Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways P Jie, Z Hong, Y Tian, Y Li, L Lin, L Zhou, Y Du, L Chen Cell Death & Disease 6 (6), e1775-e1775, 2015 | 114 | 2015 |
Hypothalamic-pituitary-adrenal axis hyperactivity accounts for anxiety-and depression-like behaviors in rats perinatally exposed to bisphenol A F Chen, L Zhou, Y Bai, R Zhou, L Chen Journal of biomedical research 29 (3), 250, 2015 | 95 | 2015 |
Sex differences in the adult HPA axis and affective behaviors are altered by perinatal exposure to a low dose of bisphenol A F Chen, L Zhou, Y Bai, R Zhou, L Chen Brain research 1571, 12-24, 2014 | 86 | 2014 |
Activation of transient receptor potential vanilloid 4 is involved in neuronal injury in middle cerebral artery occlusion in mice P Jie, Z Lu, Z Hong, L Li, L Zhou, Y Li, R Zhou, Y Zhou, Y Du, L Chen, ... Molecular neurobiology 53, 8-17, 2016 | 81 | 2016 |
Activation of transient receptor potential vanilloid 4 increases NMDA-activated current in hippocampal pyramidal neurons L Li, W Qu, L Zhou, Z Lu, P Jie, L Chen, L Chen Frontiers in cellular neuroscience 7, 17, 2013 | 74 | 2013 |
Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of … C Wang, T Chen, G Li, L Zhou, S Sha, L Chen Neuropharmacology 97, 122-132, 2015 | 69 | 2015 |
Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons J Hong, S Sha, L Zhou, C Wang, J Yin, L Chen Cell death & disease 6 (7), e1832-e1832, 2015 | 57 | 2015 |
Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice P Jie, Y Tian, Z Hong, L Li, L Zhou, L Chen, L Chen Frontiers in Cellular Neuroscience 9, 141, 2015 | 54 | 2015 |
Lack of seipin in neurons results in anxiety-and depression-like behaviors via down regulation of PPARγ L Zhou, J Yin, C Wang, J Liao, G Liu, L Chen Human Molecular Genetics 23 (15), 4094-4102, 2014 | 54 | 2014 |
Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: A potential role for metabotropic … R Zhou, F Chen, X Feng, L Zhou, Y Li, L Chen Journal of psychiatric research 64, 121-129, 2015 | 49 | 2015 |
Activation of PPARγ ameliorates spatial cognitive deficits through restoring expression of AMPA receptors in seipin knock-out mice L Zhou, T Chen, G Li, C Wu, C Wang, L Li, S Sha, L Chen, G Liu, L Chen Journal of Neuroscience 36 (4), 1242-1253, 2016 | 41 | 2016 |
Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice L Zhou, J Flores, A Noël, O Beauchet, PJ Sjöström, AC LeBlanc Acta neuropathologica communications 7, 1-18, 2019 | 31 | 2019 |
Transient receptor potential vanilloid 4 mediates hypotonicity‐induced enhancement of synaptic transmission in hippocampal slices L Li, J Yin, PH Jie, ZH Lu, LB Zhou, L Chen, L Chen CNS neuroscience & therapeutics 19 (11), 854-862, 2013 | 25 | 2013 |
Simvastatin enhances spatial memory and long-term potentiation in hippocampal CA1 via upregulation of α7 nicotinic acetylcholine receptor T Chen, C Wang, S Sha, L Zhou, L Chen, L Chen Molecular neurobiology 53, 4060-4072, 2016 | 24 | 2016 |
Deficits in cognitive function and hippocampal plasticity in GM2/GD2 synthase knockout mice S Sha, L Zhou, J Yin, K Takamiya, K Furukawa, K Furukawa, M Sokabe, ... Hippocampus 24 (4), 369-382, 2014 | 24 | 2014 |
Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ G Li, L Zhou, Y Zhu, C Wang, S Sha, X Xian, Y Ji, G Liu, L Chen Disease Models & Mechanisms 8 (12), 1615-1624, 2015 | 21 | 2015 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca2+ influx of NMDA receptors L Li, R Yang, K Sun, Y Bai, Z Zhang, L Zhou, Z Qi, J Qi, L Chen International Journal of Neuropsychopharmacology 15 (4), 497-507, 2012 | 21 | 2012 |
Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6 A Noël, L Zhou, B Foveau, PJ Sjöström, AC LeBlanc Cell Death & Differentiation 25 (7), 1319-1335, 2018 | 15 | 2018 |
Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity A Tubeleviciute-Aydin, L Zhou, G Sharma, IV Soni, SN Savinov, JA Hardy, ... Scientific Reports 8 (1), 4428, 2018 | 12 | 2018 |
Pro-neurogenesis and anti-dementia properties of tetradecyl 2, 3-dihydroxybenzoate through TrkA receptor-mediated signalling pathways L Zhou, Z Lu, L Li, L Chen, J Qi, L Chen International Journal of Neuropsychopharmacology 17 (11), 1847-1861, 2014 | 11 | 2014 |