Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization K Spilsbury, KL Garrett, WY Shen, IJ Constable, PE Rakoczy The American journal of pathology 157 (1), 135-144, 2000 | 513 | 2000 |
Differentiation of marrow stromal cells into photoreceptors in the rat eye A Kicic, WY Shen, AS Wilson, IJ Constable, T Robertson, PE Rakoczy Journal of Neuroscience 23 (21), 7742-7749, 2003 | 388 | 2003 |
Conditional Müller cell ablation causes independent neuronal and vascular pathologies in a novel transgenic model W Shen, M Fruttiger, L Zhu, SH Chung, NL Barnett, JK Kirk, SR Lee, ... Journal of Neuroscience 32 (45), 15715-15727, 2012 | 249 | 2012 |
Expression of cell adhesion molecules and vascular endothelial growth factor in experimental choroidal neovascularisation in the rat WY Shen, MJT Yu, CJ Barry, IJ Constable, PE Rakoczy British Journal of Ophthalmology 82 (9), 1063-1071, 1998 | 190 | 1998 |
Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys CM Lai, WY Shen, M Brankov, YKY Lai, NL Barnett, SY Lee, IYS Yeo, ... Molecular Therapy 12 (4), 659-668, 2005 | 172 | 2005 |
Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy YKY Lai, WY Shen, M Brankov, CM Lai, IJ Constable, PE Rakoczy Gene therapy 9 (12), 804-813, 2002 | 164 | 2002 |
The role of glia in retinal vascular disease NJ Coorey, W Shen, SH Chung, L Zhu, MC Gillies Clinical and Experimental Optometry 95 (3), 266-281, 2012 | 155 | 2012 |
Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization CM Lai, M Brankov, T Zaknich, YKY Lai, WY Shen, IJ Constable, I Kovesdi, ... Human gene therapy 12 (10), 1299-1310, 2001 | 146 | 2001 |
Argon laser photocoagulation–induced modification of gene expression in the retina AS Wilson, BG Hobbs, WY Shen, TP Speed, U Schmidt, CG Begley, ... Investigative ophthalmology & visual science 44 (4), 1426-1434, 2003 | 123 | 2003 |
Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium W Shen, S Li, SH Chung, L Zhu, J Stayt, T Su, PO Couraud, IA Romero, ... European journal of cell biology 90 (4), 323-332, 2011 | 110 | 2011 |
Optogenetic approaches to vision restoration MP Simunovic, W Shen, JY Lin, DA Protti, L Lisowski, MC Gillies Experimental eye research 178, 15-26, 2019 | 102 | 2019 |
Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization A Kvanta, WY Shen, S Sarman, S Seregard, B Steen, E Rakoczy Current eye research 21 (3), 684-690, 2000 | 100 | 2000 |
Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene KP Burdon, RD Fogarty, W Shen, S Abhary, G Kaidonis, B Appukuttan, ... Diabetologia 58, 2288-2297, 2015 | 99 | 2015 |
Chloroquine and hydroxychloroquine are novel inhibitors of human organic anion transporting polypeptide 1A2 C Xu, L Zhu, T Chan, X Lu, W Shen, MC Madigan, MC Gillies, F Zhou Journal of pharmaceutical sciences 105 (2), 884-890, 2016 | 92 | 2016 |
Evaluation of adeno-associated virus-mediated gene transfer into the rat retina by clinical fluorescence photography F Rolling, WY Shen, H Tabarias, I Constable, Y Kanagasingam, CJ Barry, ... Human gene therapy 10 (4), 641-648, 1999 | 89 | 1999 |
Retinal vascular changes after glial disruption in rats W Shen, S Li, SH Chung, MC Gillies Journal of neuroscience research 88 (7), 1485-1499, 2010 | 75 | 2010 |
Generation of transgenic mice with mild and severe retinal neovascularisation CM Lai, SA Dunlop, LA May, M Gorbatov, M Brankov, WY Shen, N Binz, ... British journal of ophthalmology 89 (7), 911-916, 2005 | 72 | 2005 |
In vivo use of oligonucleotides to inhibit choroidal neovascularisation in the eye KL Garrett, WY Shen, PE Rakoczy The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2001 | 68 | 2001 |
Targeting the Notch and TGF-β signaling pathways to prevent retinal fibrosis in vitro and in vivo J Fan, W Shen, SR Lee, AE Mathai, R Zhang, G Xu, MC Gillies Theranostics 10 (18), 7956, 2020 | 61 | 2020 |
Long-term global retinal microvascular changes in a transgenic vascular endothelial growth factor mouse model WY Shen, CM Lai, CE Graham, N Binz, YKY Lai, J Eade, D Guidolin, ... Diabetologia 49, 1690-1701, 2006 | 61 | 2006 |