关注
Marko Novinec
Marko Novinec
Associate Professor, University of Ljubljana
在 fkkt.uni-lj.si 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cathepsin K: a unique collagenolytic cysteine peptidase
M Novinec, B Lenarčič
Biological chemistry 394 (9), 1163-1179, 2013
1442013
Papain-like peptidases: structure, function, and evolution
M Novinec, B Lenarčič
Biomolecular concepts 4 (3), 287-308, 2013
1242013
Interaction between human cathepsins K, L, and S and elastins: mechanism of elastinolysis and inhibition by macromolecular inhibitors
M Novinec, RN Grass, WJ Stark, V Turk, A Baici, B Lenarčič
Journal of Biological Chemistry 282 (11), 7893-7902, 2007
1152007
A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods
M Novinec, M Korenč, A Caflisch, R Ranganathan, B Lenarčič, A Baici
Nature communications 5 (1), 3287, 2014
1002014
Conformational flexibility and allosteric regulation of cathepsin K
M Novinec, L Kovačič, B Lenarčič, A Baici
Biochemical Journal 429 (2), 379-389, 2010
912010
Diversity and evolution of the thyroglobulin type-1 domain superfamily
M Novinec, D Kordiš, V Turk, B Lenarcic
Molecular biology and evolution 23 (4), 744-755, 2006
652006
Cysteine cathepsin activity regulation by glycosaminoglycans
M Novinec, B Lenarčič, B Turk
BioMed research international 2014 (1), 309718, 2014
622014
Orthocaspases are proteolytically active prokaryotic caspase homologues: the case of Microcystis aeruginosa
M Klemenčič, M Novinec, M Dolinar
Molecular Microbiology 98 (1), 142-150, 2015
502015
Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells
VVV Hira, U Verbovšek, B Breznik, M Srdič, M Novinec, H Kakar, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (3), 594-603, 2017
462017
Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria
A Bubik, B Sedmak, M Novinec, B Lenarčič, TT Lah
Walter de Gruyter 389 (10), 1339-1346, 2008
432008
A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli
M Novinec, M Pavšič, B Lenarčič
Protein Expression and Purification 82 (1), 1-5, 2012
322012
Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins
M Novinec, L Kovačič, N Škrlj, V Turk, B Lenarčič
Protein expression and purification 62 (1), 75-82, 2008
292008
The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties
M Klemenčič, M Novinec, S Maier, U Hartmann, B Lenarčič
PloS one 8 (2), e56839, 2013
282013
The papain-like cysteine proteinases NbCysP6 and NbCysP7 are highly processive enzymes with substrate specificities complementary to Nicotiana benthamiana cathepsin B
M Paireder, S Tholen, A Porodko, ML Biniossek, B Mayer, M Novinec, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (4), 444-452, 2017
252017
Nicotiana benthamiana cathepsin B displays distinct enzymatic features which differ from its human relative and aleurain-like protease
M Niemer, U Mehofer, M Verdianz, A Porodko, P Schähs, D Kracher, ...
Biochimie 122, 119-125, 2016
252016
Probing the activity modification space of the cysteine peptidase cathepsin K with novel allosteric modifiers
M Novinec, B Lenarčič, A Baici
PLoS One 9 (9), e106642, 2014
252014
The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity
M Paireder, U Mehofer, S Tholen, A Porodko, P Schähs, D Maresch, ...
Archives of Biochemistry and Biophysics 603, 110-117, 2016
242016
Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication
J Kladnik, A Dolinar, J Kljun, D Perea, J Grau-Expósito, M Genescà, ...
Journal of enzyme inhibition and medicinal chemistry 37 (1), 2158-2168, 2022
232022
Human cathepsin L, a papain‐like collagenase without proline specificity
M Korenč, B Lenarčič, M Novinec
The FEBS journal 282 (22), 4328-4340, 2015
232015
An allosteric site enables fine‐tuning of cathepsin K by diverse effectors
M Novinec, M Rebernik, B Lenarčič
Febs Letters 590 (24), 4507-4518, 2016
202016
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