Akt signalling in health and disease I Hers, EE Vincent, JM Tavaré Cellular signalling 23 (10), 1515-1527, 2011 | 1419 | 2011 |
Itaconate links inhibition of succinate dehydrogenase with macrophage metabolic remodeling and regulation of inflammation V Lampropoulou, A Sergushichev, M Bambouskova, S Nair, EE Vincent, ... Cell metabolism 24 (1), 158-166, 2016 | 1180 | 2016 |
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo J Blagih, F Coulombe, EE Vincent, F Dupuy, G Galicia-Vázquez, ... Immunity 42 (1), 41-54, 2015 | 636 | 2015 |
PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer F Dupuy, S Tabariès, S Andrzejewski, Z Dong, J Blagih, MG Annis, ... Cell metabolism 22 (4), 577-589, 2015 | 536 | 2015 |
The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator B Faubert, EE Vincent, MC Poffenberger, RG Jones Cancer letters 356 (2), 165-170, 2015 | 377 | 2015 |
Mitochondrial phosphoenolpyruvate carboxykinase regulates metabolic adaptation and enables glucose-independent tumor growth EE Vincent, A Sergushichev, T Griss, MC Gingras, B Samborska, ... Molecular cell 60 (2), 195-207, 2015 | 272 | 2015 |
Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α B Faubert, EE Vincent, T Griss, B Samborska, S Izreig, RU Svensson, ... Proceedings of the National Academy of Sciences 111 (7), 2554-2559, 2014 | 270 | 2014 |
Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer EE Vincent, DJE Elder, EC Thomas, L Phillips, C Morgan, J Pawade, ... British journal of cancer 104 (11), 1755-1761, 2011 | 224 | 2011 |
Metformin antagonizes cancer cell proliferation by suppressing mitochondrial-dependent biosynthesis T Griss, EE Vincent, R Egnatchik, J Chen, EH Ma, B Faubert, B Viollet, ... PLoS biology 13 (12), e1002309, 2015 | 223 | 2015 |
Differential effects of AMPK agonists on cell growth and metabolism EE Vincent, PP Coelho, J Blagih, T Griss, B Viollet, RG Jones Oncogene 34 (28), 3627-3639, 2015 | 177 | 2015 |
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway M Carbonneau, L M. Gagné, ME Lalonde, MA Germain, A Motorina, ... Nature communications 7 (1), 12700, 2016 | 164 | 2016 |
Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study CJ Bull, JA Bell, N Murphy, E Sanderson, G Davey Smith, NJ Timpson, ... BMC medicine 18, 1-16, 2020 | 108 | 2020 |
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, ... Nature communications 12 (1), 1209, 2021 | 107 | 2021 |
Influence of puberty timing on adiposity and cardiometabolic traits: a Mendelian randomisation study JA Bell, D Carslake, KH Wade, RC Richmond, RJ Langdon, EE Vincent, ... PLoS medicine 15 (8), e1002641, 2018 | 98 | 2018 |
GAM: a web-service for integrated transcriptional and metabolic network analysis AA Sergushichev, AA Loboda, AK Jha, EE Vincent, EM Driggers, ... Nucleic acids research 44 (W1), W194-W200, 2016 | 95 | 2016 |
Association between genetically proxied inhibition of HMG-CoA reductase and epithelial ovarian cancer J Yarmolinsky, CJ Bull, EE Vincent, J Robinson, A Walther, GD Smith, ... Jama 323 (7), 646-655, 2020 | 92 | 2020 |
Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation N Jones, EE Vincent, JG Cronin, S Panetti, M Chambers, SR Holm, ... Nature Communications 10 (1), 2042, 2019 | 75 | 2019 |
The miR-17∼ 92 microRNA cluster is a global regulator of tumor metabolism S Izreig, B Samborska, RM Johnson, A Sergushichev, EH Ma, C Lussier, ... Cell reports 16 (7), 1915-1928, 2016 | 70 | 2016 |
Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial RA Beynon, RC Richmond, DL Santos Ferreira, AR Ness, M May, ... International journal of cancer 144 (8), 1918-1928, 2019 | 58 | 2019 |
Cholesterol auxotrophy as a targetable vulnerability in clear cell renal cell carcinoma R Riscal, CJ Bull, C Mesaros, JM Finan, M Carens, ES Ho, JP Xu, ... Cancer discovery 11 (12), 3106-3125, 2021 | 56 | 2021 |