A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 2572 | 2020 |
RHO–GTPases and cancer E Sahai, CJ Marshall Nature Reviews Cancer 2 (2), 133-142, 2002 | 1968 | 2002 |
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells C Gaggioli, S Hooper, C Hidalgo-Carcedo, R Grosse, JF Marshall, ... Nature cell biology 9 (12), 1392-1400, 2007 | 1756 | 2007 |
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I ML Coleman, EA Sahai, M Yeo, M Bosch, A Dewar, MF Olson Nature cell biology 3 (4), 339-345, 2001 | 1619 | 2001 |
NK cells stimulate recruitment of cDC1 into the tumor microenvironment promoting cancer immune control JP Böttcher, E Bonavita, P Chakravarty, H Blees, M Cabeza-Cabrerizo, ... Cell 172 (5), 1022-1037. e14, 2018 | 1489 | 2018 |
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis E Sahai, CJ Marshall Nature cell biology 5 (8), 711-719, 2003 | 1431 | 2003 |
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts F Calvo, N Ege, A Grande-Garcia, S Hooper, RP Jenkins, SI Chaudhry, ... Nature cell biology 15 (6), 637-646, 2013 | 1374 | 2013 |
Classifying collective cancer cell invasion P Friedl, J Locker, E Sahai, JE Segall Nature cell biology 14 (8), 777-783, 2012 | 1145 | 2012 |
Rac activation and inactivation control plasticity of tumor cell movement V Sanz-Moreno, G Gadea, J Ahn, H Paterson, P Marra, S Pinner, E Sahai, ... Cell 135 (3), 510-523, 2008 | 1115 | 2008 |
Cyclooxygenase-dependent tumor growth through evasion of immunity S Zelenay, AG Van Der Veen, JP Böttcher, KJ Snelgrove, N Rogers, ... Cell 162 (6), 1257-1270, 2015 | 1021 | 2015 |
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop S Goswami, E Sahai, JB Wyckoff, M Cammer, D Cox, FJ Pixley, ... Cancer research 65 (12), 5278-5283, 2005 | 912 | 2005 |
Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility S Giampieri, C Manning, S Hooper, L Jones, CS Hill, E Sahai Nature cell biology 11 (11), 1287-1296, 2009 | 768 | 2009 |
Illuminating the metastatic process E Sahai Nature Reviews Cancer 7 (10), 737-749, 2007 | 732 | 2007 |
Physical influences of the extracellular environment on cell migration G Charras, E Sahai Nature reviews Molecular cell biology 15 (12), 813-824, 2014 | 730 | 2014 |
A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion A Labernadie, T Kato, A Brugués, X Serra-Picamal, S Derzsi, E Arwert, ... Nature cell biology 19 (3), 224-237, 2017 | 713 | 2017 |
Mechanisms of cancer cell invasion E Sahai Current opinion in genetics & development 15 (1), 87-96, 2005 | 708 | 2005 |
The actin cytoskeleton in cancer cell motility MF Olson, E Sahai Clinical & experimental metastasis 26, 273-287, 2009 | 698 | 2009 |
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling E Hirata, MR Girotti, A Viros, S Hooper, B Spencer-Dene, M Matsuda, ... Cancer cell 27 (4), 574-588, 2015 | 601 | 2015 |
ROCK and Dia have opposing effects on adherens junctions downstream of Rho E Sahai, CJ Marshall Nature cell biology 4 (6), 408-415, 2002 | 587 | 2002 |
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors W Wang, S Goswami, K Lapidus, AL Wells, JB Wyckoff, E Sahai, ... Cancer research 64 (23), 8585-8594, 2004 | 565 | 2004 |