RNA-guided DNA insertion with CRISPR-associated transposases J Strecker, A Ladha, Z Gardner, JL Schmid-Burgk, KS Makarova, ... Science 365 (6448), 48-53, 2019 | 574 | 2019 |
Mitosis inhibits DNA double-strand break repair to guard against telomere fusions A Orthwein, A Fradet-Turcotte, SM Noordermeer, MD Canny, CM Brun, ... Science 344 (6180), 189-193, 2014 | 366 | 2014 |
Engineering of CRISPR-Cas12b for human genome editing J Strecker, S Jones, B Koopal, J Schmid-Burgk, B Zetsche, L Gao, ... Nature communications 10 (1), 212, 2019 | 345 | 2019 |
Highly parallel profiling of Cas9 variant specificity JL Schmid-Burgk, L Gao, D Li, Z Gardner, J Strecker, B Lash, F Zhang Molecular cell 78 (4), 794-800. e8, 2020 | 164 | 2020 |
High-resolution structure of Cas13b and biochemical characterization of RNA targeting and cleavage IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ... Cell reports 26 (13), 3741-3751. e5, 2019 | 106 | 2019 |
Prokaryotic innate immunity through pattern recognition of conserved viral proteins LA Gao, ME Wilkinson, J Strecker, KS Makarova, RK Macrae, EV Koonin, ... Science 377 (6607), eabm4096, 2022 | 105 | 2022 |
Dual modes of CRISPR-associated transposon homing M Saito, A Ladha, J Strecker, G Faure, E Neumann, H Altae-Tran, ... Cell 184 (9), 2441-2453. e18, 2021 | 100 | 2021 |
DNA damage signalling targets the kinetochore to promote chromatin mobility J Strecker, GD Gupta, W Zhang, M Bashkurov, MC Landry, L Pelletier, ... Nature cell biology 18 (3), 281-290, 2016 | 97 | 2016 |
Perinuclear tethers license telomeric DSBs for a broad kinesin-and NPC-dependent DNA repair process DKC Chung, JNY Chan, J Strecker, W Zhang, S Ebrahimi-Ardebili, T Lu, ... Nature communications 6 (1), 7742, 2015 | 84 | 2015 |
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair R Oshidari, J Strecker, DKC Chung, KJ Abraham, JNY Chan, CJ Damaren, ... Nature communications 9 (1), 2567, 2018 | 83 | 2018 |
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system LCK Wan, DYL Mao, D Neculai, J Strecker, D Chiovitti, I Kurinov, G Poda, ... Nucleic acids research 41 (12), 6332-6346, 2013 | 76 | 2013 |
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding KU Ludwig, RM Schmithausen, D Li, ML Jacobs, R Hollstein, ... Nature biotechnology 39 (12), 1556-1562, 2021 | 58 | 2021 |
Therapeutic potential of egg yolk antibodies for treating Clostridium difficile infection GL Mulvey, TC Dingle, L Fang, J Strecker, GD Armstrong Journal of medical microbiology 60 (8), 1181-1187, 2011 | 45 | 2011 |
RNA-activated protein cleavage with a CRISPR-associated endopeptidase J Strecker, FE Demircioglu, D Li, G Faure, ME Wilkinson, JS Gootenberg, ... Science 378 (6622), 874-881, 2022 | 41 | 2022 |
A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres J Strecker, S Stinus, MP Caballero, RK Szilard, M Chang, D Durocher Elife 6, e23783, 2017 | 30 | 2017 |
From alpha to beta: identification of amino acids required for the N‐acetyllactosamine‐specific lectin‐like activity of bundlin RM Humphries, MS Donnenberg, J Strecker, E Kitova, JS Klassen, L Cui, ... Molecular microbiology 72 (4), 859-868, 2009 | 15 | 2009 |
Lipopolysaccharide renders transgenic mice expressing human serum amyloid P component sensitive to Shiga toxin 2 TP Griener, JG Strecker, RM Humphries, GL Mulvey, C Fuentealba, ... PLoS One 6 (6), e21457, 2011 | 14 | 2011 |
Systems, methods, and compositions for targeted nucleic acid editing F Zhang, DBT Cox, J Gootenberg, OO Abudayyeh, B Zetsche, J Strecker US Patent 11,866,697, 2024 | 12 | 2024 |
Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma I Del Priore, S Ma, J Strecker, T Jacks, LM LaFave, JD Buenrostro STAR protocols 2 (2), 100583, 2021 | 11 | 2021 |
Modularity and diversity of target selectors in Tn7 transposons G Faure, M Saito, S Benler, I Peng, YI Wolf, J Strecker, H Altae-Tran, ... Molecular cell 83 (12), 2122-2136. e10, 2023 | 8 | 2023 |