| Control of peripheral nerve myelination by the β-secretase BACE1 M Willem, AN Garratt, B Novak, M Citron, S Kaufmann, A Rittger, ... Science 314 (5799), 664-666, 2006 | 919 | 2006 |
| TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ... Science translational medicine 6 (243), 243ra86-243ra86, 2014 | 761 | 2014 |
| A γ‐secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish A Geling, H Steiner, M Willem, L Bally‐Cuif, C Haass EMBO reports, 2002 | 630 | 2002 |
| Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis A Flügel, T Berkowicz, T Ritter, M Labeur, DE Jenne, Z Li, JW Ellwart, ... Immunity 14 (5), 547-560, 2001 | 577 | 2001 |
| The β-secretase BACE1 in Alzheimer’s disease H Hampel, R Vassar, B De Strooper, J Hardy, M Willem, N Singh, J Zhou, ... Biological psychiatry 89 (8), 745-756, 2021 | 488 | 2021 |
| Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE S Parhizkar, T Arzberger, M Brendel, G Kleinberger, M Deussing, C Focke, ... Nature neuroscience 22 (2), 191-204, 2019 | 456 | 2019 |
| η-Secretase processing of APP inhibits neuronal activity in the hippocampus M Willem, S Tahirovic, MA Busche, SV Ovsepian, M Chafai, S Kootar, ... Nature 526 (7573), 443-447, 2015 | 444 | 2015 |
| Phosphorylation regulates intracellular trafficking of β-secretase J Walter, R Fluhrer, B Hartung, M Willem, C Kaether, A Capell, S Lammich, ... Journal of Biological Chemistry 276 (18), 14634-14641, 2001 | 380 | 2001 |
| Maturation and pro-peptide cleavage of β-secretase A Capell, H Steiner, M Willem, H Kaiser, C Meyer, J Walter, S Lammich, ... Journal of Biological Chemistry 275 (40), 30849-30854, 2000 | 370 | 2000 |
| Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons PH Kuhn, K Koroniak, S Hogl, A Colombo, U Zeitschel, M Willem, ... The EMBO journal 31 (14), 3157-3168, 2012 | 361 | 2012 |
| Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation K Leuner, T Schütt, C Kurz, SH Eckert, C Schiller, A Occhipinti, S Mai, ... Antioxidants & redox signaling 16 (12), 1421-1433, 2012 | 352 | 2012 |
| A critical function of the pial basement membrane in cortical histogenesis W Halfter, S Dong, YP Yip, M Willem, U Mayer Journal of Neuroscience 22 (14), 6029-6040, 2002 | 325 | 2002 |
| Insulin-degrading enzyme rapidly removes the β-amyloid precursor protein intracellular domain (AICD) D Edbauer, M Willem, S Lammich, H Steiner, C Haass Journal of Biological Chemistry 277 (16), 13389-13393, 2002 | 294 | 2002 |
| Specific ablation of the nidogen-binding site in the laminin γ1 chain interferes with kidney and lung development M Willem, N Miosge, W Halfter, N Smyth, I Jannetti, E Burghart, R Timpl, ... Oxford University Press for The Company of Biologists Limited 129 (11), 2711 …, 2002 | 229 | 2002 |
| Impaired axonal regeneration in α7 integrin-deficient mice A Werner, M Willem, LL Jones, GW Kreutzberg, U Mayer, G Raivich Journal of Neuroscience 20 (5), 1822-1830, 2000 | 201 | 2000 |
| Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface C Kaether, S Schmitt, M Willem, C Haass Traffic 7 (4), 408-415, 2006 | 198 | 2006 |
| Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region K Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ... EMBO molecular medicine 12 (4), e11227, 2020 | 193 | 2020 |
| Gene transfer into CD4+ T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses A Flügel, M Willem, T Berkowicz, H Wekerle Nature Medicine 5 (7), 843-847, 1999 | 189 | 1999 |
| Young microglia restore amyloid plaque clearance of aged microglia A Daria, A Colombo, G Llovera, H Hampel, M Willem, A Liesz, C Haass, ... The EMBO journal 36 (5), 583-603, 2017 | 170 | 2017 |
| Bace1 and Neuregulin‐1 cooperate to control formation and maintenance of muscle spindles C Cheret, M Willem, FR Fricker, H Wende, A Wulf‐Goldenberg, ... The EMBO journal 32 (14), 2015-2028, 2013 | 163 | 2013 |
