60 | 2022 |
| Neutrophil-activating therapy for the treatment of cancer IL Linde, TR Prestwood, J Qiu, G Pilarowski, MH Linde, X Zhang, L Shen, ... Cancer Cell 41 (2), 356-372. e10, 2023 | 50 | 2023 |
| Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer MHR Bao, C Yang, APW Tse, L Wei, D Lee, MS Zhang, CC Goh, ... Cell Reports 34 (4), 2021 | 41 | 2021 |
| Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer APW Tse, KMF Sze, QTK Shea, EYT Chiu, FHC Tsang, DKC Chiu, ... Oncogenesis 7 (5), 44, 2018 | 36 | 2018 |
| CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma CYK Chan, DKC Chiu, VWH Yuen, CT Law, BPY Wong, KL Thu, ... Proceedings of the National Academy of Sciences 119 (32), e2119514119, 2022 | 27 | 2022 |
| Adipose‐derived stem cells and cancer cells fuse to generate cancer stem cell‐like cells with increased tumorigenicity YW Chan, C So, KL Yau, KC Chiu, X Wang, FL Chan, SY Tsang Journal of Cellular Physiology 235 (10), 6794-6807, 2020 | 24 | 2020 |
| Polo‐like kinase 4 inhibitor CFI‐400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity CYK Chan, VWH Yuen, DKC Chiu, CC Goh, KL Thu, DW Cescon, ... Hepatology 77 (3), 729-744, 2023 | 22 | 2023 |
| The Amot/integrin protein complex transmits mechanical forces required for vascular expansion Y Zhang, Y Zhang, S Kameishi, G Barutello, Y Zheng, NP Tobin, J Nicosia, ... Cell Reports 36 (8), 2021 | 22 | 2021 |
