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Iris Jansen
Iris Jansen
在 vu.nl 的电子邮件经过验证
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
AE Renton, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ...
Neuron 72 (2), 257-268, 2011
47982011
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
IE Jansen, JE Savage, K Watanabe, J Bryois, DM Williams, S Steinberg, ...
Nature genetics 51 (3), 404-413, 2019
19792019
New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
10872022
The genetic architecture of the human cerebral cortex
KL Grasby, N Jahanshad, JN Painter, L Colodro-Conde, J Bralten, ...
Science 367 (6484), eaay6690, 2020
6322020
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
DP Wightman, IE Jansen, JE Savage, AA Shadrin, S Bahrami, D Holland, ...
Nature genetics 53 (9), 1276-1282, 2021
5842021
Loss of VPS13C function in autosomal-recessive parkinsonism causes mitochondrial dysfunction and increases PINK1/Parkin-dependent mitophagy
S Lesage, V Drouet, E Majounie, V Deramecourt, M Jacoupy, A Nicolas, ...
The American Journal of Human Genetics 98 (3), 500-513, 2016
4172016
Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease
LA Robak, IE Jansen, J Van Rooij, AG Uitterlinden, R Kraaij, J Jankovic, ...
Brain 140 (12), 3191-3203, 2017
3982017
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
3842022
Genome-wide pleiotropy between Parkinson disease and autoimmune diseases
A Witoelar, IE Jansen, Y Wang, RS Desikan, JR Gibbs, C Blauwendraat, ...
JAMA neurology 74 (7), 780-792, 2017
2822017
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ...
Nature communications 10 (1), 3669, 2019
2752019
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's
G Liu, B Boot, JJ Locascio, IE Jansen, S Winder‐Rhodes, S Eberly, ...
Annals of neurology 80 (5), 674-685, 2016
2602016
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ...
Nature communications 12 (1), 3417, 2021
2002021
Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts
G Liu, JJ Locascio, JC Corvol, B Boot, Z Liao, K Page, D Franco, K Burke, ...
The Lancet Neurology 16 (8), 620-629, 2017
1562017
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease
IJ Broce, CH Tan, CC Fan, I Jansen, JE Savage, A Witoelar, N Wen, ...
Acta neuropathologica 137 (2), 209-226, 2019
1422019
Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics
BM Tijms, J Gobom, L Reus, I Jansen, S Hong, V Dobricic, F Kilpert, ...
Brain 143 (12), 3776-3792, 2020
1202020
Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing
IE Jansen, H Ye, S Heetveld, MC Lechler, H Michels, RI Seinstra, ...
Genome biology 18, 1-26, 2017
1202017
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the …
SJ Van Der Lee, OJ Conway, I Jansen, MM Carrasquillo, L Kleineidam, ...
Acta neuropathologica 138, 237-250, 2019
1142019
NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases
MA Nalls, J Bras, DG Hernandez, MF Keller, E Majounie, AE Renton, ...
Neurobiology of aging 36 (3), 1605. e7-1605. e12, 2015
1142015
Associations of autozygosity with a broad range of human phenotypes
DW Clark, Y Okada, KHS Moore, D Mason, N Pirastu, I Gandin, ...
Nature communications 10 (1), 4957, 2019
1022019
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ...
Nature genetics 54 (12), 1786-1794, 2022
882022
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