Catalytic hydrotrifluoromethylation of unactivated alkenes S Mizuta, S Verhoog, KM Engle, T Khotavivattana, M O’duill, ... Journal of the American Chemical Society 135 (7), 2505-2508, 2013 | 431 | 2013 |
Outer-sphere dissociative electron transfer to organic molecules: a source of radicals or carbanions? Direct and indirect electrochemistry of perfluoroalkyl bromides and iodides CP Andrieux, L Gelis, M Medebielle, J Pinson, JM Saveant Journal of the American Chemical Society 112 (9), 3509-3520, 1990 | 214 | 1990 |
Nucleophilic perfluoroalkylation of aldehydes, ketones, imines, disulfides, and diselenides C Pooput, WR Dolbier, M Médebielle The Journal of Organic Chemistry 71 (9), 3564-3568, 2006 | 206 | 2006 |
A new and efficient method for the synthesis of trifluoromethylthio-and selenoethers C Pooput, M Medebielle, WR Dolbier Organic Letters 6 (2), 301-303, 2004 | 161 | 2004 |
Pentakis (trifluoromethyl) phenyl, a Sterically Crowded and Electron-withdrawing Group: Synthesis and Acidity of Pentakis (trifluoromethyl) benzene,-toluene,-phenol, and-aniline A Kütt, V Movchun, T Rodima, T Dansauer, EB Rusanov, I Leito, ... The Journal of organic chemistry 73 (7), 2607-2620, 2008 | 149 | 2008 |
Trifluoromethylation of allylsilanes under photoredox catalysis S Mizuta, KM Engle, S Verhoog, O Galicia-López, M O’Duill, M Médebielle, ... Organic letters 15 (6), 1250-1253, 2013 | 145 | 2013 |
Tetrakis(dimethylamino)ethylene as a Useful Reductant of Some Bromodifluoromethyl Heterocycles. Application to the Synthesis of New gem-Difluorinated … C Burkholder, WR Dolbier, M Médebielle The Journal of Organic Chemistry 63 (16), 5385-5394, 1998 | 144 | 1998 |
Organophotoredox hydrodefluorination of trifluoromethylarenes with translational applicability to drug discovery JBI Sap, NJW Straathof, T Knauber, CF Meyer, M Médebielle, L Buglioni, ... Journal of the American Chemical Society 142 (20), 9181-9187, 2020 | 129 | 2020 |
Nucleophilic trifluoromethylation using trifluoromethyl iodide. A new and simple alternative for the trifluoromethylation of aldehydes and ketones S Aït-Mohand, N Takechi, M Médebielle, WR Dolbier Organic Letters 3 (26), 4271-4273, 2001 | 107 | 2001 |
Difluoromethylbenzoxazole pyrimidine thioether derivatives: a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors J Boyer, E Arnoult, M Médebielle, J Guillemont, J Unge, D Jochmans Journal of medicinal chemistry 54 (23), 7974-7985, 2011 | 105 | 2011 |
An efficient preparation of new sulfonyl fluorides and lithium sulfonates F Toulgoat, BR Langlois, M Médebielle, JY Sanchez The Journal of organic chemistry 72 (24), 9046-9052, 2007 | 96 | 2007 |
“Thermal” SRN1 Reactions: How Do They Work? Novel Evidence that the Driving Force Controls the Transition between Stepwise and Concerted Mechanisms in … C Costentin, P Hapiot, M Médebielle, JM Savéant Journal of the American Chemical Society 121 (18), 4451-4460, 1999 | 83 | 1999 |
Visible‐Light‐Mediated Metal‐Free Synthesis of Trifluoromethylselenolated Arenes C Ghiazza, V Debrauwer, C Monnereau, L Khrouz, M Médebielle, ... Angewandte Chemie International Edition 57 (36), 11781-11785, 2018 | 79 | 2018 |
Tetrakis (dimethylamino) ethylene (TDAE) mediated addition of difluoromethyl anions to heteroaryl thiocyanates. A new simple access to heteroaryl–SCF2R derivatives T Billard, BR Langlois, M Médebielle Tetrahedron Letters 42 (20), 3463-3465, 2001 | 79 | 2001 |
The syntheses of nonnucleoside, HIV-1 reverse transcriptase inhibitors containing a CF2 group: The SRN1 reactions of 2-(bromodifluoromethyl) benzoxazole with the anions derived … CR Burkholder, WR Dolbier Jr, M Médebielle Journal of Fluorine Chemistry 102 (1-2), 369-376, 2000 | 79 | 2000 |
Nucleophilic trifluoromethylation of acyl chlorides using the trifluoromethyl iodide/TDAE reagent N Takechi, S Aı̈t-Mohand, M Médebielle, WR Dolbier Jr Tetrahedron letters 43 (24), 4317-4319, 2002 | 77 | 2002 |
Original reaction of p-nitrobenzyl chloride with aldehydes using tetrakis (dimethylamino) ethylene (TDAE) G Giuglio-Tonolo, T Terme, M Médebielle, P Vanelle Tetrahedron letters 44 (34), 6433-6435, 2003 | 76 | 2003 |
Incorporation of a 3-(2, 2, 2-trifluoroethyl)-γ-hydroxy-γ-lactam motif in the side chain of 4-aminoquinolines. Syntheses and antimalarial activities D Cornut, H Lemoine, O Kanishchev, E Okada, F Albrieux, AH Beavogui, ... Journal of medicinal chemistry 56 (1), 73-83, 2013 | 72 | 2013 |
Synthesis and reactivity of halogeno-difluoromethyl aromatics and heterocycles: Application to the synthesis of gem-difluorinated bioactive compounds CR Burkholder, WR Dolbier Jr, M Médebielle Journal of Fluorine Chemistry 109 (1), 39-48, 2001 | 71 | 2001 |
Trifluoromethylation reactions with potassium trifluoromethanesulfinate under electrochemical oxidation JB Tommasino, A Brondex, M Médebielle, M Thomalla, BR Langlois, ... Synlett 2002 (10), 1697-1699, 2002 | 69 | 2002 |