Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III DB Simon, RS Bindra, TA Mansfield, C Nelson-Williams, E Mendonca, ... Nature genetics 17 (2), 171-178, 1997 | 1020 | 1997 |
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ... Neuro-oncology 22 (8), 1073-1113, 2020 | 745 | 2020 |
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity PL Sulkowski, CD Corso, ND Robinson, SE Scanlon, KR Purshouse, ... Science translational medicine 9 (375), eaal2463, 2017 | 523 | 2017 |
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells RS Bindra, PJ Schaffer, A Meng, J Woo, K Måseide, ME Roth, P Lizardi, ... Molecular and cellular biology 24 (19), 8504-8518, 2004 | 415 | 2004 |
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs RS Bindra, SL Gibson, A Meng, U Westermark, M Jasin, AJ Pierce, ... Cancer research 65 (24), 11597-11604, 2005 | 384 | 2005 |
Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging K Chang, HX Bai, H Zhou, C Su, WL Bi, E Agbodza, VK Kavouridis, ... Clinical Cancer Research 24 (5), 1073-1081, 2018 | 374 | 2018 |
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ... Cancer research 68 (2), 605-614, 2008 | 355 | 2008 |
Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells VT Mihaylova, RS Bindra, J Yuan, D Campisi, L Narayanan, R Jensen, ... Molecular and cellular biology 23 (9), 3265-3273, 2003 | 333 | 2003 |
Inhibition of poly (ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130 DC Hegan, Y Lu, GC Stachelek, ME Crosby, RS Bindra, PM Glazer Proceedings of the National Academy of Sciences 107 (5), 2201-2206, 2010 | 250 | 2010 |
Regulation of DNA repair in hypoxic cancer cells RS Bindra, ME Crosby, PM Glazer Cancer and Metastasis Reviews 26, 249-260, 2007 | 244 | 2007 |
Oncometabolites suppress DNA repair by disrupting local chromatin signalling PL Sulkowski, S Oeck, J Dow, NG Economos, L Mirfakhraie, Y Liu, ... Nature 582 (7813), 586-591, 2020 | 236 | 2020 |
Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells AX Meng, F Jalali, A Cuddihy, N Chan, RS Bindra, PM Glazer, RG Bristow Radiotherapy and Oncology 76 (2), 168-176, 2005 | 218 | 2005 |
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis RS Bindra, PM Glazer Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 569 (1 …, 2005 | 206 | 2005 |
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair PL Sulkowski, RK Sundaram, S Oeck, CD Corso, Y Liu, S Noorbakhsh, ... Nature Genetics 50 (8), 1086-1092, 2018 | 187 | 2018 |
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia RS Bindra, PM Glazer Oncogene 26 (14), 2048-2057, 2007 | 177 | 2007 |
Hypoxia-induced genetic instability—a calculated mechanism underlying tumor progression LE Huang, RS Bindra, PM Glazer, AL Harris Journal of Molecular Medicine 85, 139-148, 2007 | 176 | 2007 |
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ... Cell reports 20 (8), 1921-1935, 2017 | 174 | 2017 |
VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells RS Bindra, JR Vasselli, R Stearman, WM Linehan, RD Klausner Cancer research 62 (11), 3014-3019, 2002 | 159 | 2002 |
Pediatric high-grade glioma: current molecular landscape and therapeutic approaches S Braunstein, D Raleigh, R Bindra, S Mueller, D Haas-Kogan Journal of neuro-oncology 134, 541-549, 2017 | 149 | 2017 |
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network RS Bindra, PM Glazer Cancer letters 252 (1), 93-103, 2007 | 117 | 2007 |