EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ... Cancer cell 23 (5), 677-692, 2013 | 917 | 2013 |
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models E Caldas-Lopes, L Cerchietti, JH Ahn, CC Clement, AI Robles, A Rodina, ... Proceedings of the National Academy of Sciences 106 (20), 8368-8373, 2009 | 371 | 2009 |
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells JM Polo, T Dell'Oso, SM Ranuncolo, L Cerchietti, D Beck, GF Da Silva, ... Nature medicine 10 (12), 1329-1335, 2004 | 353 | 2004 |
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo LC Cerchietti, AF Ghetu, X Zhu, GF Da Silva, S Zhong, M Matthews, ... Cancer cell 17 (4), 400-411, 2010 | 347 | 2010 |
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ... Nature chemical biology 7 (11), 818-826, 2011 | 301 | 2011 |
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ... Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009 | 273 | 2009 |
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo L Fontan, C Yang, V Kabaleeswaran, L Volpon, MJ Osborne, E Beltran, ... Cancer cell 22 (6), 812-824, 2012 | 271 | 2012 |
Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer AH Navigante, LCA Cerchietti, MA Castro, MA Lutteral, ME Cabalar Journal of pain and symptom management 31 (1), 38-47, 2006 | 269 | 2006 |
The epichaperome is an integrated chaperome network that facilitates tumour survival A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ... Nature 538 (7625), 397-401, 2016 | 258 | 2016 |
Kaiso-deficient mice show resistance to intestinal cancer A Prokhortchouk, O Sansom, J Selfridge, IM Caballero, S Salozhin, ... Molecular and cellular biology 26 (1), 199-208, 2006 | 232 | 2006 |
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ... Nature 473 (7347), 384-388, 2011 | 216 | 2011 |
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma T Clozel, SN Yang, RL Elstrom, W Tam, P Martin, M Kormaksson, ... Cancer discovery 3 (9), 1002-1019, 2013 | 214 | 2013 |
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ... Nature medicine 15 (12), 1369-1376, 2009 | 206 | 2009 |
Effect of topical morphine for mucositis‐associated pain following concomitant chemoradiotherapy for head and neck carcinoma LCA Cerchietti, AH Navigante, MR Bonomi, MA Zaderajko, PR Menéndez, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2002 | 204 | 2002 |
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation HA Zahreddine, B Culjkovic-Kraljacic, S Assouline, P Gendron, ... Nature 511 (7507), 90-93, 2014 | 200 | 2014 |
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ... Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009 | 196 | 2009 |
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ... Journal of Experimental Medicine 208 (11), 2163-2174, 2011 | 193 | 2011 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 191 | 2013 |
Limits in the detection of m6A changes using MeRIP/m6A-seq ABR McIntyre, NS Gokhale, L Cerchietti, SR Jaffrey, SM Horner, ... Scientific reports 10 (1), 6590, 2020 | 176 | 2020 |
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma R Shaknovich, H Geng, NA Johnson, L Tsikitas, L Cerchietti, JM Greally, ... Blood, The Journal of the American Society of Hematology 116 (20), e81-e89, 2010 | 174 | 2010 |