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Karl Simin, PhD
Karl Simin, PhD
Associate Professor of Molecular, Cell and Cancer Biology, UMass Medical School
在 umassmed.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
JI Herschkowitz, K Simin, VJ Weigman, I Mikaelian, J Usary, Z Hu, ...
Genome biology 8, 1-17, 2007
16892007
Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGFβ receptor family
A Letsou, K Arora, JL Wrana, K Simin, V Twombly, J Jamal, ...
Cell 80 (6), 899-908, 1995
3591995
Aldehyde dehydrogenase is regulated by β-catenin/TCF and promotes radioresistance in prostate cancer progenitor cells
M Cojoc, C Peitzsch, I Kurth, F Trautmann, LA Kunz-Schughart, ...
Cancer research 75 (7), 1482-1494, 2015
2632015
GLI1 regulates a novel neuropilin‐2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
HL Goel, B Pursell, C Chang, LM Shaw, J Mao, K Simin, P Kumar, ...
EMBO molecular medicine 5 (4), 488-508, 2013
1952013
Analysis of integrin β4 expression in human breast cancer: association with basal-like tumors and prognostic significance
S Lu, K Simin, A Khan, AM Mercurio
Clinical cancer research 14 (4), 1050-1058, 2008
1562008
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
M Rajurkar, WE De Jesus-Monge, DR Driscoll, VA Appleman, H Huang, ...
Proceedings of the National Academy of Sciences 109 (17), E1038-E1047, 2012
1482012
A functional Notchsurvivin gene signature in basal breast cancer
CW Lee, K Simin, Q Liu, J Plescia, M Guha, A Khan, CC Hsieh, DC Altieri
Breast Cancer Research 10, 1-12, 2008
1462008
Selenium detoxification is required for cancer-cell survival
AE Carlisle, N Lee, AN Matthew-Onabanjo, ME Spears, SJ Park, ...
Nature metabolism 2 (7), 603-611, 2020
1202020
mnd2: a new mouse model of inherited motor neuron disease
JM Jones, RL Albin, EL Feldman, K Simin, TG Schuster, WA Dunnick, ...
Genomics 16 (3), 669-677, 1993
901993
pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia
K Simin, H Wu, L Lu, D Pinkel, D Albertson, RD Cardiff, TV Dyke
PLoS biology 2 (2), e22, 2004
872004
Genetic analysis of punt, a type II Dpp receptor that functions throughout the Drosophila melanogaster life cycle
K Simin, EA Bates, MA Horner, A Letsou
Genetics 148 (2), 801-813, 1998
551998
The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand
IP Ivanov, K Simin, A Letsou, JF Atkins, RF Gesteland
Molecular and cellular biology, 1998
431998
Cooperativity of Rb, Brca1, and p53 in Malignant Breast Cancer Evolution
P Kumar, M Mukherjee, JPS Johnson, M Patel, B Huey, DG Albertson, ...
PLoS genetics 8 (11), e1003027, 2012
412012
Insertional mutation of the hairless locus on mouse chromosome 14
JM Jones, JT Elder, K Simin, SA Keller, MH Meisler
Mammalian Genome 4, 639-643, 1993
371993
The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner
DW Serber, A Rogala, M Makarem, GB Rosson, K Simin, V Godfrey, ...
PloS one 7 (2), e31346, 2012
362012
The Dkk3 gene encodes a vital intracellular regulator of cell proliferation
JL Leonard, DM Leonard, SA Wolfe, J Liu, J Rivera, M Yang, RT Leonard, ...
PLoS One 12 (7), e0181724, 2017
312017
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance
L Chibaya, KC Murphy, KD DeMarco, S Gopalan, H Liu, CN Parikh, ...
Nature cancer 4 (6), 872-892, 2023
272023
Gene expression signature of atypical breast hyperplasia and regulation by SFRP1
KJ Gregory, AL Roberts, EM Conlon, JA Mayfield, MJ Hagen, GM Crisi, ...
Breast Cancer Research 21, 1-18, 2019
262019
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system
NC D’Amato, JH Ostrander, ML Bowie, C Sistrunk, A Borowsky, ...
Public Library of Science 7 (9), e45684, 2012
262012
scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila
A Scuderi, K Simin, SG Kazuko, JE Metherall, A Letsou
Developmental biology 291 (1), 110-122, 2006
262006
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