IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a MCT Hu, DF Lee, W Xia, LS Golfman, F Ou-Yang, JY Yang, Y Zou, S Bao, ... Cell 117 (2), 225-237, 2004 | 1089 | 2004 |
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway DF Lee, HP Kuo, CT Chen, JM Hsu, CK Chou, Y Wei, HL Sun, LY Li, ... Cell 130 (3), 440-455, 2007 | 816 | 2007 |
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome X Carvajal-Vergara, A Sevilla, SL D’Souza, YS Ang, C Schaniel, DF Lee, ... Nature 465 (7299), 808-812, 2010 | 810 | 2010 |
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation JY Yang, CS Zong, W Xia, H Yamaguchi, Q Ding, X Xie, JY Lang, CC Lai, ... Nature cell biology 10 (2), 138-148, 2008 | 796 | 2008 |
Erk associates with and primes GSK-3β for its inactivation resulting in upregulation of β-catenin Q Ding, W Xia, JC Liu, JY Yang, DF Lee, J Xia, G Bartholomeusz, Y Li, ... Molecular cell 19 (2), 159-170, 2005 | 687 | 2005 |
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network YS Ang, SY Tsai, DF Lee, J Monk, J Su, K Ratnakumar, J Ding, Y Ge, ... Cell 145 (2), 183-197, 2011 | 661 | 2011 |
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma J Ling, Y Kang, R Zhao, Q Xia, DF Lee, Z Chang, J Li, B Peng, JB Fleming, ... Cancer cell 21 (1), 105-120, 2012 | 553 | 2012 |
Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization Q Ding, X He, JM Hsu, W Xia, CT Chen, LY Li, DF Lee, JC Liu, Q Zhong, ... Molecular and cellular biology 27 (11), 4006-4017, 2007 | 472 | 2007 |
KEAP1 E3 ligase-mediated downregulation of NF-κB signaling by targeting IKKβ DF Lee, HP Kuo, M Liu, CK Chou, W Xia, Y Du, J Shen, CT Chen, L Huo, ... Molecular cell 36 (1), 131-140, 2009 | 429 | 2009 |
The crosstalk of mTOR/S6K1 and Hedgehog pathways Y Wang, Q Ding, CJ Yen, W Xia, JG Izzo, JY Lang, CW Li, JL Hsu, ... Cancer cell 21 (3), 374-387, 2012 | 397 | 2012 |
Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2 SC Wang, HC Lien, W Xia, IF Chen, HW Lo, Z Wang, M Ali-Seyed, DF Lee, ... Cancer cell 6 (3), 251-261, 2004 | 366 | 2004 |
Coordination of m6A mRNA methylation and gene transcription by ZFP217 regulates pluripotency and reprogramming F Aguilo, F Zhang, A Sancho, M Fidalgo, S Di Cecilia, A Vashisht, DF Lee, ... Cell stem cell 17 (6), 689-704, 2015 | 313 | 2015 |
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells X Zhang, S Yalcin, DF Lee, TYJ Yeh, SM Lee, J Su, SK Mungamuri, ... Nature cell biology 13 (9), 1092-1099, 2011 | 300 | 2011 |
Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor DK Giri, M Ali-Seyed, LY Li, DF Lee, P Ling, G Bartholomeusz, SC Wang, ... Molecular and cellular biology 25 (24), 11005-11018, 2005 | 265 | 2005 |
Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3β activity and associates with poor prognosis in human breast cancer Q Ding, X He, W Xia, JM Hsu, CT Chen, LY Li, DF Lee, JY Yang, X Xie, ... Cancer research 67 (10), 4564-4571, 2007 | 245 | 2007 |
Modeling familial cancer with induced pluripotent stem cells DF Lee, J Su, HS Kim, B Chang, D Papatsenko, R Zhao, Y Yuan, ... Cell 161 (2), 240-254, 2015 | 220 | 2015 |
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer Q Ding, L Huo, JY Yang, W Xia, Y Wei, Y Liao, CJ Chang, Y Yang, CC Lai, ... Cancer research 68 (15), 6109-6117, 2008 | 217 | 2008 |
Phosphorylation/Cytoplasmic Localization of p21Cip1/WAF1 Is Associated with HER2/neu Overexpression and Provides a Novel Combination Predictor for Poor … W Xia, JS Chen, X Zhou, PR Sun, DF Lee, Y Liao, BP Zhou, MC Hung Clinical cancer research 10 (11), 3815-3824, 2004 | 204 | 2004 |
Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 C Li, J Ao, J Fu, DF Lee, J Xu, D Lonard, BW O'Malley Oncogene 30 (42), 4350-4364, 2011 | 192 | 2011 |
Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells SY Tsai, C Clavel, S Kim, YS Ang, L Grisanti, DF Lee, K Kelley, M Rendl Stem cells 28 (2), 221-228, 2010 | 175 | 2010 |