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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk IE Jansen, JE Savage, K Watanabe, J Bryois, DM Williams, S Steinberg, ... Nature genetics 51 (3), 404-413, 2019 | 1979 | 2019 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1087 | 2022 |
The genetic architecture of the human cerebral cortex KL Grasby, N Jahanshad, JN Painter, L Colodro-Conde, J Bralten, ... Science 367 (6484), eaay6690, 2020 | 632 | 2020 |
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease DP Wightman, IE Jansen, JE Savage, AA Shadrin, S Bahrami, D Holland, ... Nature genetics 53 (9), 1276-1282, 2021 | 584 | 2021 |
Loss of VPS13C function in autosomal-recessive parkinsonism causes mitochondrial dysfunction and increases PINK1/Parkin-dependent mitophagy S Lesage, V Drouet, E Majounie, V Deramecourt, M Jacoupy, A Nicolas, ... The American Journal of Human Genetics 98 (3), 500-513, 2016 | 417 | 2016 |
Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease LA Robak, IE Jansen, J Van Rooij, AG Uitterlinden, R Kraaij, J Jankovic, ... Brain 140 (12), 3191-3203, 2017 | 398 | 2017 |
A saturated map of common genetic variants associated with human height L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ... Nature 610 (7933), 704-712, 2022 | 384 | 2022 |
Genome-wide pleiotropy between Parkinson disease and autoimmune diseases A Witoelar, IE Jansen, Y Wang, RS Desikan, JR Gibbs, C Blauwendraat, ... JAMA neurology 74 (7), 780-792, 2017 | 282 | 2017 |
A meta-analysis of genome-wide association studies identifies multiple longevity genes J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ... Nature communications 10 (1), 3669, 2019 | 275 | 2019 |
Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's G Liu, B Boot, JJ Locascio, IE Jansen, S Winder‐Rhodes, S Eberly, ... Annals of neurology 80 (5), 674-685, 2016 | 260 | 2016 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 200 | 2021 |
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease IJ Broce, CH Tan, CC Fan, I Jansen, JE Savage, A Witoelar, N Wen, ... Acta neuropathologica 137 (2), 209-226, 2019 | 142 | 2019 |
Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics BM Tijms, J Gobom, L Reus, I Jansen, S Hong, V Dobricic, F Kilpert, ... Brain 143 (12), 3776-3792, 2020 | 120 | 2020 |
Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing IE Jansen, H Ye, S Heetveld, MC Lechler, H Michels, RI Seinstra, ... Genome biology 18, 1-26, 2017 | 120 | 2017 |
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the … SJ Van Der Lee, OJ Conway, I Jansen, MM Carrasquillo, L Kleineidam, ... Acta neuropathologica 138, 237-250, 2019 | 114 | 2019 |
NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases MA Nalls, J Bras, DG Hernandez, MF Keller, E Majounie, AE Renton, ... Neurobiology of aging 36 (3), 1605. e7-1605. e12, 2015 | 114 | 2015 |
Associations of autozygosity with a broad range of human phenotypes DW Clark, Y Okada, KHS Moore, D Mason, N Pirastu, I Gandin, ... Nature communications 10 (1), 4957, 2019 | 102 | 2019 |
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ... Nature genetics 54 (12), 1786-1794, 2022 | 88 | 2022 |