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Aleem Syed
Aleem Syed
Dana-Farber Cancer Institute/Harvard Medical School
在 dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The MRE11–RAD50–NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair
A Syed, JA Tainer
Annual Review of Biochemistry 87 (1), 263-294, 2018
4112018
BODIPY-derived photoremovable protecting groups unmasked with green light
PP Goswami, A Syed, CL Beck, TR Albright, KM Mahoney, R Unash, ...
Journal of the American Chemical Society 137 (11), 3783-3786, 2015
2872015
Family of BODIPY photocages cleaved by single photons of visible/near-infrared light
JA Peterson, C Wijesooriya, EJ Gehrmann, KM Mahoney, PP Goswami, ...
Journal of the American Chemical Society 140 (23), 7343-7346, 2018
2682018
A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors
J Zhou, C Gelot, C Pantelidou, A Li, H Yücel, RE Davis, A Färkkilä, ...
Nature Cancer 2 (6), 598-610, 2021
2622021
Raman imaging in cell membranes, lipid-rich organelles, and lipid bilayers
A Syed, EA Smith
Annual Review of Analytical Chemistry 10 (1), 271-291, 2017
462017
GRB2 enforces homology-directed repair initiation by MRE11
Z Ye, S Xu, Y Shi, A Bacolla, A Syed, D Moiani, CL Tsai, Q Shen, G Peng, ...
Science Advances 7 (32), eabe9254, 2021
312021
Targeting allostery with avatars to design inhibitors assessed by cell activity: dissecting MRE11 endo-and exonuclease activities
D Moiani, DA Ronato, CA Brosey, AS Arvai, A Syed, JY Masson, E Petricci, ...
Methods in Enzymology 601, 205-241, 2018
242018
Single particle tracking with sterol modulation reveals the cholesterol-mediated diffusion properties of integrin receptors
N Arora, A Syed, S Sander, EA Smith
Physical Biology 11 (6), 066001, 2014
142014
Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity
A Syed, F Filandr, J Patterson-Fortin, A Bacolla, R Ravindranathan, ...
Nucleic Acids Research 51 (18), 9920-9937, 2023
122023
Ligand binding affinity and changes in the lateral diffusion of receptor for advanced glycation endproducts (RAGE)
A Syed, Q Zhu, EA Smith
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (12), 3141-3149, 2016
122016
Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution
NB Chinnam, A Syed, GL Hura, M Hammel, JA Tainer, SE Tsutakawa
Methods in Enzymology 678, 351-376, 2023
92023
Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs
ML Swift, R Zhou, A Syed, LA Moreau, B Tomasik, JA Tainer, ...
Nature Structural & Molecular Biology 30 (10), 1456-1467, 2023
82023
The number of accumulated photons and the quality of stimulated emission depletion lifetime images
A Syed, MD Lesoine, U Bhattacharjee, JW Petrich, EA Smith
Photochemistry and Photobiology 90 (4), 767-772, 2014
82014
Monitoring nuclease activity by x-ray scattering interferometry using gold nanoparticle-conjugated DNA
DJ Rosenberg, A Syed, JA Tainer, GL Hura
DNA Damage Responses: Methods and Protocols, 183-205, 2022
72022
Self-immolative phthalate esters sensitive to hydrogen peroxide and light
KM Mahoney, PP Goswami, A Syed, P Kolker, B Shannan, EA Smith, ...
The Journal of Organic Chemistry 79 (23), 11740-11743, 2014
72014
Charge transport communication through DNA by protein Fe–S clusters: How far is not too far?
A Syed, JA Tainer
ACS Central Science 5 (1), 7-9, 2019
62019
Lateral diffusion and signaling of receptor for advanced glycation end-products (RAGE): a receptor involved in chronic inflammation
A Syed, Q Zhu, EA Smith
European Biophysics Journal 47, 39-48, 2018
52018
Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology
F Filandr, V Sarpe, S Raval, DA Crowder, MF Khan, P Douglas, S Coales, ...
Nature Communications 15 (1), 2200, 2024
32024
Role of insulin receptor and insulin signaling on αPS2CβPS integrins’ lateral diffusion
D Mainali, A Syed, N Arora, EA Smith
European Biophysics Journal 43, 603-611, 2014
32014
Universally Accessible Structural Data on Macromolecular Conformation, Assembly, and Dynamics by Small Angle X-Ray Scattering (SAXS) for DNA Repair DNA repair Insights
NB Chinnam, A Syed, KH Burnett, GL Hura, JA Tainer, SE Tsutakawa
DNA Damage Responses: Methods and Protocols, 43-68, 2022
22022
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