Identifying a high fraction of the human genome to be under selective constraint using GERP++ EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou PLoS computational biology 6 (12), e1001025, 2010 | 1851 | 2010 |
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes SB Montgomery, DL Goode, E Kvikstad, CA Albers, ZD Zhang, XJ Mu, ... Genome research 23 (5), 749-761, 2013 | 275 | 2013 |
Monogenic and polygenic determinants of sarcoma risk: an international genetic study ML Ballinger, DL Goode, I Ray-Coquard, PA James, G Mitchell, ... The Lancet Oncology 17 (9), 1261-1271, 2016 | 226 | 2016 |
Single-nucleotide evolutionary constraint scores highlight disease-causing mutations GM Cooper, DL Goode, SB Ng, A Sidow, MJ Bamshad, J Shendure, ... Nature methods 7 (4), 250-251, 2010 | 222 | 2010 |
Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors AS Trigos, RB Pearson, AT Papenfuss, DL Goode Proceedings of the National Academy of Sciences 114 (24), 6406-6411, 2017 | 195 | 2017 |
Loss of heterozygosity: what is it good for? GL Ryland, MA Doyle, D Goode, SE Boyle, DYH Choong, SM Rowley, J Li, ... BMC medical genomics 8, 1-12, 2015 | 167 | 2015 |
Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex K Belov, JE Deakin, AT Papenfuss, ML Baker, SD Melman, HV Siddle, ... PLoS biology 4 (3), e46, 2006 | 164 | 2006 |
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 152 | 2019 |
How the evolution of multicellularity set the stage for cancer AS Trigos, RB Pearson, AT Papenfuss, DL Goode British journal of cancer 118 (2), 145-152, 2018 | 135 | 2018 |
The H3K4-methyl epigenome regulates leukemia stem cell oncogenic potential SHK Wong, DL Goode, M Iwasaki, MC Wei, HP Kuo, L Zhu, ... Cancer cell 28 (2), 198-209, 2015 | 126 | 2015 |
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ... European urology 74 (5), 562-572, 2018 | 103 | 2018 |
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes DL Goode, GM Cooper, J Schmutz, M Dickson, E Gonzales, M Tsai, ... Genome research 20 (3), 301-310, 2010 | 89 | 2010 |
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 86 | 2020 |
High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort G Mitchell, ML Ballinger, S Wong, C Hewitt, P James, MA Young, ... PloS one 8 (7), e69026, 2013 | 70 | 2013 |
Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer AS Trigos, RB Pearson, AT Papenfuss, DL Goode Elife 8, e40947, 2019 | 68 | 2019 |
Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue T Kader, DL Goode, SQ Wong, J Connaughton, SM Rowley, L Devereux, ... Genome medicine 8 (1), 1-13, 2016 | 55 | 2016 |
A simple consensus approach improves somatic mutation prediction accuracy DL Goode, SM Hunter, MA Doyle, T Ma, SM Rowley, D Choong, ... Genome medicine 5 (9), 1-14, 2013 | 54 | 2013 |
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology GP Risbridger, AK Clark, LH Porter, R Toivanen, A Bakshi, NL Lister, ... Nature communications 12 (1), 5049, 2021 | 47 | 2021 |
Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs N Li, SM Rowley, ER Thompson, S McInerny, L Devereux, ... Breast Cancer Research 20, 1-11, 2018 | 34 | 2018 |
Mutations in RECQL are not associated with breast cancer risk in an Australian population N Li, SM Rowley, DL Goode, KC Amarasinghe, S McInerny, L Devereux, ... Nature genetics 50 (10), 1346-1348, 2018 | 28 | 2018 |