Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase A Kohen, R Cannio, S Bartolucci, JP Klinman, JP Klinman Nature 399 (6735), 496-499, 1999 | 666 | 1999 |
Isotope effects in chemistry and biology A Kohen, HH Limbach cRc Press, 2005 | 597 | 2005 |
Enzyme catalysis: beyond classical paradigms A Kohen, JP Klinman Accounts of Chemical Research 31 (7), 397-404, 1998 | 451 | 1998 |
Hydrogen tunneling links protein dynamics to enzyme catalysis JP Klinman, A Kohen Annual review of biochemistry 82 (1), 471-496, 2013 | 363 | 2013 |
Hydrogen tunneling in biology A Kohen, JP Klinman Chemistry & biology 6 (7), R191-R198, 1999 | 319 | 1999 |
Role of dynamics in enzyme catalysis: substantial versus semantic controversies A Kohen Accounts of chemical research 48 (2), 466-473, 2015 | 245 | 2015 |
Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis RS Sikorski, L Wang, KA Markham, PTR Rajagopalan, SJ Benkovic, ... Journal of the American Chemical Society 126 (15), 4778-4779, 2004 | 235 | 2004 |
Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase L Wang, NM Goodey, SJ Benkovic, A Kohen Proceedings of the National Academy of Sciences 103 (43), 15753-15758, 2006 | 208 | 2006 |
Convex Arrhenius plots and their interpretation DG Truhlar, A Kohen Proceedings of the National Academy of Sciences 98 (3), 848-851, 2001 | 198 | 2001 |
Arrhenius curves of hydrogen transfers: tunnel effects, isotope effects and effects of pre-equilibria HH Limbach, J Miguel Lopez, A Kohen Philosophical Transactions of the Royal Society B: Biological Sciences 361 …, 2006 | 157 | 2006 |
Effects of the donor–acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reaction V Stojković, LL Perissinotti, D Willmer, SJ Benkovic, A Kohen Journal of the American Chemical Society 134 (3), 1738-1745, 2012 | 136 | 2012 |
Effects of protein glycosylation on catalysis: changes in hydrogen tunneling and enthalpy of activation in the glucose oxidase reaction A Kohen, T Jonsson, JP Klinman Biochemistry 36 (9), 2603-2611, 1997 | 130 | 1997 |
Kinetic isotope effects as probes for hydrogen tunneling, coupled motion and dynamics contributions to enzyme catalysis A Kohen Progress in reaction kinetics and mechanism 28 (2), 119-156, 2003 | 113 | 2003 |
An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene EM Koehn, T Fleischmann, JA Conrad, BA Palfey, SA Lesley, II Mathews, ... Nature 458 (7240), 919-923, 2009 | 110 | 2009 |
Effects of a distal mutation on active site chemistry L Wang, S Tharp, T Selzer, SJ Benkovic, A Kohen Biochemistry 45 (5), 1383-1392, 2006 | 105 | 2006 |
Protein flexibility correlates with degree of hydrogen tunneling in thermophilic and mesophilic alcohol dehydrogenases A Kohen, JP Klinman Journal of the American Chemical Society 122 (43), 10738-10739, 2000 | 105 | 2000 |
Vibrationally enhanced hydrogen tunneling in the Escherichia coli thymidylate synthase catalyzed reaction N Agrawal, B Hong, C Mihai, A Kohen Biochemistry 43 (7), 1998-2006, 2004 | 104 | 2004 |
Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii Q Guo, L Gakhar, K Wickersham, K Francis, A Vardi-Kilshtain, DT Major, ... Biochemistry 55 (19), 2760-2771, 2016 | 98 | 2016 |
Line shape analysis of two-dimensional infrared spectra Q Guo, P Pagano, YL Li, A Kohen, CM Cheatum The Journal of chemical physics 142 (21), 2015 | 98 | 2015 |
Fast enzyme dynamics at the active site of formate dehydrogenase JN Bandaria, S Dutta, SE Hill, A Kohen, CM Cheatum Journal of the American Chemical society 130 (1), 22-23, 2008 | 88 | 2008 |