Modulation of pulmonary fibrosis by IL-13Rα2 RV Lumsden, JC Worrell, D Boylan, SM Walsh, J Cramton, I Counihan, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (7 …, 2015 | 43 | 2015 |
Bi-directional communication: Conversations between fibroblasts and immune cells in systemic sclerosis JC Worrell, S O'Reilly Journal of Autoimmunity 113, 102526, 2020 | 40 | 2020 |
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses RM Pinto, S Bakshi, S Lytras, MK Zakaria, S Swingler, JC Worrell, ... Nature 619 (7969), 338-347, 2023 | 36 | 2023 |
Methyl cap binding protein 2: a key epigenetic protein in systemic sclerosis J Henderson, M Brown, S Horsburgh, L Duffy, S Wilkinson, J Worrell, ... Rheumatology 58 (3), 527-535, 2019 | 30 | 2019 |
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis J Leslie, MG Macia, S Luli, JC Worrell, WJ Reilly, HL Paish, A Knox, ... Nature metabolism 2 (11), 1350-1367, 2020 | 29 | 2020 |
CXCL9 Regulates TGF-β1–Induced Epithelial to Mesenchymal Transition in Human Alveolar Epithelial Cells SL O’Beirne, SM Walsh, A Fabre, C Reviriego, JC Worrell, IP Counihan, ... The Journal of Immunology 195 (6), 2788-2796, 2015 | 29 | 2015 |
Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis SM Walsh, JC Worrell, A Fabre, B Hinz, R Kane, MP Keane American Journal of Physiology-Lung Cellular and Molecular Physiology 315 (5 …, 2018 | 28 | 2018 |
Stromal–immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult JC Worrell, MKL MacLeod Immunology 163 (3), 239-249, 2021 | 24 | 2021 |
HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression TN Cartwright, JC Worrell, L Marchetti, CM Dowling, A Knox, P Kiely, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (10 …, 2018 | 21 | 2018 |
Serum exosomes from IPF patients display a fibrotic miRNA profile that correlates to clinical measures of disease severity P Minnis, R Kane, R Anglin, S Walsh, J Worrel, F Khan, RV Lumsden, ... European Respiratory Journal 46 (suppl 59), 2015 | 14 | 2015 |
CXCR3 Requirement for the Interleukin-13–Mediated Up-Regulation of Interleukin-13Rα2 in Pulmonary Fibroblasts JC Barnes, RV Lumsden, J Worrell, IP Counihan, SL O’Beirne, ... American Journal of Respiratory Cell and Molecular Biology 53 (2), 217-225, 2015 | 11 | 2015 |
Zoonotic avian influenza viruses evade human BTN3A3 restriction RM Pinto, S Bakshi, S Lytras, MK Zakaria, S Swingler, JC Worrell, ... bioRxiv, 2022.06. 14.496196, 2022 | 8 | 2022 |
CXCR3A promotes the secretion of the antifibrotic decoy receptor sIL-13Rα2 by pulmonary fibroblasts JC Worrell, SM Walsh, A Fabre, R Kane, B Hinz, MP Keane American Journal of Physiology-Cell Physiology 319 (6), C1059-C1069, 2020 | 6 | 2020 |
cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis JC Worrell, J Leslie, GR Smith, MYW Zaki, HL Paish, A Knox, ML James, ... Rheumatology 59 (12), 3939-3951, 2020 | 6 | 2020 |
Triphasic production of IFNγ by innate and adaptive lymphocytes following influenza A virus infection GE Finney, KE Hargrave, M Pingen, T Purnell, D Todd, F MacDonald, ... Discovery Immunology 2 (1), kyad014, 2023 | 5 | 2023 |
Antigen presenting cells: Professionals, amateurs, and spectators in the'long game'of lung immunity KE Hargrave, MKL MacLeod, JC Worrell The International Journal of Biochemistry & Cell Biology 153, 106331, 2022 | 3 | 2022 |
Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells KE Hargrave, JC Worrell, C Pirillo, E Brennan, AM Garriga, JI Gray, ... Mucosal Immunology, 2024 | 1 | 2024 |
Stromal Sulfatase-2-a critical regulator of hepatocellular carcinoma growth and migration. MY Zaki, L Borthwick, S Alhasan, J Worrell, R Shukla, D Tiniakos, ... HEPATOLOGY 66, 968A-969A, 2017 | 1 | 2017 |
The myofibroblast in pulmonary fibrosis displays distinct functional characteristics, depending on its source of origin SM Walsh, DA Boylan, JC Worrell, RV Lumsden, R Kane, MP Keane European Respiratory Journal 44 (Suppl 58), 2014 | 1 | 2014 |
Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge JC Worrell, KE Hargrave, GE Finney, C Hansell, J Cole, J Singh Nijjar, ... bioRxiv, 2024.07. 20.604410, 2024 | | 2024 |