Fatty acid-binding protein 5 facilitates the blood–brain barrier transport of docosahexaenoic acid Y Pan, MJ Scanlon, Y Owada, Y Yamamoto, CJH Porter, JA Nicolazzo Molecular pharmaceutics 12 (12), 4375-4385, 2015 | 120 | 2015 |
Impact of aging, Alzheimer's disease and Parkinson's disease on the blood-brain barrier transport of therapeutics Y Pan, JA Nicolazzo Advanced drug delivery reviews 135, 62-74, 2018 | 100 | 2018 |
Fatty acid-binding protein 5 at the blood–brain barrier regulates endogenous brain docosahexaenoic acid levels and cognitive function Y Pan, JL Short, KHC Choy, AX Zeng, PJ Marriott, Y Owada, MJ Scanlon, ... Journal of Neuroscience 36 (46), 11755-11767, 2016 | 76 | 2016 |
The impact of docosahexaenoic acid on Alzheimer’s disease: is there a role of the blood-brain barrier? Y Pan, H Khalil, J A Nicolazzo Current clinical pharmacology 10 (3), 222-241, 2015 | 51 | 2015 |
Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid Y Pan, JL Short, SA Newman, KHC Choy, D Tiwari, C Yap, D Senyschyn, ... Brain, Behavior, and Immunity 70, 36-47, 2018 | 45 | 2018 |
Altered expression of small intestinal drug transporters and hepatic metabolic enzymes in a mouse model of familial Alzheimer’s disease Y Pan, K Omori, I Ali, M Tachikawa, T Terasaki, KLR Brouwer, ... Molecular pharmaceutics 15 (9), 4073-4083, 2018 | 26 | 2018 |
Fatty acid–binding protein 5 mediates the uptake of fatty acids, but not drugs, into human brain endothelial cells GS Lee, Y Pan, MJ Scanlon, CJH Porter, JA Nicolazzo Journal of pharmaceutical sciences 107 (4), 1185-1193, 2018 | 25 | 2018 |
Altered blood–brain barrier and blood–spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety Y Pan, JA Nicolazzo British Journal of Pharmacology 179 (11), 2577-2588, 2022 | 22 | 2022 |
Reduced blood‐brain barrier expression of fatty acid‐binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega‐3 fatty … Y Pan, KHC Choy, PJ Marriott, SY Chai, MJ Scanlon, CJH Porter, JL Short, ... Journal of neurochemistry 144 (1), 81-92, 2018 | 20 | 2018 |
Dietary docosahexaenoic acid supplementation enhances expression of fatty acid‐binding protein 5 at the blood–brain barrier and brain docosahexaenoic acid levels Y Pan, ER Morris, MJ Scanlon, PJ Marriott, CJH Porter, JA Nicolazzo Journal of Neurochemistry 146 (2), 186-197, 2018 | 19 | 2018 |
Pioglitazone Increases Blood–Brain Barrier Expression of Fatty Acid-Binding Protein 5 and Docosahexaenoic Acid Trafficking into the Brain YL Low, L Jin, ER Morris, Y Pan, JA Nicolazzo Molecular Pharmaceutics 17 (3), 873-884, 2020 | 18 | 2020 |
Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake PG Ojeda, ST Henriques, Y Pan, JA Nicolazzo, DJ Craik, CK Wang Peptide Science 108 (5), e23025, 2017 | 18 | 2017 |
Endosomal escape cell-penetrating peptides significantly enhance pharmacological effectiveness and CNS activity of systemically administered antisense oligonucleotides M Dastpeyman, R Sharifi, A Amin, JA Karas, B Cuic, Y Pan, JA Nicolazzo, ... International journal of pharmaceutics 599, 120398, 2021 | 16 | 2021 |
Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of Wnt/β-catenin signaling BA Umaru, Y Kagawa, SK Shil, N Arakawa, Y Pan, H Miyazaki, ... Pharmaceutical Research 38, 479-490, 2021 | 16 | 2021 |
Increased expression of renal drug transporters in a mouse model of familial Alzheimer's disease Y Pan, K Omori, I Ali, M Tachikawa, T Terasaki, KLR Brouwer, ... Journal of pharmaceutical sciences 108 (7), 2484-2489, 2019 | 15 | 2019 |
Development and validation of an in-cell western for quantifying P-glycoprotein expression in human brain microvascular endothelial (hCMEC/D3) cells MP McInerney, Y Pan, JL Short, JA Nicolazzo Journal of pharmaceutical sciences 106 (9), 2614-2624, 2017 | 15 | 2017 |
Blockade of microglial Kv1. 3 potassium channels by the peptide HsTX1 [R14A] attenuates lipopolysaccharide-mediated neuroinflammation JA Nicolazzo, Y Pan, I Di Stefano, KHC Choy, SB Reddiar, YL Low, ... Journal of Pharmaceutical Sciences 111 (3), 638-647, 2022 | 13 | 2022 |
Assessing the impact of lithium chloride on the expression of P-glycoprotein at the blood-brain barrier SA Newman, Y Pan, JL Short, JA Nicolazzo Journal of pharmaceutical sciences 106 (9), 2625-2631, 2017 | 12 | 2017 |
Intestinal permeability and oral absorption of selected drugs are reduced in a mouse model of familial Alzheimer’s disease L Jin, Y Pan, NLL Tran, LN Polychronopoulos, A Warrier, KLR Brouwer, ... Molecular pharmaceutics 17 (5), 1527-1537, 2020 | 11 | 2020 |
Exploiting the buccal mucosa as an alternative route for the delivery of donepezil hydrochloride T Caon, Y Pan, CMO Simões, JA Nicolazzo Journal of pharmaceutical sciences 103 (6), 1643-1651, 2014 | 10 | 2014 |