Quantitative Systems Pharmacology and Physiologically‐Based Pharmacokinetic Modeling With mrgsolve: A Hands‐On Tutorial A Elmokadem, MM Riggs, KT Baron CPT: pharmacometrics & systems pharmacology, 2019 | 70 | 2019 |
Quantification of the impact of partition coefficient prediction methods on physiologically based pharmacokinetic model output using a standardized tissue composition K Utsey, MS Gastonguay, S Russell, R Freling, MM Riggs, A Elmokadem Drug Metabolism and Disposition 48 (10), 903-916, 2020 | 41* | 2020 |
Optimal drift correction for superresolution localization microscopy with Bayesian inference A Elmokadem, J Yu Biophysical journal 109 (9), 1772-1780, 2015 | 37 | 2015 |
A quantitative modeling and simulation framework to support candidate and dose selection of anti‐SARS‐CoV‐2 monoclonal antibodies to advance bamlanivimab into a first‐in‐human … E Chigutsa, E Jordie, M Riggs, A Nirula, A Elmokadem, T Knab, JY Chien Clinical Pharmacology & Therapeutics 111 (3), 595-604, 2022 | 26 | 2022 |
Brexpiprazole pharmacokinetics in CYP2D6 poor metabolizers: using physiologically based pharmacokinetic modeling to optimize time to effective concentrations A Elmokadem, CD Bruno, C Housand, EB Jordie, CR Chow, LJ Lesko, ... The Journal of Clinical Pharmacology 62 (1), 66-75, 2022 | 10 | 2022 |
Impact of obesity on brexpiprazole pharmacokinetics: proposal for improved initiation of treatment CD Bruno, A Elmokadem, C Housand, EB Jordie, CR Chow, TP Laughren, ... The Journal of Clinical Pharmacology 62 (1), 55-65, 2022 | 9 | 2022 |
Bayesian PBPK Modeling using R/Stan/Torsten and Julia/SciML/Turing. jl A Elmokadem, Y Zhang, T Knab, E Jordie, WR Gillespie CPT: Pharmacometrics & Systems Pharmacology, 2023 | 8 | 2023 |
Low‐Dose Empagliflozin as Adjunct‐to‐Insulin Therapy in Type 1 Diabetes: A Valid Modeling and Simulation Analysis to Confirm Efficacy BA Perkins, N Soleymanlou, J Rosenstock, JS Skyler, LM Laffel, ... Diabetes, Obesity and Metabolism, 2019 | 7 | 2019 |
A Model-Informed Drug Development (MIDD) approach for a low dose of empagliflozin in patients with type 1 diabetes CK Johnston, RJ Eudy-Byrne, A Elmokadem, V Nock, J Marquard, ... Pharmaceutics 13 (4), 485, 2021 | 4 | 2021 |
DEVELOPMENT OF AN OPEN-SOURCE PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO PREDICT MATERNAL-FETAL EXPOSURES OF CYP450-METABOLIZED DRUGS. M Gastonguay, S Russell, R Freling, M Riggs, K Kay, K Utsey, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 105, S56-S56, 2019 | 2 | 2019 |
Single-molecule localization microscopy as nonlinear inverse problem J Yu, A Elmokadem Proceedings of the National Academy of Sciences 116 (41), 20438-20445, 2019 | 1 | 2019 |
M-EASE-1: A Modelling and Simulation Study Conducted to Further Characterise the Efficacy of Low-dose Empagliflozin as Adjunctive to InSulin ThErapy in Type 1 Diabetes Mellitus RJ Eudy-Byrne, A Elmokadem, MM Riggs, CK Johnston, J Marquard, ... Population Approach Group in Europe (PAGE), 2019 | 1 | 2019 |
Hierarchical deep compartment modeling: A workflow to leverage machine learning and Bayesian inference for hierarchical pharmacometric modeling A Elmokadem, M Wiens, T Knab, K Utsey, SP Callisto, D Kirouac Clinical and Translational Science 17 (10), e70045, 2024 | | 2024 |
REFINED SEMI-PHYSIOLOGICAL POPULATION PHARMACOKINETIC (POPPK) MODEL FOR ORAL FIXED-DOSE COMBINATION DATA OF CEDAZURIDINE WITH DECITABINE IN MYELODYSPLASTIC SYNDROME PATIENTS. A Oganesian, E Burroughs, D Chan, M Azab, A Elmokadem CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S51-S51, 2020 | | 2020 |
1198-P: The M-EASE Studies: A Modeling and Simulation Approach to Further Characterize the Efficacy of Low-Dose Empagliflozin as Adjunctive to Insulin Therapy in Type 1 … BA Perkins, N Soleymanlou, J Rosenstock, JS Skyler, LM Laffel, ... Diabetes 68 (Supplement_1), 2019 | | 2019 |
A Physiologically-based Pharmacokinetic Model for Voriconazole to Explore Apparent Differences in Pharmacokinetics between Adults and Children A Elmokadem, MR Gastonguay, KT Baron, K Barrett, N Zane, T Yankee, ... JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S4-S4, 2018 | | 2018 |
Statistical Models for Single Molecule Localization Microscopy AS Elmokadem University of Connecticut, 2017 | | 2017 |
Super‐resolution Imaging Shows Spatial Regulation of p130Cas Phosporylation within Focal Adhesions A Elmokadem, I Moraru, J Yu The FASEB Journal 29, LB30, 2015 | | 2015 |
Symbolic PBPK-PDE Modeling Using Open-Source Julia Tools A Elmokadem, J Davis, Y Li, E Swanson, T Knab, D Kirouac | | |
How to Make a Salad? Rethinking Pharmacometric/QSP Model Composition Using Open-Source Julia Tools A Elmokadem, E Swanson, J Davis, T Knab, D Kirouac | | |