Hydrogen exchange mass spectrometry for the analysis of protein dynamics TE Wales, JR Engen Mass spectrometry reviews 25 (1), 158-170, 2006 | 996 | 2006 |
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature Methods 16 (7), 595, 2019 | 568 | 2019 |
High-speed and high-resolution UPLC separation at zero degrees Celsius TE Wales, KE Fadgen, GC Gerhardt, JR Engen Analytical chemistry 80 (17), 6815-6820, 2008 | 382 | 2008 |
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding EC Twomey, Z Ji, TE Wales, NO Bodnar, SB Ficarro, JA Marto, JR Engen, ... Science 365 (6452), eaax1033, 2019 | 272 | 2019 |
Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis DD Weis, TE Wales, JR Engen, M Hotchko, LF Ten Eyck Journal of the American Society for Mass Spectrometry 17, 1498-1509, 2006 | 253 | 2006 |
Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice R Mourtada, HD Herce, DJ Yin, JA Moroco, TE Wales, JR Engen, ... Nature biotechnology 37 (10), 1186-1197, 2019 | 226 | 2019 |
Structure and dynamic regulation of Src-family kinases JR Engen, TE Wales, JM Hochrein, MA Meyn, SB Ozkan, I Bahar, ... Cellular and Molecular Life Sciences 65 (19), 3058-3073, 2008 | 209 | 2008 |
Inhibition of pro-apoptotic BAX by a noncanonical interaction mechanism LA Barclay, TE Wales, TP Garner, F Wachter, S Lee, RM Guerra, ... Molecular cell 57 (5), 873-886, 2015 | 153 | 2015 |
Tissue-specific oncogenic activity of KRASA146T EJ Poulin, AK Bera, J Lu, YJ Lin, SD Strasser, JA Paulo, TQ Huang, ... Cancer Discovery 9 (6), 738-755, 2019 | 150 | 2019 |
Analytical Aspects of Hydrogen Exchange Mass Spectrometry JR Engen, TE Wales Annual Review of Analytical Chemistry 8 (1), 2015 | 135 | 2015 |
Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1–Npl4 NO Bodnar, KH Kim, Z Ji, TE Wales, V Svetlov, E Nudler, JR Engen, ... Nature Structural & Molecular Biology, 1, 2018 | 100 | 2018 |
Developments in Hydrogen/Deuterium Exchange Mass Spectrometry JR Engen, T Botzanowski, D Peterle, F Georgescauld, TE Wales Analytical Chemistry 93 (1), 567-582, 2020 | 80 | 2020 |
Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein M de Wispelaere, W Lian, S Potisopon, PC Li, J Jang, SB Ficarro, ... Cell Chemical Biology, 2018 | 79 | 2018 |
Considerations in the Analysis of Hydrogen Exchange Mass Spectrometry Data TE Wales, MJ Eggertson, JR Engen Mass Spectrometry Data Analysis in Proteomics, 263-288, 2013 | 78 | 2013 |
Conformational locking upon cooperative assembly of notch transcription complexes SH Choi, TE Wales, Y Nam, DJ O'Donovan, P Sliz, JR Engen, ... Structure 20 (2), 340-349, 2012 | 74 | 2012 |
Partial unfolding of diverse SH3 domains on a wide timescale TE Wales, JR Engen Journal of molecular biology 357 (5), 1592-1604, 2006 | 72 | 2006 |
Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation K Tiyanont, TE Wales, M Aste-Amezaga, JC Aster, JR Engen, ... Structure 19 (4), 546-554, 2011 | 69 | 2011 |
Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD S Escudero, E Zaganjor, S Lee, CP Mill, AM Morgan, EB Crawford, ... Molecular cell 69 (5), 729-743. e7, 2018 | 68 | 2018 |
Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase Z Ji, H Li, D Peterle, JA Paulo, SB Ficarro, TE Wales, JA Marto, SP Gygi, ... Molecular Cell 82 (3), 570-584. e8, 2022 | 60 | 2022 |
Allosteric inhibition of antiapoptotic MCL-1 S Lee, TE Wales, S Escudero, DT Cohen, J Luccarelli, CG Gallagher, ... Nature structural & molecular biology, 2016 | 60 | 2016 |