Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme K Ovaska, M Laakso, S Haapa-Paananen, R Louhimo, P Chen, ... Genome medicine 2, 1-12, 2010 | 229 | 2010 |
Genome-wide association study of diabetic kidney disease highlights biology involved in glomerular basement membrane collagen RM Salem, JN Todd, N Sandholm, JB Cole, WM Chen, D Andrews, ... Journal of the American Society of Nephrology 30 (10), 2000-2016, 2019 | 161 | 2019 |
A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes NR Van Zuydam, E Ahlqvist, N Sandholm, H Deshmukh, NW Rayner, ... Diabetes 67 (7), 1414-1427, 2018 | 161 | 2018 |
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression B Rafn, CF Nielsen, SH Andersen, P Szyniarowski, E Corcelle-Termeau, ... Molecular cell 45 (6), 764-776, 2012 | 132 | 2012 |
The genetic landscape of renal complications in type 1 diabetes N Sandholm, N Van Zuydam, E Ahlqvist, T Juliusdottir, HA Deshmukh, ... Journal of the American Society of Nephrology 28 (2), 557-574, 2017 | 129 | 2017 |
Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation DP Mathiasen, C Egebjerg, SH Andersen, B Rafn, P Puustinen, A Khanna, ... Oncogene 31 (3), 390-401, 2012 | 60 | 2012 |
Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase M Backlund, K Paukku, L Daviet, RA De Boer, E Valo, S Hautaniemi, ... Nucleic acids research 37 (7), 2346-2358, 2009 | 54 | 2009 |
Biomarker panels associated with progression of renal disease in type 1 diabetes M Colombo, E Valo, SJ McGurnaghan, N Sandholm, LAK Blackbourn, ... Diabetologia 62, 1616-1627, 2019 | 41 | 2019 |
Variations in risk of end-stage renal disease and risk of mortality in an international study of patients with type 1 diabetes and advanced nephropathy J Skupien, AM Smiles, E Valo, TS Ahluwalia, B Gyorgy, N Sandholm, ... Diabetes Care 42 (1), 93-101, 2019 | 41 | 2019 |
Urinary metabolite profiling and risk of progression of diabetic nephropathy in 2670 individuals with type 1 diabetes S Mutter, E Valo, V Aittomäki, K Nybo, L Raivonen, LM Thorn, C Forsblom, ... Diabetologia 65, 140-149, 2022 | 34 | 2022 |
Rituximab regulates signaling pathways and alters gene expression associated with cell death and survival in diffuse large B-cell lymphoma S Koivula, E Valo, A Raunio, S Hautaniemi, S Leppä Oncology reports 25 (4), 1183-1190, 2011 | 23 | 2011 |
Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease N Sandholm, JB Cole, V Nair, X Sheng, H Liu, E Ahlqvist, N Van Zuydam, ... Diabetologia 65 (9), 1495-1509, 2022 | 19 | 2022 |
Urinary proteomics identifies cathepsin D as a biomarker of rapid eGFR decline in type 1 diabetes CP Limonte, E Valo, V Drel, L Natarajan, M Darshi, C Forsblom, ... Diabetes Care 45 (6), 1416-1427, 2022 | 17 | 2022 |
Effect of serum sample storage temperature on metabolomic and proteomic biomarkers E Valo, M Colombo, N Sandholm, SJ McGurnaghan, LAK Blackbourn, ... Scientific Reports 12 (1), 4571, 2022 | 17 | 2022 |
Genome-wide association study on coronary artery disease in type 1 diabetes suggests beta-defensin 127 as a risk locus AAV Antikainen, N Sandholm, DA Trégouët, R Charmet, AJ McKnight, ... Cardiovascular Research 117 (2), 600-612, 2021 | 17 | 2021 |
Genetic determinants of glycated hemoglobin in type 1 diabetes A Syreeni, N Sandholm, J Cao, I Toppila, DM Maahs, MJ Rewers, ... Diabetes 68 (4), 858-867, 2019 | 16 | 2019 |
Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes N Sandholm, JK Haukka, I Toppila, E Valo, V Harjutsalo, C Forsblom, ... Scientific Reports 8 (1), 12408, 2018 | 16 | 2018 |
Whole-genome sequencing of Finnish type 1 diabetic siblings discordant for kidney disease reveals DNA variants associated with diabetic nephropathy J Guo, OJL Rackham, N Sandholm, B He, AM Österholm, E Valo, ... Journal of the American Society of Nephrology 31 (2), 309-323, 2020 | 13 | 2020 |
A targeted multiomics approach to identify biomarkers associated with rapid eGFR decline in type 1 diabetes CP Limonte, E Valo, D Montemayor, F Afshinnia, TS Ahluwalia, ... American journal of nephrology 51 (10), 839-848, 2020 | 12 | 2020 |
Novel linkage peaks discovered for diabetic nephropathy in individuals with type 1 diabetes J Haukka, N Sandholm, E Valo, C Forsblom, V Harjutsalo, JB Cole, ... Diabetes 70 (4), 986-995, 2021 | 11 | 2021 |