Pan-cancer alterations of the MYC oncogene and its proximal network across the cancer genome atlas FX Schaub, V Dhankani, AC Berger, M Trivedi, AB Richardson, R Shaw, ... Cell systems 6 (3), 282-300. e2, 2018 | 377 | 2018 |
Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms FX Schaub, R Looser, S Li, H Hao-Shen, T Lehmann, A Tichelli, ... Blood, The Journal of the American Society of Hematology 115 (10), 2003-2007, 2010 | 225 | 2010 |
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ... Cell systems 7 (4), 422-437. e7, 2018 | 150 | 2018 |
JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis AH Schmitt-Graeff, SS Teo, M Olschewski, F Schaub, S Haxelmans, A Kirn, ... Haematologica 93 (1), 34-40, 2008 | 146 | 2008 |
Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis FX Schaub, MS Reza, CA Flaveny, W Li, AM Musicant, S Hoxha, M Guo, ... Cancer research 75 (23), 5023-5033, 2015 | 126 | 2015 |
Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state RJ Rounbehler, M Fallahi, C Yang, MA Steeves, W Li, JR Doherty, ... Cell 150 (3), 563-574, 2012 | 117 | 2012 |
Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth H Ghalei, FX Schaub, JR Doherty, Y Noguchi, WR Roush, JL Cleveland, ... The Journal of cell biology 208 (6), 745, 2015 | 98 | 2015 |
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma A Hoellein, M Fallahi, S Schoeffmann, S Steidle, FX Schaub, M Rudelius, ... Blood, The Journal of the American Society of Hematology 124 (13), 2081-2090, 2014 | 96 | 2014 |
Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F FX Schaub, R Jäger, R Looser, H Hao-Shen, S Hermouet, F Girodon, ... Blood, The Journal of the American Society of Hematology 113 (9), 2022-2027, 2009 | 83 | 2009 |
CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB–MYC involvement AL Amelio, M Fallahi, FX Schaub, M Zhang, MB Lawani, AS Alperstein, ... Proceedings of the National Academy of Sciences 111 (32), E3260-E3268, 2014 | 35 | 2014 |
BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer GYL Lui, R Shaw, FX Schaub, IN Stork, KE Gurley, C Bridgwater, RL Diaz, ... EBioMedicine 60, 2020 | 33 | 2020 |
TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia S Yun, ND Vincelette, X Yu, GW Watson, MR Fernandez, C Yang, ... Blood cancer discovery 2 (2), 162-185, 2021 | 28 | 2021 |
Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer C Xu, O Nikolova, RS Basom, RM Mitchell, R Shaw, RD Moser, H Park, ... Clinical Cancer Research 24 (12), 2828-2843, 2018 | 27 | 2018 |
Disrupting the MYC-TFEB circuit impairs amino acid homeostasis and provokes metabolic anergy MR Fernandez, FX Schaub, C Yang, W Li, S Yun, SK Schaub, FC Dorsey, ... Cancer research 82 (7), 1234-1250, 2022 | 10 | 2022 |
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function AE Berglund, KEN Scott, W Li, C Yang, MR Fernandez, FX Schaub, ... Oncotarget 7 (50), 83462, 2016 | 10 | 2016 |
Tipping the MYC–MIZ 1 balance: targeting the HUWE 1 ubiquitin ligase selectively blocks MYC‐activated genes FX Schaub, JL Cleveland EMBO Molecular Medicine 6 (12), 1509-1511, 2014 | 9 | 2014 |
personalized medicine: a CLIA-certified high-throughput drug screening platform for ovarian cancer HA Swan, R Rosati, C Bridgwater, MJ Churchill, RM Watt, RC Shaw, ... Cancer Research 78 (13_Supplement), 1619-1619, 2018 | 5 | 2018 |
Predictive value of a CLIA-approved organoid based drug sensitivity test. A Margossian, A Richardson, M Churchill, F Schaub, R Rosati, ... Journal of Clinical Oncology 38 (15_suppl), 3630-3630, 2020 | 3 | 2020 |
Transition to homozygosity does not appear to provide a clonal advantage to hematopoietic progenitors carrying mutations in TET2 FX Schaub, T Lehmann, R Looser, H Hao-Shen, A Tichelli, RC Skoda Blood, The Journal of the American Society of Hematology 117 (6), 2075-2076, 2011 | 3 | 2011 |
Characterization of del20q in peripheral blood of MPD patients using copy number analysis and high resolution oligonucleotide CGH array F Schaub, R Tiedt, S Hermouet, F Girodon, R Kralovics, A Tichelli, ... Blood, The Journal of the American Society of Hematology 110 (11), 1530-1530, 2007 | 3 | 2007 |