Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors JI Herschkowitz, K Simin, VJ Weigman, I Mikaelian, J Usary, Z Hu, ... Genome biology 8, 1-17, 2007 | 1689 | 2007 |
Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGFβ receptor family A Letsou, K Arora, JL Wrana, K Simin, V Twombly, J Jamal, ... Cell 80 (6), 899-908, 1995 | 359 | 1995 |
Aldehyde dehydrogenase is regulated by β-catenin/TCF and promotes radioresistance in prostate cancer progenitor cells M Cojoc, C Peitzsch, I Kurth, F Trautmann, LA Kunz-Schughart, ... Cancer research 75 (7), 1482-1494, 2015 | 263 | 2015 |
GLI1 regulates a novel neuropilin‐2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation HL Goel, B Pursell, C Chang, LM Shaw, J Mao, K Simin, P Kumar, ... EMBO molecular medicine 5 (4), 488-508, 2013 | 195 | 2013 |
Analysis of integrin β4 expression in human breast cancer: association with basal-like tumors and prognostic significance S Lu, K Simin, A Khan, AM Mercurio Clinical cancer research 14 (4), 1050-1058, 2008 | 156 | 2008 |
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis M Rajurkar, WE De Jesus-Monge, DR Driscoll, VA Appleman, H Huang, ... Proceedings of the National Academy of Sciences 109 (17), E1038-E1047, 2012 | 148 | 2012 |
A functional Notch–survivin gene signature in basal breast cancer CW Lee, K Simin, Q Liu, J Plescia, M Guha, A Khan, CC Hsieh, DC Altieri Breast Cancer Research 10, 1-12, 2008 | 146 | 2008 |
Selenium detoxification is required for cancer-cell survival AE Carlisle, N Lee, AN Matthew-Onabanjo, ME Spears, SJ Park, ... Nature metabolism 2 (7), 603-611, 2020 | 120 | 2020 |
mnd2: a new mouse model of inherited motor neuron disease JM Jones, RL Albin, EL Feldman, K Simin, TG Schuster, WA Dunnick, ... Genomics 16 (3), 669-677, 1993 | 90 | 1993 |
pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia K Simin, H Wu, L Lu, D Pinkel, D Albertson, RD Cardiff, TV Dyke PLoS biology 2 (2), e22, 2004 | 87 | 2004 |
Genetic analysis of punt, a type II Dpp receptor that functions throughout the Drosophila melanogaster life cycle K Simin, EA Bates, MA Horner, A Letsou Genetics 148 (2), 801-813, 1998 | 55 | 1998 |
The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand IP Ivanov, K Simin, A Letsou, JF Atkins, RF Gesteland Molecular and cellular biology, 1998 | 43 | 1998 |
Cooperativity of Rb, Brca1, and p53 in Malignant Breast Cancer Evolution P Kumar, M Mukherjee, JPS Johnson, M Patel, B Huey, DG Albertson, ... PLoS genetics 8 (11), e1003027, 2012 | 41 | 2012 |
Insertional mutation of the hairless locus on mouse chromosome 14 JM Jones, JT Elder, K Simin, SA Keller, MH Meisler Mammalian Genome 4, 639-643, 1993 | 37 | 1993 |
The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner DW Serber, A Rogala, M Makarem, GB Rosson, K Simin, V Godfrey, ... PloS one 7 (2), e31346, 2012 | 36 | 2012 |
The Dkk3 gene encodes a vital intracellular regulator of cell proliferation JL Leonard, DM Leonard, SA Wolfe, J Liu, J Rivera, M Yang, RT Leonard, ... PLoS One 12 (7), e0181724, 2017 | 31 | 2017 |
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance L Chibaya, KC Murphy, KD DeMarco, S Gopalan, H Liu, CN Parikh, ... Nature cancer 4 (6), 872-892, 2023 | 27 | 2023 |
Gene expression signature of atypical breast hyperplasia and regulation by SFRP1 KJ Gregory, AL Roberts, EM Conlon, JA Mayfield, MJ Hagen, GM Crisi, ... Breast Cancer Research 21, 1-18, 2019 | 26 | 2019 |
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system NC D’Amato, JH Ostrander, ML Bowie, C Sistrunk, A Borowsky, ... Public Library of Science 7 (9), e45684, 2012 | 26 | 2012 |
scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila A Scuderi, K Simin, SG Kazuko, JE Metherall, A Letsou Developmental biology 291 (1), 110-122, 2006 | 26 | 2006 |