Mechanisms of aquaporin-facilitated cancer invasion and metastasis ML De Ieso, AJ Yool Frontiers in chemistry 6, 135, 2018 | 100 | 2018 |
Bumetanide derivatives AqB007 and AqB011 selectively block the aquaporin-1 ion channel conductance and slow cancer cell migration M Kourghi, JV Pei, ML De Ieso, G Flynn, AJ Yool Molecular pharmacology 89 (1), 133-140, 2016 | 70 | 2016 |
The vital role for nitric oxide in intraocular pressure homeostasis E Reina-Torres, ML De Ieso, LR Pasquale, M Madekurozwa, ... Progress in retinal and eye research 83, 100922, 2021 | 69 | 2021 |
Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant Bacopa … JV Pei, M Kourghi, ML De Ieso, EM Campbell, HS Dorward, ... Molecular pharmacology 90 (4), 496-507, 2016 | 61 | 2016 |
Effect of compound kushen injection, a natural compound mixture, and its identified chemical components on migration and invasion of colon, brain, and breast cancer cell lines S Nourmohammadi, TN Aung, J Cui, JV Pei, ML De Ieso, Y Harata-Lee, ... Frontiers in oncology 9, 314, 2019 | 54 | 2019 |
Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life M Kourghi, JV Pei, ML De Ieso, S Nourmohammadi, PH Chow, AJ Yool Clinical and Experimental Pharmacology and Physiology 45 (4), 401-409, 2018 | 46 | 2018 |
Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow O Yarishkin, TTT Phuong, JM Baumann, ML De Ieso, F Vazquez‐Chona, ... The Journal of physiology 599 (2), 571-592, 2021 | 44 | 2021 |
An accurate and cost-effective alternative method for measuring cell migration with the circular wound closure assay ML De Ieso, JV Pei Bioscience reports 38 (5), BSR20180698, 2018 | 44 | 2018 |
Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration ML De Ieso, JV Pei, S Nourmohammadi, E Smith, PH Chow, M Kourghi, ... Scientific reports 9 (1), 12635, 2019 | 40 | 2019 |
Identification of loop D domain amino acids in the human Aquaporin-1 channel involved in activation of the ionic conductance and inhibition by AqB011 M Kourghi, ML De Ieso, S Nourmohammadi, JV Pei, AJ Yool Frontiers in chemistry 6, 142, 2018 | 26 | 2018 |
Consensus recommendation for mouse models of ocular hypertension to study aqueous humor outflow and its mechanisms CM McDowell, K Kizhatil, MH Elliott, DR Overby, ... Investigative ophthalmology & visual science 63 (2), 12-12, 2022 | 24 | 2022 |
Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, G Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology 95 (5), 573-583, 2019 | 21 | 2019 |
Physiologic consequences of caveolin-1 ablation in conventional outflow endothelia ML De Ieso, JM Gurley, ME McClellan, X Gu, I Navarro, G Li, ... Investigative ophthalmology & visual science 61 (11), 32-32, 2020 | 15 | 2020 |
Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease EN Enyong, JM Gurley, ML De Ieso, WD Stamer, MH Elliott Progress in retinal and eye research 91, 101094, 2022 | 11 | 2022 |
Drug discovery and therapeutic targets for pharmacological modulators of aquaporin channels JV Pei, JL Burton, M Kourghi, ML De Ieso, AJ Yool Aquaporins in Health and Disease: New Molecular Targets For Drug Discovery …, 2016 | 11 | 2016 |
A role of Caveolae in trabecular meshwork Mechanosensing and contractile tone ML De Ieso, M Kuhn, P Bernatchez, MH Elliott, WD Stamer Frontiers in cell and developmental biology 10, 855097, 2022 | 6 | 2022 |
Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology H Li, M Kuhn, RA Kelly, A Singh, KK Palanivel, I Salama, ML De Ieso, ... American Journal of Physiology-Cell Physiology 326 (2), C513-C528, 2024 | 2 | 2024 |
Pressure clamping during ocular perfusions drives nitric oxide-mediated washout RA Kelly, FS McDonnell, ML De Ieso, DR Overby, WD Stamer Investigative Ophthalmology & Visual Science 64 (7), 36-36, 2023 | 2 | 2023 |
Lithium'Hot-spots': Real-time Analysis of non-selective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, GM Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology, 2019 | 2 | 2019 |
Aging and intraocular pressure homeostasis in mice G Li, J van Batenburg‐Sherwood, BN Safa, NS Fraticelli Guzmán, ... Aging Cell, e14160, 2024 | 1 | 2024 |