CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc− and thereby promotes tumor growth T Ishimoto, O Nagano, T Yae, M Tamada, T Motohara, H Oshima, ... Cancer cell 19 (3), 387-400, 2011 | 1205 | 2011 |
Clinical impact of serum exosomal microRNA‐21 as a clinical biomarker in human esophageal squamous cell carcinoma Y Tanaka, H Kamohara, K Kinoshita, J Kurashige, T Ishimoto, M Iwatsuki, ... Cancer 119 (6), 1159-1167, 2013 | 508 | 2013 |
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell T Yae, K Tsuchihashi, T Ishimoto, T Motohara, M Yoshikawa, GJ Yoshida, ... Nature communications 3 (1), 883, 2012 | 386 | 2012 |
Human microbiome Fusobacterium nucleatum in esophageal cancer tissue is associated with prognosis K Yamamura, Y Baba, S Nakagawa, K Mima, K Miyake, K Nakamura, ... Clinical Cancer Research 22 (22), 5574-5581, 2016 | 378 | 2016 |
Prognostic nutritional index, tumor-infiltrating lymphocytes, and prognosis in patients with esophageal cancer K Okadome, Y Baba, T Yagi, Y Kiyozumi, T Ishimoto, M Iwatsuki, ... Annals of Surgery 271 (4), 693-700, 2020 | 292 | 2020 |
Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment L Bu, H Baba, N Yoshida, K Miyake, T Yasuda, T Uchihara, P Tan, ... Oncogene 38 (25), 4887-4901, 2019 | 266 | 2019 |
Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells M Tamada, O Nagano, S Tateyama, M Ohmura, T Yae, T Ishimoto, ... Cancer research 72 (6), 1438-1448, 2012 | 258 | 2012 |
CD44s Regulates the TGF-β–mediated mesenchymal phenotype and is associated with poor prognosis in patients with hepatocellular carcinoma K Mima, H Okabe, T Ishimoto, H Hayashi, S Nakagawa, H Kuroki, ... Cancer research 72 (13), 3414-3423, 2012 | 241 | 2012 |
Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer V Kumar, K Ramnarayanan, R Sundar, N Padmanabhan, S Srivastava, ... Cancer discovery 12 (3), 670-691, 2022 | 234 | 2022 |
Activation of transforming growth factor beta 1 signaling in gastric cancer-associated fibroblasts increases their motility, via expression of rhomboid 5 homolog 2, and ability … T Ishimoto, K Miyake, T Nandi, M Yashiro, N Onishi, KK Huang, SJ Lin, ... Gastroenterology 153 (1), 191-204. e16, 2017 | 205 | 2017 |
xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma M Yoshikawa, K Tsuchihashi, T Ishimoto, T Yae, T Motohara, E Sugihara, ... Cancer research 73 (6), 1855-1866, 2013 | 196 | 2013 |
CXCL12/CXCR4 activation by cancer‐associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer D Izumi, T Ishimoto, K Miyake, H Sugihara, K Eto, H Sawayama, T Yasuda, ... International journal of cancer 138 (5), 1207-1219, 2016 | 185 | 2016 |
The gut microbiota in inflammatory bowel disease P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang, Y Liu Frontiers in cellular and infection microbiology 12, 733992, 2022 | 183 | 2022 |
Tumor Necrosis Factor-α Regulates Transforming Growth Factor-β-dependent Epithelial-Mesenchymal Transition by Promoting Hyaluronan-CD44-Moesin Interaction 2 E Takahashi, O Nagano, T Ishimoto, T Yae, Y Suzuki, T Shinoda, ... Journal of Biological Chemistry 285 (6), 4060-4073, 2010 | 183 | 2010 |
Tumor immune microenvironment and immune checkpoint inhibitors in esophageal squamous cell carcinoma Y Baba, D Nomoto, K Okadome, T Ishimoto, M Iwatsuki, Y Miyamoto, ... Cancer science 111 (9), 3132-3141, 2020 | 181 | 2020 |
CD44+ slow‐cycling tumor cell expansion is triggered by cooperative actions of Wnt and prostaglandin E2 in gastric tumorigenesis T Ishimoto, H Oshima, M Oshima, K Kai, R Torii, T Masuko, H Baba, ... Cancer science 101 (3), 673-678, 2010 | 173 | 2010 |
PD-L1 expression, tumor-infiltrating lymphocytes, and clinical outcome in patients with surgically resected esophageal cancer T Yagi, Y Baba, T Ishimoto, M Iwatsuki, Y Miyamoto, N Yoshida, ... Annals of surgery 269 (3), 471-478, 2019 | 171 | 2019 |
Prognostic nutritional index predicts outcomes of gastrectomy in the elderly M Watanabe, M Iwatsuki, S Iwagami, T Ishimoto, Y Baba, H Baba World journal of surgery 36, 1632-1639, 2012 | 162 | 2012 |
An imbalance in TAZ and YAP expression in hepatocellular carcinoma confers cancer stem cell–like behaviors contributing to disease progression H Hayashi, T Higashi, N Yokoyama, T Kaida, K Sakamoto, Y Fukushima, ... Cancer research 75 (22), 4985-4997, 2015 | 150 | 2015 |
Preoperative nutritional assessment by controlling nutritional status (CONUT) is useful to estimate postoperative morbidity after esophagectomy for esophageal cancer N Yoshida, Y Baba, H Shigaki, K Harada, M Iwatsuki, J Kurashige, ... World journal of surgery 40, 1910-1917, 2016 | 149 | 2016 |