Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ... Nature cell biology 16 (12), 1180-1191, 2014 | 2923 | 2014 |
Interleukin-6 signaling drives fibrosis in unresolved inflammation CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ... Immunity 40 (1), 40-50, 2014 | 386 | 2014 |
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells GW Jones, RM McLoughlin, VJ Hammond, CR Parker, JD Williams, ... The journal of immunology 184 (4), 2130-2139, 2010 | 238 | 2010 |
Esterified eicosanoids: generation, characterization and function VJ Hammond, VB O'Donnell Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (10), 2403-2412, 2012 | 120 | 2012 |
Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease S Uderhardt, JA Ackermann, T Fillep, VJ Hammond, J Willeit, P Santer, ... Journal of Experimental Medicine 214 (7), 2121-2138, 2017 | 108 | 2017 |
Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection SR Clark, CJ Guy, MJ Scurr, PR Taylor, AP Kift-Morgan, VJ Hammond, ... Blood, The Journal of the American Society of Hematology 117 (6), 2033-2043, 2011 | 104 | 2011 |
Alveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challenge SA Mathie, KL Dixon, SA Walker, V Tyrrell, M Mondhe, VB O'Donnell, ... Allergy 70 (1), 80-89, 2015 | 103 | 2015 |
Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation SR Clark, CP Thomas, VJ Hammond, M Aldrovandi, GW Wilkinson, ... Proceedings of the National Academy of Sciences 110 (15), 5875-5880, 2013 | 99 | 2013 |
Quantitative assays for esterified oxylipins generated by immune cells AH Morgan, VJ Hammond, L Morgan, CP Thomas, KA Tallman, ... Nature protocols 5 (12), 1919-1931, 2010 | 69 | 2010 |
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ VJ Hammond, AH Morgan, S Lauder, CP Thomas, S Brown, BA Freeman, ... Journal of Biological Chemistry 287 (50), 41651-41666, 2012 | 67 | 2012 |
Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation [S] M Aldrovandi, VJ Hammond, H Podmore, M Hornshaw, SR Clark, ... Journal of lipid research 54 (11), 3085-3097, 2013 | 61 | 2013 |
Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells S Crittenden, M Goepp, J Pollock, CT Robb, DJ Smyth, Y Zhou, ... Science advances 7 (7), eabd7954, 2021 | 59 | 2021 |
Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway N Ipseiz, RJ Pickering, M Rosas, VJ Tyrrell, LC Davies, SJ Orr, ... The EMBO journal 39 (14), e103454, 2020 | 58 | 2020 |
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis SN Lauder, K Allen-Redpath, DA Slatter, M Aldrovandi, A O’Connor, ... Science signaling 10 (507), eaan2787, 2017 | 52 | 2017 |
Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies DA Slatter, CL Percy, K Allen-Redpath, JM Gajsiewicz, NJ Brooks, ... JCI insight 3 (6), 2019 | 51 | 2019 |
Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis H Gallagher, JO Williams, N Ferekidis, A Ismail, YH Chan, DR Michael, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (9 …, 2019 | 49 | 2019 |
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation M Misheva, K Kotzamanis, LC Davies, VJ Tyrrell, PRS Rodrigues, ... Nature communications 13 (1), 139, 2022 | 48 | 2022 |
Preferential generation of 15-HETE-PE induced by IL-13 regulates goblet cell differentiation in human airway epithelial cells J Zhao, Y Minami, E Etling, JM Coleman, SN Lauder, V Tyrrell, ... American journal of respiratory cell and molecular biology 57 (6), 692-701, 2017 | 45 | 2017 |
The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses Z Saud, VJ Tyrrell, A Zaragkoulias, MB Protty, E Statkute, A Rubina, ... Journal of Lipid Research 63 (6), 2022 | 44 | 2022 |
A novel role for 12/15-lipoxygenase in regulating autophagy AH Morgan, VJ Hammond, M Sakoh-Nakatogawa, Y Ohsumi, CP Thomas, ... Redox biology 4, 40-47, 2015 | 44 | 2015 |